Construction of a Nitrogenase Model Using Metal Cluster-Containing Metallothionein
| Project/Area Number |
22655017
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Inorganic chemistry
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| Research Institution | Osaka University |
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Principal Investigator |
HAYASHI Takashi 大阪大学, 大学院・工学研究科, 教授 (20222226)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,520,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥1,700,000 (Direct Cost: ¥1,700,000)
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| Keywords | タンパク質 / 酵素 / 鉄硫黄クラスター / 触媒 |
|---|
| Research Abstract |
The reduction of hydrazine derivatives by a synthetic metallothionein complex with iron ions was monitored. Particularly, the complex is found to bring about the reductive N-N bond cleavage of methyl red smoothly. In addition, the functional model of hydrogenase with iron-sulfur cluster was also prepared by the conjugation between apocytochrome c matrix and iron-carbonyl cluster. The obtained complex exhibits the hydrogenase activity toward the H2 generation in aqueous media.
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Report
(3 results)
Research Products
(17 results)
