Self-assembly of DNA-functionalized hydrogel microstructure
| Project/Area Number |
22651049
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Microdevices/Nanodevices
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| Research Institution | The University of Tokyo |
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Principal Investigator |
ONOE Hiroaki 東京大学, 生産技術研究所, 助教 (30548681)
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| Co-Investigator(Kenkyū-buntansha) |
TAKINOUE Masahiro 東京工業大学, 大学院・総合理工学研究科, 講師 (20511249)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,440,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,400,000 (Direct Cost: ¥2,400,000)
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| Keywords | マイクロナノデバイス / Self-assembly / DNA / ハイドロゲル / ソフトマテリアル / ヤヌス粒子 / 遠心力 / ナノマシン / ゲルビーズ / 遠心器 |
|---|
| Research Abstract |
We developed a simple synthesis method of hydrogel micro-structures under ultra-high gravity created by a centrifuge. Using this method, we achieved(1) keepingthe surface of hydrogel micro-structures that can be directly modified with functional molecules,(2) creating anisotropic and multi-compartmentalized hydrogelmicro-structures by using multi-barreled capillary,(3) functionalizing the hydrogelmicro-structures by encapsulating both magnetic nanobeads and living cellsat thesame time, and(4) self-assembling the magnetic-active hydrogel micro-structuresby applying an external magnetic field.
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Report
(3 results)
Research Products
(11 results)
