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Analysis of evidence-practice gap using healthcare claims(receipts) database : with special reference to implementation of the recommendations in the clinical practice guidelines and adherence to the alert in package insert.

Research Project

Project/Area Number 22659102
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Medical sociology
Research InstitutionKyoto University

Principal Investigator

NAKAYAMA Takeo  京都大学, 大学院・医学研究科, 教授 (70217933)

Co-Investigator(Renkei-kenkyūsha) ISHIZAKI Tatsuro  東京都健康長寿医療センター, 東京都健康長寿医療センター研究所, 研究部長 (30246045)
HIGASHI Takahiro  東京大学, 医学系研究科, 准教授 (10402851)
NODA Mitsuhiko  独立行政法人国立国際医療研究センタ-研究所, 糖尿病研究連携部, 部長 (90237850)
MIYAZAKI Kikuko  京都大学, 医学研究科, 助手 (70464229)
SATOU Toshihiko  北里大学, 医学部, 教授 (10225972)
IKEDA Shunya  国際医療福祉大学, 薬学部, 教授 (90193200)
Research Collaborator SUZUKI Hiromichi  財団法人国際医学情報センター, 主席研究員 (50524089)
Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥2,700,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,400,000 (Direct Cost: ¥1,400,000)
KeywordsJ医療の質
Research Abstract

In recent years, the problem of underuse of useful clinical evidence is coming to be important-evidence-practice gap. The major concern about evidence-practice gap is insufficient implementation of evidence-based effective treatment, however, the perspective can be extended to measures to improve drug safety and prevention of drug related adverse events. At first, this study characterized the database of receipt(healthcare claims) and the usefulness for research purpose. Afterwards, two cases(implementation of recommendation of preventive drug use against steroid-induced osteoporosis, adherence to the alert indicated in revised package insert for ergot-derived anti-Parkinson drugs, of which risk of valvulopathy has been identified) were examined using this database. Through these analyses, the receipt database was proved to be useful to study evidence-practice gap.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (12 results)

All 2012 2011 2010 Other

All Journal Article (7 results) (of which Peer Reviewed: 6 results) Presentation (4 results) Remarks (1 results)

  • [Journal Article] Approaching “Evidence-Practice Gap” for Pharmaceutical Risk Management: From the View of Analysis of Healthcare Claim Data2012

    • Author(s)
      中山健夫
    • Journal Title

      YAKUGAKU ZASSHI

      Volume: 132 Issue: 5 Pages: 549-554

    • DOI

      10.1248/yakushi.132.549

    • NAID

      130001888669

    • ISSN
      0031-6903, 1347-5231
    • Year and Date
      2012-05-01
    • Related Report
      2011 Final Research Report
  • [Journal Article] Adherence in performing echocardiography to detect valvulopathy associated with the use of ergot-derived dopamine agonists in patients with Parkinson's disease2011

    • Author(s)
      Nakaoka S, Ishizaki T, Urushibara H, Sato t, Ikeda S, Noda M, Morikawa K, Nakayama T.
    • Journal Title

      Internal Medicine

      Volume: 50(7) 3 Pages: 687-94

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Management and Treatment of Osteoporosis in Patients Receiving Long-term Glucocorticoid Treatment: Current Status of Adherence to Clinical Guidelines and Related Factors2011

    • Author(s)
      Kirigaya D, Nakayama T, Ishizaki T, Ikeda S, Sato T
    • Journal Title

      Internal Medicine

      Volume: 50 Issue: 22 Pages: 2793-2800

    • DOI

      10.2169/internalmedicine.50.5266

    • NAID

      130001288667

    • ISSN
      0918-2918, 1349-7235
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Echocardiography for the Detection of Valvulopathy Associated with the Use of Ergot-Derived Dopamine Agonists in Patients with Parkinson's Disease2011

    • Author(s)
      Nakaoka S, Ishizaki T, Urushibara H, Sato T, Ikeda S, Noda M, Morikawa K, Nakayama T
    • Journal Title

      Internal Medicine

      Volume: 50 Issue: 7 Pages: 687-694

    • DOI

      10.2169/internalmedicine.50.4344

    • NAID

      130000650040

    • ISSN
      0918-2918, 1349-7235
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a Database of Health Insurance Claims : Standardization of Disease Classifications and Anonymous Record Linkage.2011

    • Author(s)
      Kimura S, Sato T, Ikeda S, Noda M, Nakayama T
    • Journal Title

      Journal of Epidemiology

      Volume: 20(5) Pages: 413-9

    • NAID

      10027651661

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a Database of Health Insurance Claims: Standardization of Disease Classifications and Anonymous Record Linkage2010

    • Author(s)
      Kimura S, Sato T, Ikeda S, Noda M, Nakayama T.
    • Journal Title

      Journal of Epidemiology

      Volume: 20 Issue: 5 Pages: 413-419

    • DOI

      10.2188/jea.JE20090066

    • NAID

      10027651661

    • ISSN
      0917-5040, 1349-9092
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Adherence in performing echocardiography to detect valvulopathy associated with the use of ergot-derived dopamine agonists in patients with Parkinson's disease.

    • Author(s)
      Nakaoka S, Ishizaki T, Urushibara H, Sato T, Ikeda S, Noda M, Morikawa K, Nakayama T
    • Journal Title

      Internal Medicine

      Volume: (In Press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] 薬剤疫学とリスクコミュニケーション2011

    • Author(s)
      中山健夫
    • Organizer
      第17回日本薬剤疫学会(招待講演)
    • Place of Presentation
      慶応義塾大学薬学部(東京都)
    • Year and Date
      2011-11-06
    • Related Report
      2011 Final Research Report
  • [Presentation] 薬剤疫学とリスクコミュニケーション2011

    • Author(s)
      中山健夫
    • Organizer
      第17回日本薬剤疫学会
    • Place of Presentation
      慶應義塾大学薬学部(東京都)(招待講演)
    • Year and Date
      2011-11-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] 10 years history of CPGs(Clinical Practice Guidelines) development in Japan2011

    • Author(s)
      Suzuki H, Nakayama T, Tsutani K
    • Organizer
      The 7th Guidelines Internet Network Conference
    • Place of Presentation
      Chicago Marriott Downtown(USA)
    • Year and Date
      2011-08-25
    • Related Report
      2011 Final Research Report
  • [Presentation] 10 years history of CPGs (Clinical Practice Guidelines) development in Japan2010

    • Author(s)
      Hiromichi Suzuki, Takeo Nakayama, Kiichiro Tsutani
    • Organizer
      第7回Guidelines Internet Network Conference
    • Place of Presentation
      Chicago Marriott Down-Town (USA)
    • Related Report
      2010 Annual Research Report
  • [Remarks] 保健医療情報分析活用研究会

    • URL

      http://reseken.umin.ne.jp/

    • Related Report
      2011 Final Research Report

URL: 

Published: 2010-08-23   Modified: 2016-04-21  

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