Clarification of immunity system of high disease resistance with the use of genetically selected mice for high immunity and immunoactive agent
| Project/Area Number |
22658080
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Tohoku University |
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Principal Investigator |
SUZUKI Keiichi 東北大学, 大学院・農学研究科, 教授 (10344706)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,520,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥1,700,000 (Direct Cost: ¥1,700,000)
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| Keywords | マウス / 免疫能 / 選抜 / 甘草 / 抗病性 / 免疫 / 免疫活性物質 |
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| Research Abstract |
Feed to which the licorice was added is give to the 3 lines of mice selected for high peripheral blood immunity and non-selected control line of mice, and the combination effect of genetic line of mice and licorice addition was compared measuring various immunities. Addition of the licorice to feed suggested the control of an excessive immune response of phagocyte activity, and an early response and prompt returning to the normal situation of IgM. In addition, when the licorice was given, the IL-2 expression was suppressed only in the mice of N line. This result suggested that the immune-modulatory function of licorice exists corresponding to the line of mice.
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Report
(3 results)
Research Products
(6 results)
