Searching new functions of silk gland for detoxication, excretion, and immunity
Project/Area Number |
22658020
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Single-year Grants |
Research Field |
Applied entomology
|
Research Institution | National Institute of Agrobiological Sciences |
Principal Investigator |
KAMIMURA Manabu 独立行政法人農業生物資源研究所, 昆虫成長制御研究ユニット, 主任研究員 (60370649)
|
Co-Investigator(Kenkyū-buntansha) |
HIRAYAMA Chikara 独立行政法人農業生物資源研究所, 昆虫機能研究開発ユニット, 主任研究員 (90370676)
|
Co-Investigator(Renkei-kenkyūsha) |
ISHIBASHI Jun (独)農業生物資源研究所, 昆虫機能研究開発ユニット, 主任研究員 (20391576)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥3,730,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,000,000 (Direct Cost: ¥1,000,000)
|
Keywords | 昆虫生理 / 絹糸腺 / 繭 / 解毒 / 排泄 / 免疫 |
Research Abstract |
The silkworm larvae that ate an artificial diet containing a dye span colorful cocoons, indicating that the silk gland can excrete unnecessary materials into cocoons. Microarray and RT-PCR analysis showed that multiple transporter genes are strongly expressed in the Malpighian tubes until the mid-last instar and thereafter expressed strongly in the anterior silk gland. Taken together, these results suggest that the silk gland functions as "pupation stage-specific excretory organ." In contrast, we could not obtain an evidence that show immune functions of the silk gland.
|
Report
(4 results)
Research Products
(7 results)