| Project/Area Number |
22651046
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Tokyo University of Agriculture and Technology |
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Principal Investigator |
ARAKAKI Atsushi 東京農工大学, 大学院・工学研究院, 准教授 (10367154)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,460,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,900,000 (Direct Cost: ¥1,900,000)
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| Keywords | 磁気微粒子 / 遺伝子増幅 / 誘導加熱 / 核酸回収 / 細胞破砕 |
|---|
| Research Abstract |
The aim of this research is development of a technique for gene amplification by localized heating of magnetic nanoparticles. We have applied the localized heating phenomena of magnetic nanoparticles to control the nucleicacid dissociation. In addition, the amine-modified magnetic particles have been demonstrated to inactive the microbe via the damage of the microbial membrane. Therefore, we propose to develop a nano-scale high throughput nucleic acid amplification technique further application in micro devices.
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