| Project/Area Number |
22659068
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Pathological medical chemistry
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| Research Institution | Osaka University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAGAI Ryoji 日本女子大学, 家政学部, 講師 (20315295)
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,090,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | 糖尿病 / 動脈硬化 / AGE / シグナル増幅反応 / 非侵襲検査 / AGEs / メイラード反応 / CML / 糖化 / ビオチンダイマー / ストレプトアビジン重合体形成 / ビオチントリマー |
|---|
| Research Abstract |
The very-small-quantity protein of the 1 molecular level was detected by the" signal repetition amplifying method" to which each makes two crosslinking agents which have a bridge construction relation react by turns. Condition examination for detecting efficiently the Maillard reaction products for geriatric diseases was performed, and shortening of detection time was realized.
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