| Project/Area Number |
22658087
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied animal science
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| Research Institution | National Institute of Radiological Sciences |
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Principal Investigator |
TSUKAMOTO Satoshi 独立行政法人放射線医学総合研究所, 研究基盤センター, 技術員 (80510693)
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| Research Collaborator |
MINAMI Naojiro 京都大学, 農学研究科, 准教授 (30212236)
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,550,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥1,600,000 (Direct Cost: ¥1,600,000)
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| Keywords | オートファジー / ミトコンドリア / 精子 / 受精卵 / マウス |
|---|
| Research Abstract |
The aim of our study is whether autophagy is involved in the sperm mitochondria degradation in mouse embryos. We showed that degradation of sperm mitochondria normally occurred in the absence of autophagy, indicating the possibility that other degradation pathway could be involved in the sperm mitochondria degradation.
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