Development of a cell microarray chip for evaluating invasion of cancer cells by transfer printing of transfected cells
Project/Area Number |
22656189
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Single-year Grants |
Research Field |
Biofunction/Bioprocess
|
Research Institution | The University of Tokyo |
Principal Investigator |
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥3,560,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,000,000 (Direct Cost: ¥2,000,000)
|
Keywords | 細胞マイクロアレイ / 癌細胞 / 浸潤 / 細胞転写 / PEG脂質 / コラーゲンシート / 癌 / 細胞アレイ / 機能性核酸 / MMP / FRET |
Research Abstract |
We developed a method that can print a microarray of transfected cells from a glass substrate onto a hydrogel, and by using this method, microarrays of transfected cancer cells were successfully prepared in a three-dimensional extracellular matrix gel and employed for evaluating the anti-invasion activities of siRNA under an in vivo-like environment.
|
Report
(3 results)
Research Products
(10 results)