• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Analysis of the pathogenesis of allergic rhinitis originated by epithelial cells

Research Project

Project/Area Number 22659187
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field 膠原病・アレルギー・感染症内科学
Research InstitutionHyogo Medical University

Principal Investigator

YOSHIMOTO Tomohiro  兵庫医科大学, 医学部, 教授 (60241171)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,190,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,500,000 (Direct Cost: ¥1,500,000)
Keywords上皮細胞 / 鼻炎 / アレルギー / サイトカイン / 好塩基球 / アレルゲン
Research Abstract

Allergic rhinitis often develop even in people without atopic disposition during pollen season as well as people with a predisposition to atopy. Divided into two types, it was named "atopic allergic rhinitis" and "sudden-onset allergic rhinitis", respectively. In this study, we established above two types of mouse model of ragweed pollen-specific allergic rhinitis, and analyzed the mechanism of its onset. As a result, we revealed that both pollen grains-deriven IL-33 from nasal mucosa epithelial cells and the FcεR1 positive cells(mast cells and basophils) play an important role in the pathogenesis of pollen-specific allergic rhinitis.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (97 results)

All 2012 2011 2010

All Journal Article (38 results) (of which Peer Reviewed: 10 results) Presentation (51 results) Book (4 results) Patent(Industrial Property Rights) (4 results)

  • [Journal Article] A critical role of IL-33 in experimental allergic rhinitis2012

    • Author(s)
      Haenuki Y, Matsushita K, Futatsugi-Yumikura S, Ishii KJ, Kawagoe T, Imoto Y, Fujieda S, Yasuda M, Hisa Y, Akira S, Nakanishi K, Yoshimoto T
    • Journal Title

      J Allergy Clin Immunol

      Volume: (in press) Issue: 1 Pages: 184-194

    • DOI

      10.1016/j.jaci.2012.02.013

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Contribution of IL-33-activated type II innate lymphoid cells to pulmonary eosinophilia in intestinal nematode-infected mice2012

    • Author(s)
      Yasuda K, Yoshimoto T, et al.(他11人, 11番)
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 109 Pages: 3451-56

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 新しいアレルギーへの招待2011

    • Author(s)
      善本知広
    • Journal Title

      兵庫医科大学医学会雑誌

      Volume: 36 Pages: 27-36

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Journal Article] 好塩基球によるTh2細胞誘導機序2011

    • Author(s)
      善本知広
    • Journal Title

      IgE practice in asthma

      Pages: 2-7

    • Related Report
      2011 Final Research Report
  • [Journal Article] ブタクサ花粉特異的アレルギー性結膜炎モデルマウスの作製と結膜炎に対するIL-33の病因的役割2011

    • Author(s)
      善本知広
    • Journal Title

      アレルギー

      Volume: 60 Pages: 16-25

    • NAID

      110008440532

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Journal Article] IL-33とアレルギー2011

    • Author(s)
      善本知広
    • Journal Title

      アレルギー・免疫

      Volume: 18 Pages: 424-435

    • NAID

      40016259729

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Journal Article] 上皮細胞由来サイトカインとアレルギー2011

    • Author(s)
      善本知広
    • Journal Title

      アレルギー・免疫

      Volume: 18 Pages: 483-485

    • Related Report
      2011 Final Research Report
  • [Journal Article] 自然型アレルギーと獲得型アレルギー2011

    • Author(s)
      善本知広
    • Journal Title

      アレルギー・免疫

      Volume: 18 Pages: 483-485

    • NAID

      40021263728

    • Related Report
      2011 Final Research Report
  • [Journal Article] アレルギー性結膜炎:アレルギー性結膜炎とIL-332011

    • Author(s)
      松葉沙織, 善本知広
    • Journal Title

      アレルギー・免疫

      Volume: 18 Pages: 50-64

    • Related Report
      2011 Final Research Report
  • [Journal Article] アレルギーを科学して,アレルギーを治す2011

    • Author(s)
      善本知広
    • Journal Title

      アレルギー・免疫

      Volume: 18 Pages: 317-318

    • Related Report
      2011 Final Research Report
  • [Journal Article] 特集:免疫学からみたアレルギー1~アレルギー疾患モデルマウス~アレルギーを科学して,アレルギーを治す2011

    • Author(s)
      善本知広
    • Journal Title

      アレルギー・免疫

      Volume: 18 Pages: 317-318

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 特集:免疫学からみたアレルギー1~アレルギー疾患モデルマウス~アレルギー性結膜炎:アレルギー性結膜炎とIL-332011

    • Author(s)
      松葉沙織, 善本知広
    • Journal Title

      アレルギー・免疫

      Volume: 18 Pages: 50-64

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 特集:免疫学からみたアレルギー2~アレルギー担当細胞と誘導・制御分子~自然型アレルギーと獲得型アレルギー2011

    • Author(s)
      善本知広
    • Journal Title

      アレルギー・免疫

      Volume: 18 Pages: 483-485

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 特集:免疫学からみたアレルギー~アレルギー担当細胞と誘導・制御分子~上皮細胞由来サイトカインとアレルギー2011

    • Author(s)
      善本知広
    • Journal Title

      アレルギー・免疫

      Volume: 18 Pages: 486-505

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 好塩基球によるTh2細胞誘導機序2011

    • Author(s)
      善本知広, 中西憲司
    • Journal Title

      IgE practice in asthma

      Volume: October Pages: 2-7

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Importance of IL-18-induced Super Th1 cells for the development of allergic inflammation2010

    • Author(s)
      Nakanishi K, Tsutsui H, Yoshimoto T.
    • Journal Title

      Allergol Int

      Volume: 59 Pages: 137-141

    • NAID

      10029670054

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Basophils as Th2-inducing antigen-presenting cells2010

    • Author(s)
      Yoshimoto T.
    • Journal Title

      Int Immunol

      Volume: 22 Pages: 543-550

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Crucial role of impaired Kupffer cell phagocytosis on the decreased Sonazoid-enhanced echogenicity in a liver of a non-alchoholic steatohepatitis rat model2010

    • Author(s)
      Yoshikawa S, Yoshimoto T, et al.(他12人, 6番)
    • Journal Title

      Hepato-logy Research

      Volume: 40 Pages: 823-831

    • NAID

      10026595516

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Contribution of IL-33 to induction and augmentation of experimental allergic conjunctivitis2010

    • Author(s)
      Matsuba-Kitamura S, Yoshimoto T, Yasuda K, Futatsugi-Yumikura S, Taki Y, Muto T, Ikeda T, Mimura O, Nakanishi K.
    • Journal Title

      Int Immunol

      Volume: 22 Pages: 479-489

    • NAID

      10027580386

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 腹腔内術後癒着形成におけるIFN-γの重要性2010

    • Author(s)
      小坂久, 善本知広, 中西憲司, 藤元治朗
    • Journal Title

      炎症と免疫

      Volume: 18 Pages: 531-37

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Journal Article] 自然免疫系細胞からのサイトカインとアレルギー2010

    • Author(s)
      善本知広
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 54 Pages: 271-86

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Journal Article] 疾患からみたサイトカイン:IL-332010

    • Author(s)
      善本知広
    • Journal Title

      分子リウマチ治療

      Volume: 3 Pages: 219-24

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Journal Article] サイトカインと疾患:Th2細胞分化と好塩基球2010

    • Author(s)
      善本知広
    • Journal Title

      医学のあゆみ

      Volume: 234 Pages: 411-8

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Journal Article] サイトカインと疾患:IL-33とアレルギー性疾患2010

    • Author(s)
      善本知広
    • Journal Title

      医学のあゆみ

      Volume: 234 Pages: 511-7

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Journal Article] アレルギーとIL-18/IL-332010

    • Author(s)
      善本知広, 中西憲司
    • Journal Title

      実験医学

      Volume: 28 Pages: 167-73

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Journal Article] 術後腸管癒着とサイトカイン2010

    • Author(s)
      善本知広
    • Journal Title

      実験医学

      Volume: 28(増刊) Pages: 207-12

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Journal Article] IL-33の生理機能2010

    • Author(s)
      善本知広
    • Journal Title

      呼吸

      Volume: 29 Pages: 364-72

    • Related Report
      2011 Final Research Report
  • [Journal Article] Super Th1細胞とアレルギー2010

    • Author(s)
      善本知広
    • Journal Title

      International Review of Asthma & COPD

      Volume: 12 Pages: 27-34

    • Related Report
      2011 Final Research Report
  • [Journal Article] 好塩基球による抗原提示とアレルギー2010

    • Author(s)
      善本知広
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 53 Pages: 301-11

    • NAID

      40017058244

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Journal Article] 好塩基球の新たな機能-アレルギー誘導抗原提示細胞-2010

    • Author(s)
      善本知広
    • Journal Title

      医学のあゆみ

      Volume: 232 Pages: 285-86

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Journal Article] 好塩基球によるTh2細胞の誘導と増強2010

    • Author(s)
      善本知広
    • Journal Title

      炎症と免疫

      Volume: 18 Pages: 14-22

    • Related Report
      2011 Final Research Report
  • [Journal Article] Contribution of IL-33 to induction and augmentation of experimental allergic conjunctivitis.2010

    • Author(s)
      Matsuba-Kitamura S, Yoshimoto T, Yasuda K, Futatsugi-Yumikura S, Taki Y, Muto T, Ikeda T, Mimura O, Nakanishi K.
    • Journal Title

      Int Immunol

      Volume: 22 Pages: 479-89

    • NAID

      10027580386

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Crucial role of impaired Kupffer cell phagocytosis on the decreased Sonazoid-enhanced echogenicity in a liver of a nonalchoholic steatohepatitis rat model.2010

    • Author(s)
      Yoshikawa S, Iijima H, Saito M, Tanaka H, Imanishi H, Yoshimoto N, Yoshimoto T, Futatsugi-Yumikura S, Nakanishi K, Tsujimura T, Nishigami T, Kudo A, Nishiguchi S
    • Journal Title

      Hepatology Research

      Volume: 40 Pages: 823-31

    • NAID

      10026595516

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Basophils as Th2-inducing antigen-presenting cells.2010

    • Author(s)
      Yoshimoto T.
    • Journal Title

      Int Immunol

      Volume: 22 Pages: 543-50

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Importance of IL-18-induced Super Th1 cells for the development of allergic inflammation.2010

    • Author(s)
      Nakanishi K, Tsutsui H, Yoshimoto T.
    • Journal Title

      Allergol Int

      Volume: 59 Pages: 137-41

    • NAID

      10029670054

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 好塩基球によるTH2細胞の誘導と増強2010

    • Author(s)
      善本知広
    • Journal Title

      炎症と免疫

      Volume: 18 Pages: 14-22

    • Related Report
      2010 Annual Research Report
  • [Journal Article] スーパーTh1細胞とアレルギー2010

    • Author(s)
      善本知広
    • Journal Title

      International Review of Asthma & COPD

      Volume: 12 Pages: 27-34

    • Related Report
      2010 Annual Research Report
  • [Journal Article] IL-33の生理作用2010

    • Author(s)
      善本知広
    • Journal Title

      呼吸

      Volume: 29 Pages: 364-72

    • Related Report
      2010 Annual Research Report
  • [Presentation] アレルギー性鼻炎の新しい発症メカニズム:花粉-IL-33-マスト細胞/好塩基球による鼻粘膜免疫機構2011

    • Author(s)
      善本知広
    • Organizer
      第32回和漢医薬学総合研究所特別セミナー「和漢薬治療のターゲットとしての粘膜免疫機構」
    • Place of Presentation
      金沢
    • Year and Date
      2011-12-09
    • Related Report
      2011 Final Research Report
  • [Presentation] アレルギー性鼻炎の新しい発症メカニズム:花粉-IL-33-マスト細胞/好塩基球による鼻粘膜免疫機構2011

    • Author(s)
      善本知広
    • Organizer
      第32回和漢医薬学総合研究所特別セミナー「和漢薬治療のターゲットとしての粘膜免疫機構」
    • Place of Presentation
      富山(招待講演)
    • Year and Date
      2011-12-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] Contribution of IL-33 activated natural helper/nuocyte-like cells to IL-5 production and eosinophil accumulation in intestinal nematode in fected mice2011

    • Author(s)
      Yasuda K, Muto T, Imai Y, Matsumoto M, Sasaki Y, Taki Y, Futatsugi-Yumikura S, Yoshimoto T, Nakanishi K
    • Organizer
      第40回日本免疫学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2011-11-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] Antibody-mediated expulsion of Strongyloides venezuelensis2011

    • Author(s)
      Matsumoto M, Sasaki Y, Yasuda K, Muramatsu M, Honjo T, Yoshimoto T, Nakanishi K
    • Organizer
      第40回日本免疫学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2011-11-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] ブタクサ花粉特異的アレルギー性鼻炎モデルマウスにおけ2るマスト細胞/好塩基球とIL-33の病因的役割2011

    • Author(s)
      萠抜陽子, 弓倉(二木)静英, 松下一史, 安田誠, 久育男, 中西憲司, 善本知広
    • Organizer
      第40回日本免疫学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2011-11-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] アレルギー増悪機構-好塩基球の抗原提示能について2011

    • Author(s)
      善本知広
    • Organizer
      第12回緑尼会学術講演会
    • Place of Presentation
      尼崎
    • Year and Date
      2011-11-19
    • Related Report
      2011 Final Research Report
  • [Presentation] IL-33とアレルギー2011

    • Author(s)
      善本知広
    • Organizer
      第61回日本アレルギー学会秋季学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-11
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] アレルキー性鼻炎におけるマスト細胞/好塩基球の役割2011

    • Author(s)
      萠抜陽子, 善本知広
    • Organizer
      第61回日本アレルギー学会秋季学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] IL-33とアレルキー性結膜炎2011

    • Author(s)
      松葉(北村)沙織, 善本知広
    • Organizer
      第61回日本アレルギー学会秋季学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヴェネズエラ糞線虫に対する抗体依存性排除機構について2011

    • Author(s)
      松本真琴, 佐々木由紀, 安田好文, 村松正道, 本庶佑, 善本知広, 中西憲司
    • Organizer
      第67回日本寄生虫学会西日本支部大会
    • Place of Presentation
      金沢
    • Year and Date
      2011-10-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] アレルギー増悪機構-好塩基球の抗原提示能について-2011

    • Author(s)
      善本知広
    • Organizer
      第37回兵庫県臨床アレルギー研究会
    • Place of Presentation
      神戸
    • Year and Date
      2011-10-15
    • Related Report
      2011 Final Research Report
  • [Presentation] アレルギー増悪機構-好塩基球の抗原提示能について-2011

    • Author(s)
      善本知広
    • Organizer
      第37回兵庫県臨床アレルギー研究会
    • Place of Presentation
      神戸(招待講演)
    • Year and Date
      2011-10-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] アレルギー増悪機構の基礎からの解析-好塩基球の抗原提示機能-2011

    • Author(s)
      善本知広
    • Organizer
      第29回呼吸器・免疫シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2011-10-01
    • Related Report
      2011 Final Research Report
  • [Presentation] アレルギー増悪機構の基礎からの解析-好塩基球の抗原提示機能-2011

    • Author(s)
      善本知広
    • Organizer
      第29回呼吸器・免疫シンポジウム
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-10-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] アレルギーの基礎とアレルギー研究の最前線2011

    • Author(s)
      善本知広
    • Organizer
      第152回日本獣医学会
    • Place of Presentation
      大阪
    • Year and Date
      2011-09-20
    • Related Report
      2011 Final Research Report
  • [Presentation] アレルギーの基礎とアレルギー研究の最前線2011

    • Author(s)
      善本知広
    • Organizer
      第152回日本獣医学会
    • Place of Presentation
      大阪(招待講演)
    • Year and Date
      2011-09-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] IL-33と疾患2011

    • Author(s)
      善本知広
    • Organizer
      第39回日本臨床免疫学会総会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] Strongyloides venezuelensisの感染防御における好酸球と好塩基球の役割について2011

    • Author(s)
      松本真琴, 安田好文, 善本知広, 中西憲司
    • Organizer
      第80回日本寄生虫学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-07-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] IL-33 mediated expulsion of Nippostrongylus brasiliensis and Strongyloides venezuelensis2011

    • Author(s)
      安田好文, 佐々木由紀, 松本真琴, 高城ゆう子, 善本知広, 中西憲司
    • Organizer
      第80回日本寄生虫学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-07-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] IL-27トランスジェニックマウスではDNFBの接触過敏症が減弱している2011

    • Author(s)
      今井康友, 善本知広, 善本隆之, 中西憲司, 山西清文
    • Organizer
      第41回日本接触皮膚炎学会
    • Place of Presentation
      甲府
    • Year and Date
      2011-07-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] IFN-γ is a therapeutic target molecule for prevention of postoperative adhesion formation2011

    • Author(s)
      Yoshimoto T.
    • Organizer
      The 19th International Symposium on Molecular Cell Biology of Macrophages 2011 : Cytokines/Chemokines, Immunity, and Diseases
    • Place of Presentation
      Osaka
    • Year and Date
      2011-05-26
    • Related Report
      2011 Final Research Report
  • [Presentation] IL-33 mediated expulsion of Nippostrongylus brasiliensis and Strongyloides venezuelensis2011

    • Author(s)
      Yasuda K, Sasaki Y, Matsumoto M, Taki Y, Yoshimoto T, Nakanishi K.
    • Organizer
      The 19th International Symposium on Molecular Cell Biology of Macrophages 2011 : Cytokines/Chemokines, Immunity, and Diseases
    • Place of Presentation
      Osaka
    • Year and Date
      2011-05-26
    • Related Report
      2011 Final Research Report
  • [Presentation] Basophils are essential for rapidly expelling Strongyloides venezuelensis2011

    • Author(s)
      Matsumoto M, Yasuda K, Kubo M, Yoshimoto T, Nakanishi K.
    • Organizer
      The 19th International Symposium on Molecular Cell Biology of Macrophages 2011 : Cytokines/Chemokines, Immunity, and Diseases
    • Place of Presentation
      Osaka
    • Year and Date
      2011-05-26
    • Related Report
      2011 Final Research Report
  • [Presentation] IFN-γ is a therapeutic target molecule for prevention of postoperative adhesion formation2011

    • Author(s)
      Yoshimoto T
    • Organizer
      The 19th International Symposium on Molecular Cell Biology of Macrophages 2011
    • Place of Presentation
      Osaka(招待講演)
    • Year and Date
      2011-05-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] IL-33 mediated expulsion of Nippostrongylus brasiliensis and Strongyloides venezuelensis2011

    • Author(s)
      Yasuda K, Sasaki Y, Matsumoto M, Taki Y, Yoshimoto T, Nakanishi K
    • Organizer
      The 19th International Symposium on Molecular Cell Biology of Macrophages 2011
    • Place of Presentation
      Osaka
    • Year and Date
      2011-05-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] Basophils are essential for rapidly expelling Strongyloides venezuelensis2011

    • Author(s)
      Matsumoto M, Yasuda K, Kubo M, Yoshimoto T, Nakanishi K
    • Organizer
      The 19th International Symposium on Molecular Cell Biology of Macrophages 2011
    • Place of Presentation
      Osaka
    • Year and Date
      2011-05-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] Role of IL-33 in experimental allergic conjunctivitis2011

    • Author(s)
      Yoshimoto T, Matsuba-Kitamura S, Nakanishi K.
    • Organizer
      Keystone Symposia Mucosal Biology : A Fine Balance between Tolerance and Immunity
    • Place of Presentation
      Canada
    • Year and Date
      2011-02-28
    • Related Report
      2011 Final Research Report
  • [Presentation] 好塩基球は抗原提示細胞としてTh2細胞を誘導/増強する2010

    • Author(s)
      善本知広
    • Organizer
      第60回日本アレルギー学会秋季学術集会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Strongyloides venezuelensisの感染防御における好酸球と好塩基球の役割について2010

    • Author(s)
      松本真琴, 安田好文, 久保允人, 善本知広, 中西憲司.
    • Organizer
      第66回日本寄生虫学会西日本支部大会
    • Place of Presentation
      岡山
    • Year and Date
      2010-11-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] 喘息増悪に関する好塩基球の関与について2010

    • Author(s)
      善本知広
    • Organizer
      ノバルティスファーマ社外講師勉強会
    • Place of Presentation
      東京
    • Year and Date
      2010-11-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] Role of IL-33 in experimental allergic conjunctivitis2010

    • Author(s)
      Yoshimoto T, Matsuba-Kitamura S, Yasuda K, Futatsugi-Yumikura S, Matsushita K, Nakanishi K.
    • Organizer
      4^<th> International Symposium on Molecular Allergology(ISMA2010)
    • Place of Presentation
      Germany
    • Year and Date
      2010-10-30
    • Related Report
      2011 Final Research Report
  • [Presentation] Role of IL-33 in experimental allergic conjunctivitis.2010

    • Author(s)
      Yoshimoto T, Matsuba-Kitamura S, Yasuda K, Futatsugi-Yumikura S, Matsushita K, Nakanishi K.
    • Organizer
      4^<th> International Symposium on Molecular Allergology
    • Place of Presentation
      Munich, Germany
    • Year and Date
      2010-10-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新しいアレルギーの概念:好塩基球によるTh2細胞の誘導2010

    • Author(s)
      善本知広
    • Organizer
      第10回愛知免疫アレルギーを語る会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-09-11
    • Related Report
      2011 Final Research Report
  • [Presentation] 新しいアレルギーの概念:好塩基球によるTh2細胞の誘導2010

    • Author(s)
      善本知広
    • Organizer
      第10回愛知免疫アレルギー
    • Place of Presentation
      名古屋
    • Year and Date
      2010-09-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] Basophils play a pivotal role in the expression of gastrointestinal nematode Strongyloides venezuelensis.2010

    • Author(s)
      Mastumoto M, Yasuda, K, Kubo M, Yoshimoto T, Nakanishi K.
    • Organizer
      14^<th> International congress of Immunology
    • Place of Presentation
      Kobe
    • Year and Date
      2010-08-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] IL-33 mediated expulsion of Nippostrongylus brasiliensis in the absence of adaptive immune system.2010

    • Author(s)
      Yasuda K, Sasaki Y, Kondo Y, Matsumoto M, Yoshimoto T, Nakanishi K.
    • Organizer
      14^<th> International congress of Immunology
    • Place of Presentation
      Kobe
    • Year and Date
      2010-08-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Basophils contribute to TH2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells.2010

    • Author(s)
      Yoshimoto T, Yasuda, K, Tanaka H, Nakanishi K.
    • Organizer
      14^<th> International congress of Immunology
    • Place of Presentation
      Kobe
    • Year and Date
      2010-08-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Basophils contribute to TH2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+T cells2010

    • Author(s)
      Yoshimoto T, Yasuda, K, Tanaka H, Nakanishi K.
    • Organizer
      (Work shop) 14^<th> International congress of Immunology
    • Place of Presentation
      Kobe
    • Year and Date
      2010-08-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Basophils play a pivotal role in the expression of gastrointestinal nematode Strongyloides venezuelensis2010

    • Author(s)
      Mastumoto M, Yasuda, K, Kubo M, Yoshimoto T, Nakanishi K.
    • Organizer
      (Work shop) 14^<th> International congress of Immunology
    • Place of Presentation
      Kobe
    • Year and Date
      2010-08-24
    • Related Report
      2011 Final Research Report
  • [Presentation] IL-33 mediated expulsion of Nippostrongylus brasiliensis in the absence of adaptive immune system2010

    • Author(s)
      Yasuda K, Sasaki Y, Kondo Y, Matsumoto M, Yoshimoto T, Nakanishi K.
    • Organizer
      14^<th> International congress of Immunology
    • Place of Presentation
      Kobe
    • Year and Date
      2010-08-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Contribution of IL-33 to induction and augmentation of experimental allergic conjunctivitis2010

    • Author(s)
      Matsuba-Kitamura S, Yoshimoto T, Yasuda K, Futatsugi-Yumikura S, Taki Y, Muto T, Ikeda T, Mimura O, Nakanishi K.
    • Organizer
      14^<th> International congress of Immunology
    • Place of Presentation
      Kobe
    • Year and Date
      2010-08-24
    • Related Report
      2011 Final Research Report
  • [Presentation] A novel type of CD5-positive lpr cells of Fas-deficient mice in Balb/c background with allergic blepharitis stimulate IgE production2010

    • Author(s)
      Takahashi S, Futatsugi-Yumikura S, Yoshimoto T, Yonehara S, Nakanishi K
    • Organizer
      14^<th> International congress of Immunology
    • Place of Presentation
      Kobe
    • Year and Date
      2010-08-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Contribution of IL-33 to induction and augmentation of experimental allergic conjunctivitis.2010

    • Author(s)
      Matsuba-Kitamura S, Yoshimoto T, Yasuda K, Futatsugi-Yumikura S, Taki Y, Muto T, Ikeda T, Mimura O, Nakanishi K.
    • Organizer
      14^<th> International congress of Immunology
    • Place of Presentation
      Kobe
    • Year and Date
      2010-08-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] A novel type of CD5-positive lpr cells of Fas-deficient mice in Balb/c background with allergic blepharitis stimulate IgE production.2010

    • Author(s)
      Takahashi S, Futatsugi-Yumikura S, Yoshimoto T, Yonehara S, Nakanishi K.
    • Organizer
      14^<th> International congress of Immunology
    • Place of Presentation
      Kobe
    • Year and Date
      2010-08-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] 免疫・アレルギー疾患への挑戦:From clinic to bench and back2010

    • Author(s)
      善本知広
    • Organizer
      第5回NIH東海in Japan
    • Place of Presentation
      名古屋
    • Year and Date
      2010-07-16
    • Related Report
      2011 Final Research Report
  • [Presentation] 免疫・アレルギー疾患への挑戦:From clinic to bench and back.2010

    • Author(s)
      善本知広
    • Organizer
      第5回NIH東海in Japan
    • Place of Presentation
      名古屋
    • Year and Date
      2010-07-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新しいアレルギーの概念:A new concept of Allergy.2010

    • Author(s)
      善本知広
    • Organizer
      神戸大学大学院 先端医学トピックス
    • Place of Presentation
      神戸
    • Year and Date
      2010-07-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] 好塩基球の新たな機能;Th2細胞誘導抗原提示細胞2010

    • Author(s)
      善本知広
    • Organizer
      第75回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      北九州
    • Year and Date
      2010-06-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] 腸管寄生線虫によって増加する好塩基球の抗原提示能と選択的Th2細胞誘導機能2010

    • Author(s)
      善本知広, 安田好文, 弓倉(二木)静英, 松本真琴, 中西憲司.
    • Organizer
      第79回日本寄生虫学会大会
    • Place of Presentation
      旭川
    • Year and Date
      2010-05-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] ブタクサ花粉特異的アレルギー性結膜炎モデルマウスの作製と結膜炎に対するIL-33の病因的役割2010

    • Author(s)
      善本知広
    • Organizer
      第22回日本アレルギー学会春季臨床大会
    • Place of Presentation
      京都
    • Year and Date
      2010-05-08
    • Related Report
      2010 Annual Research Report
  • [Presentation] Basophils contribute to TH2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+T cells2010

    • Author(s)
      Yoshimoto T.
    • Organizer
      The 4^<th> Surface Barrier Immunology Study Group, 2^<nd> Meeting
    • Place of Presentation
      Tokyo
    • Year and Date
      2010-01-29
    • Related Report
      2011 Final Research Report
  • [Book] Importance of Th17-and Th1-associated responses for the development of asthma, In : Inflammation and Allergy Drug Design2011

    • Author(s)
      Yoshimoto T. Tsutsui, H, Nakanishi K.(Izuhara, K., Holgate, S. T., Wills-Karp M. eds.)
    • Publisher
      Blackwell Publishing
    • Related Report
      2011 Final Research Report
  • [Book] Importance of Th17- and Th1-associated responses for the development of asthma. In : Inflammation and Allergy Drug Design(Izuhara, K., Holgate, S.T., Wills-Karp M.eds.)2011

    • Author(s)
      Yoshimoto, T.Tsutsui, H., Nakanishi K.
    • Total Pages
      12
    • Publisher
      Blackwell Publishing Ltd, London
    • Related Report
      2011 Annual Research Report
  • [Book] 感染とアレルギー:寄生虫アレルギー.福田健編.総合アレルギー学2010

    • Author(s)
      善本知広
    • Publisher
      東京:南山堂
    • Related Report
      2011 Final Research Report
  • [Book] 感染とアレルギー:寄生虫アレルギー 総合アレルギー学(福田健編)改訂2版2010

    • Author(s)
      善本知広
    • Total Pages
      3
    • Publisher
      南山堂
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] アレルギー性鼻炎モデル動物,アレルギー性鼻炎治療剤のスクリーニング方法およびその利用2011

    • Inventor(s)
      善本知広
    • Industrial Property Rights Holder
      善本知広
    • Filing Date
      2011-09-27
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] Th1型アレルギー疾患治療用組成物2011

    • Inventor(s)
      中西憲司,善本知広
    • Industrial Property Rights Holder
      中西憲司,善本知広
    • Acquisition Date
      2011-01-28
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] Th2型アレルギー性疾患治療薬及び感染症治療薬2011

    • Inventor(s)
      善本知広,中西憲司.善本隆之,水口純一
    • Industrial Property Rights Holder
      善本知広,中西憲司.善本隆之,水口純一
    • Acquisition Date
      2011-09-16
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] アレルギー性鼻炎モデル動物,アレルギー性鼻炎治療剤のスクリーニング方法およびその利用2011

    • Inventor(s)
      善本知広
    • Industrial Property Rights Holder
      兵庫医科大学
    • Filing Date
      2011-09-27
    • Related Report
      2011 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi