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Control of itch by topical application of cholecystokinin and its use for novel therapy

Research Project

Project/Area Number 22659208
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Dermatology
Research InstitutionHamamatsu University School of Medicine

Principal Investigator

TOKURA Yoshiki  浜松医科大学, 医学部, 教授 (00172156)

Co-Investigator(Kenkyū-buntansha) MORI Tomoko  産業医科大学, 医学部, 助教 (80399203)
Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,160,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,600,000 (Direct Cost: ¥1,600,000)
Keywordsコレシストキニン / かゆみ / 神経ペプチド / 肥満細胞 / 角化細胞 / 血管内皮細胞 / サブスタンスP / CCK2R / そう痒治療薬
Research Abstract

Cholecystokinin(CCK) serves as a gastrointestinal hormone and also functions as a neuropeptide in central nervous system(CNS). CCK may be a downregulator in CNS as represented by its anti-opioid properties. The existence of CCK in peripheral nervous system has also been reported. We investigated the suppressive effects of various CCKs on the peripheral pruritus in mice. ICR mice were painted with CCK synthetic peptides on the clipped back and injected intradermally with substance P(SP) on the same site. The frequency of SP-induced scratch was reduced significantly by topical application of sulfated CCK8(CCK8S) and CCK7(CCK7S), but not by non-sulfated CCK8, CCK7 or CCK6. Dermal injection of CCK8S also depressed the scratch frequency, suggesting that dermal cells as well as epidermal keratinocytes are the targets of CCKs. By real-time PCR, mRNA for CCK2R, one of the two types of CCK receptors, was expressed highly in mouse fetal skin-derived mast cells(FSMCs) and moderately ICR mouse keratinocytes. CCK8S decreased in vitro compound 48/80-promoted degranulation of FSMCs with a transient elevation of the intracellular calcium concentration. These findings suggest that CCK exerts an anti-pruritic effect mainly via mast cells, and topical CCK may be clinically useful for pruritic skin disorders.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (246 results)

All 2012 2011 2010 2009 Other

All Journal Article (157 results) (of which Peer Reviewed: 157 results) Presentation (65 results) Book (22 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Alopecia areata triggered or exacerbated by swine flu virus infection2012

    • Author(s)
      Ito T, Tokura Y
    • Journal Title

      J Dermatol

      Volume: (in press) Issue: 10 Pages: 863-864

    • DOI

      10.1111/j.1346-8138.2011.01437.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Connexin 26 (GJB2) mutations in keratitis-ichthyosisdeafness (KID) syndrome presenting with squamous cell carcinoma2012

    • Author(s)
      Sakabe J-I, Yoshiki R, Sugita K, Haruyama S, Sawada Y, Kabashima R, Bito T, Nakamura M, Tokura Y
    • Journal Title

      J Dermatol

      Volume: (in press) Issue: 9 Pages: 814-815

    • DOI

      10.1111/j.1346-8138.2011.01414.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Eruptive milium-like syringoma showing eccrine duct origin of milia2011

    • Author(s)
      Tatsuno K, Yagi H, Tokura Y
    • Journal Title

      J Dermatol

      Volume: (in press) Issue: 10 Pages: 878-879

    • DOI

      10.1111/j.1346-8138.2011.01444.x

    • Year and Date
      2011-12-13
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tuberculosis verrucosa cutis with elevation of circulating Th1 and Th17 cells and their reductions after successful treatment2011

    • Author(s)
      Fukamachi S, Kawakami C, Kabashima R, Sawada Y, Sugita K, Nakamura M, Tokura Y
    • Journal Title

      J Dermatol

      Volume: (in press) Issue: 5 Pages: 507-509

    • DOI

      10.1111/j.1346-8138.2011.01317.x

    • Year and Date
      2011-12-02
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Topical cholecystokinin depresses itch-as sociated scratching behavior in mice2011

    • Author(s)
      Fukamachi S, Mori T, Sakabe J-I, Shirai shi N, Kuroda E, Kobayashi M, Bito T, Kabashima K, Nakamura M, Tokura Y
    • Journal Title

      J I nvest Dermatol

      Volume: 131 Pages: 956-961

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of semaphorin 3A expression by calcium concentration and histamine in human keratinocytes and fib roblasts2011

    • Author(s)
      Fukamachi S, Bito T, Shiraishi N, Koba yashi M, Kabashima K, Nakamura M, T okura Y
    • Journal Title

      J Dermatol Sci

      Volume: 62 Pages: 118-123

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of combined topical treatment of acne vul garis with adapalene and nadifloxacin : A randomized study2011

    • Author(s)
      Kobayashi M, Nakagawa T, Fukamachi K, Nakamura M, Tokura Y
    • Journal Title

      J Dermatol

      Volume: 38 Pages: 1163-1166

    • NAID

      10031147162

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Downmodulatory effects of cetirizine and levocetirizine on cytokine/chemokine production and C D54 expression in keratinocytes2011

    • Author(s)
      Kobayashi M, Tokura Y
    • Journal Title

      J Derm atol

      Volume: 38 Pages: 717-719

    • NAID

      10031147074

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of Peripheral Natural Killer Cells and their Reduction in Drug-induce d Hyper-sensitivity Syndrome2011

    • Author(s)
      Sugita K, Kabashima K, Tokura Y
    • Journal Title

      Acta Der m Venereol

      Volume: 92 Pages: 83-84

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Increased expression of mRNAs for I L-4, IL-17, IL-22 and IL-31 in skin lesi ons of subacute and chronic forms of pr urigo2011

    • Author(s)
      Park K, Mori T, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 21 Pages: 135-136

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inflammatory cytokine expression in the skin lesions of tumour necrosis factor receptor-associated periodic syndrome2011

    • Author(s)
      Ohmori S, Nakamura M, Hino R, Kobayashi M, Tokura Y
    • Journal Title

      Rheumatology

      Volume: 51 Pages: 196-199

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] High-Mobility Group Box 1 Protein(HMGB1) as a N ovel Diagnostic Tool for Toxic Epiderma l Necrolysis and Stevens-Johnson Syndro me2011

    • Author(s)
      Nakajima S, Watanabe H, Tohyama M, Sugita K, Iijima M, Hashimoto K, Tokur a Y, Nishimura Y, Doi H, Tanioka M, Miyachi Y, Kabashima K
    • Journal Title

      Arch Dermatol

      Volume: 147 Pages: 1110-1112

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Epiletic seiz ures and cholinergic urticaria with gener alized hypohidrosis and anhidrosis2011

    • Author(s)
      Sawada Y, Bito T, Kabashia R, Sugita K, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 21 Pages: 99-100

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A c ase of cholinergic urticaria associated wit h acquired generalized hypohidrosis and reduced acetylcholine receptors : cause an d effect?2011

    • Author(s)
      Nakamizo S, Kurosawa M, Sawada Y, T okura Y, Miyachi Y, Kabashima K
    • Journal Title

      Clin Exp Dermatol

      Volume: 36 Pages: 559-560

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Epithelial-mesenchymal transition in the skin2011

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      J Dermatol Sci

      Volume: 61 Pages: 7-13

    • NAID

      10030889466

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The type of skin eruptions is an independent prognostic indicator for adult T-cell leukemia/lymphoma2011

    • Author(s)
      Sawada Y, Hino R, Hama K, Ohmori S, Fueki H, Yamada S, Fukamachi S, Tajiri M, Kumo R, Yoshioka M, Nakashima D, Sugita K, Yoshiki R, Shimauchi T, Mori T, Izu K, Kobayashi M, Nakamura M, Tokura Y
    • Journal Title

      Blood

      Volume: 117 Pages: 3961-3967

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Topical cholecystokinin depresses itch-associated scratching behavior in mice2011

    • Author(s)
      Fukamachi s, Mori T, Sakabe J-I, Shiraishi N, Kuroda E, Kobayashi M, Bito T, Kabashima K, Nakamura M, Tokura Y
    • Journal Title

      J Invest Dermatol

      Volume: 131 Pages: 956-961

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of semaphorin 3A expression by calcium concentration and histamine in human keratinocytes and fibroblasts2011

    • Author(s)
      Fukamachi S, Bito T, Shiraishi N, Kobayashi M, Kabashima K, Nakamura M, Tokura Y
    • Journal Title

      J Dermatol Sci

      Volume: 62 Pages: 118-123

    • NAID

      10030890103

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inhibition of epidermal growth factor receptor and PI3K/Akt signaling suppresses cell proliferation and survival through regulation of Stat3 activation in human cutaneous squamous cell carcinoma2011

    • Author(s)
      Bito T, Sumita N, Ashida M, Budiyanto A, Ueda M, Ichihashi M, Tokura Y, Nishigori C
    • Journal Title

      J Skin Cancer

      Volume: 2011 Pages: 874571-874571

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficacy of combined topical treatment of acne vulgaris with adapalene and nadifloxacin : A randomized study2011

    • Author(s)
      Kobayashi M, Nakagawa T, Fukamachi K, Nakamura M, Tokura Y
    • Journal Title

      J Dermatol

      Volume: 38 Pages: 1163-1166

    • NAID

      10031147162

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High levels of activation-induced cytidine deaminase expression in adult T-cell leukaemia/lymphoma2011

    • Author(s)
      Nakamura M, Sugita K, Sawada Y, Yoshiki R, Hino R, Tokura Y
    • Journal Title

      Br J Dermatol

      Volume: 165 Issue: 2 Pages: 437-439

    • DOI

      10.1111/j.1365-2133.2011.10342.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Elevated expression of activation-induced cytidine deaminase in T and NK cells from patients with chronic active Epstein-Barr virus infection2011

    • Author(s)
      Nakamura M, Iwata S, Kimura H, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 21 Pages: 780-782

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Downmodulatory effects of cetirizine and levocetirizine on cytokine/chemokine production and CD54 expression in keratinocytes2011

    • Author(s)
      Kobayashi M, Tokura Y
    • Journal Title

      J Dermatol

      Volume: 38 Pages: 717-719

    • NAID

      10031147074

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circulating Th17 cell fluctuation in psoriatic patients treated with topical calcipotriol and betamethasone butyrate propionate2011

    • Author(s)
      Hino R, Kabashima R, Kawakami C, Sugita K, Nakamura M, Tokura Y
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 25 Issue: 2 Pages: 242-244

    • DOI

      10.1111/j.1468-3083.2010.03714.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Therapeutic efficacy of mizoribine for discoid lupus erythematosus with normalized frequency of circulating T helper 17 cells2011

    • Author(s)
      Sugita K, Kabashima R, Kawakami C, Nakamura M, Tokura Y
    • Journal Title

      Clin Exp Dermatol

      Volume: 36 Issue: 3 Pages: 315-317

    • DOI

      10.1111/j.1365-2230.2010.03971.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of Peripheral Natural Killer Cells and their Reduction in Drug-induced Hyper-sensitivity Syndrome2011

    • Author(s)
      Sugita K, Kabashima K, Tokura Y
    • Journal Title

      Acta Derm Venereol

      Volume: 92 Pages: 83-84

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Increased expression of mRNAs for IL-4, IL-17, IL-22 and IL-31 in skin lesions of subacute and chronic forms of prurigo2011

    • Author(s)
      Park K, Mori T, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 21 Pages: 135-136

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular Mapping of Lymph Node Metastases by Real-Time RT-PCR in Two Melanoma Patients2011

    • Author(s)
      Abe-Mukumoto S, Mori T, Sakabe JI, Fukamachi S, Nakamura M, Kabashima K, Tokura Y
    • Journal Title

      J Dermatol

      Volume: 38 Issue: 12 Pages: 1202-1205

    • DOI

      10.1111/j.1346-8138.2011.01204.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High-Mobility Group Box 1 Protein (HMGB1) as a Novel Diagnostic Tool for Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome2011

    • Author(s)
      Nakajima S, Watanabe H, Tohyama M, Sugita K, Iijima M, Hashimoto K, Tokura Y, Nishimura Y, Doi H, Tanioka M, Miyachi Y, Kabashima K
    • Journal Title

      Arch Dermatol

      Volume: 147 Pages: 1110-1112

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple milia and comedones as a skin manifestation of systemic amyloidosis2011

    • Author(s)
      Funai N, Machida s, Ito T, Hirakawa s, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 21 Pages: 638-639

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High-dose Intravenous Immunoglobulin Monotherapy for Drug-induced Hypersensitivity Syndrome2011

    • Author(s)
      Kito Y, Ito T, Hashizume H, Tokura Y
    • Journal Title

      Acta Derm Venereol

      Volume: 92 Pages: 100-101

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Raynaud's phenomenon, digital gangrene and hypergammaglobulinemic purpura occurring in a patient with IgG4-related disease2011

    • Author(s)
      Ikawa T, Kasuya A, Hirakawa S, Tokura Y
    • Journal Title

      Br J Dermatol

      Volume: 165 Issue: 6 Pages: 1359-1366

    • DOI

      10.1111/j.1365-2133.2011.10609.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Superficial angiomyxoma on the scrotum of a child2011

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Pediatr Dermatol

      Volume: 28 Issue: 2 Pages: 200-201

    • DOI

      10.1111/j.1525-1470.2011.01389.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Angiolymphoid hyperplasia with eosinophilia on the leg successfully treated with Th2 cytokine inhibitor suplatast tonsilate2011

    • Author(s)
      Bito T, Kabashima R, Sugita K, Tokura Y
    • Journal Title

      J Dermatol

      Volume: 38 Issue: 3 Pages: 300-302

    • DOI

      10.1111/j.1346-8138.2010.00990.x

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cutaneous pseudolymphoma due to benidipine hydrochloride with massive infiltration of eosinophils2011

    • Author(s)
      Fukamachi S, Sugita K, Nakamura M, Tokura Y
    • Journal Title

      J Dermatol

      Volume: 38 Pages: 935-936

    • NAID

      10030728214

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Epiletic seizures and cholinergic urticaria with generalized hypohidrosis and anhidrosis2011

    • Author(s)
      Sawada Y, Bito T, Kabashia R, Sugita K, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 21 Pages: 99-100

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Necrobiosis lipoidica of the scrotum2011

    • Author(s)
      Sawada Y, Mori T, Nakashima D, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 21 Pages: 98-99

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recurrent annular erythema after thymectomy2011

    • Author(s)
      Sawada Y, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 21 Pages: 425-426

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Keloid exacerbation associated with adult T-cell leukemia/lymphoma cell infiltration2011

    • Author(s)
      Sawada Y, Mori T, Yamada S, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 21 Pages: 646-647

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Generalized fixed drug eruption caused by pazufloxacin2011

    • Author(s)
      Sawada Y, Nakamura M, Tokura Y
    • Journal Title

      Acta Derm Venereol

      Volume: 91 Pages: 600-601

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Schwannomatosis presenting with large subcutaneous and retroperitoneal tumours2011

    • Author(s)
      Yoshizawa M, Sugita K, Haruyama S, Yoshiki R, Hino R, Bito T, Nakamura M, Tokura Y
    • Journal Title

      Clin Exp Dermatol

      Volume: 36 Issue: 5 Pages: 555-557

    • DOI

      10.1111/j.1365-2230.2011.04018.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Atypical large bullae caused by herpes simplex in a patient with thymoma2011

    • Author(s)
      Fueki H, Sugita K, Sawada Y, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 21 Pages: 435-436

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acquired poikiloderma associated with primary biliary cirrhosis2011

    • Author(s)
      Fueki H, Sugita K, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 21 Pages: 118-118

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Calcinosis cutis associated with primary Sjogren's syndrome ; strong expression of osteonectin and matrix Gla protein2011

    • Author(s)
      Fueki H, Hino R, Nakamura M, Tokura Y
    • Journal Title

      Rheumatology (Oxford)

      Volume: 50 Pages: 2318-2320

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case of cholinergic urticaria associated with acquired generalized hypohidrosis and reduced acetylcholine receptors : cause and effect?2011

    • Author(s)
      Nakamizo S, Kurosawa M, Sawada Y, Tokura Y, Miyachi Y, Kabashima K
    • Journal Title

      Clin Exp Dermatol

      Volume: 36 Issue: 5 Pages: 559-560

    • DOI

      10.1111/j.1365-2230.2011.04015.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sebaceous carcinoma arising at a chronic candidiasis skin lesion of apatient with keratitis-ichthyosis-deafness (KID) syndrome2011

    • Author(s)
      Kaku Y, Tanizaki H, Tanioka M, Sakabe J, Miyagawa-Hayashino A, Tokura Y, Miyachi Y, Kabashima K
    • Journal Title

      Br J Dermatol

      Volume: 166 Issue: 1 Pages: 222-224

    • DOI

      10.1111/j.1365-2133.2011.10521.x

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chromoblastomycosis Caused by Fonsecaea monophora2011

    • Author(s)
      杉山由華, 鈴木陽子, 菅谷圭子, 戸倉新樹, 矢口貴志, 亀井克彦, 西村和子
    • Journal Title

      Medical Mycology Journal

      Volume: 52 Issue: 3 Pages: 255-260

    • DOI

      10.3314/mmj.52.255

    • NAID

      10029466342

    • ISSN
      2185-6486, 2186-165X
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] アトピー性皮膚炎に対するタクロリムス軟膏の使用経験-全身への外用療法による皮疹とQOLの改善-2011

    • Author(s)
      伊豆邦夫, 森智子, 戸倉新樹
    • Journal Title

      Progress in Medicine

      Volume: 31 Pages: 1573-1577

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 日光角化症とBowen病に対するメタルハライドランプを用いた光線力学両方(PDT)の治療効果の検討2011

    • Author(s)
      尾藤利憲, 大森俊, 吉澤真衣子, 春山護人, 深田雄宇, 川上千佳, 椛島利江子, 椋本祥子, 杉田和成, 吉木竜太郎, 日野亮介, 森智子, 小林美和, 中村元信, 戸倉新樹
    • Journal Title

      西日本皮膚科

      Volume: 73 Pages: 260-265

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circulating Th17 cell fluctuation in psoriatic patients treated with topical calcipotriol and betamethasone butyrate propionate2011

    • Author(s)
      Hino R, Kabashima R, Kawakami C, Sugita K, Nakamura M, Tokura Y
    • Journal Title

      J Eur Acad Dermatol Vnereol

      Volume: 25 Pages: 242-244

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Inducible Nitric Oxide Synthase Downmodulates Contact Hypersensitivity by Suppressing Dendritic Cell Migration and Survival2010

    • Author(s)
      Sugita K, Kabashima K, Yoshiki R, Iken ouchi-Sugita A, Tsutsui M, Nakamura J, Yanagihara N, Tokura Y
    • Journal Title

      J Inves t Dermatol

      Volume: 130 Pages: 464-471

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comparison of skin barrier function and sensory nerve electric current perception threshold between IgE-high extrinsic and IgE-normal intrinsic types of atopic dermatitis2010

    • Author(s)
      Mori T, Ishida K, Mukumoto S, Yamada Y, Imokawa G, Kabashima K, Kobayas hi M, Bito T, Nakamura M, Ogasawara K, Tokura Y
    • Journal Title

      Br J Dermatol

      Volume: 162 Pages: 83-90

    • NAID

      130004546888

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of Wnt signaling in dermal fibroblasts2010

    • Author(s)
      Kabashima K, Sakabe J-I, Yoshiki R, Ta bata Y, Kohno K, Tokura Y
    • Journal Title

      Am J Pathol

      Volume: 176 Pages: 721-732

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Flaky tail mouse denotes human atopic dermatitis in the steady state and by to pical application with Dermatophagoides pteronyssimus extract2010

    • Author(s)
      Moniaga CS, Egawa G, Kawasaki H, Ch ikuma M, Honda T, Tanizaki H, Nakaji ma S, Matsuoka H, Kubo A, Tokura Y, Miyachi Y, Amagai M, Kabashima K
    • Journal Title

      Am J Pathol

      Volume: 176 Pages: 2385-2393

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The mandatory role of IL-10-producing and OX40L-expresssing mature Langerhans cells in local UVB-induced immunosuppression2010

    • Author(s)
      Yoshiki R, Kabashima K, Sakabe J-I, Su gita K, Bito T, Nakamura M, Malissen B, Tokura Y
    • Journal Title

      J Immunol

      Volume: 84 Pages: 5670-5677

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ultraviolet light induces Stat3 acti vation in human keratinocytes and fibrob lasts through reactive oxygen species and DNA damage2010

    • Author(s)
      Bito T, Sumita N, Masaki T, Shirakawa T, Ueda T, Yoshiki R, Tokura Y, Nishig ori C
    • Journal Title

      Exp Dermatol

      Volume: 19 Pages: 654-660

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Activated regulatory Tcells are the major Tcell type emigrating from the skin during a cutaneous immune response in mice2010

    • Author(s)
      Tomura M, Honda T, Tanizaki H, Otsuk a A, Egawa G, Tokura Y, Waldmann H, Hori S, Cyster JG, Watanabe T, Miyach i Y, Kanagawa O, Kabashima K
    • Journal Title

      J Clin Invest

      Volume: 120 Pages: 883-893

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cholinergic urticaria : Studies on the muscarinic cholinergic receptor M3 in the anhidrotic and hypohidrotic skin2010

    • Author(s)
      Sawada Y, Nakamura M, Bito T, Fukam achi S, Kabashima R, Sugita K, Hino R, Tokura Y
    • Journal Title

      J Invest Dermatol

      Volume: 130 Pages: 2683-2686

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FTY720 regulates bone marrow egress of eosinop hils and modulates late phase skin reacti on in mice2010

    • Author(s)
      Sugita K, Kabashima K, Sakabe J-I, Yos hiki R, Tanizaki H, Tokura Y
    • Journal Title

      Am J Pathol

      Volume: 177 Pages: 1881-1887

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Extrinsic and intrinsic types o f atopic dermatitis2010

    • Author(s)
      Tokura Y
    • Journal Title

      J Dermatol Sci

      Volume: 58 Pages: 1-7

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Inducible Nitric Oxide Synthase Downmodulates Contact Hypersensitivity by Suppressing Dendritic Cell Migration and Survival2010

    • Author(s)
      Sugita K, Kabashima K, Yoshiki R, Ikenouchi-Sugita A, Tsutsui M, Nakamum J, Yanagihara N, Tokura Y
    • Journal Title

      J Invest Dermatol

      Volume: 130 Pages: 464-471

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Food-dependent anaphylaxis with serum IgE immunoreactive to dairy products containing high-molecular-weight proteins2010

    • Author(s)
      Abe S, Kabashima K, Moriyama T, Tokura Y
    • Journal Title

      J Dermatol Sci

      Volume: 57 Pages: 137-140

    • NAID

      10027399736

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Leukemic cutaneous T-cell lymphoma manifesting papuloerythroderma with CD3- CD4+ phenotype2010

    • Author(s)
      Shimauchi T, Sugita K, Nakamura M, Tokura Y
    • Journal Title

      Acta Derm Venereol

      Volume: 90 Pages: 68-72

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tumor cell expression of programmed cell death 1 is a prognostic factor for malignant melanoma2010

    • Author(s)
      Hino R, Kabashima K, Kato Y, Yagi H, Nakamura M, Honjo T, Okaza ki T Tokura Y
    • Journal Title

      Cancer

      Volume: 116 Pages: 1757-1766

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of toxicity and Stat3 activation induced by hydrogen peroxide exposure to the skin in healthy individuals2010

    • Author(s)
      IBito T, Izu K, Tokura Y
    • Journal Title

      J Dermatol Sci

      Volume: 58 Pages: 157-159

    • NAID

      10027400961

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Flaky tail mouse denotes human atopic dermatitis in the steady state and by topical application with Dermatophagoides pteronyssimus extract2010

    • Author(s)
      Moniaga CS, Egawa G, Kawasaki H, Chikuma M, Honda T, Tanizaki H, Nakajima S, Matsuoka H, Kubo A, Tokura Y, Miyachi Y, Amagai M, Kabashima K
    • Journal Title

      Am J Pathol

      Volume: 176 Pages: 2385-2393

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of Snaill in the fibrotic dermis of postmenopausal frontal fibrosing alopecia : possible involvement of an epithelial-mesenchymal transition and a review of the Japanese patients2010

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Br J Dermatol

      Volume: 162 Pages: 1152-1154

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ultraviolet light induces Stat3 activation in human keratinocytes and fibroblasts through reactive oxygen species and DNA damage2010

    • Author(s)
      Bito T, Sumita N, Masaki T, Shirakawa T, Ueda T, Yoshiki R, Tokura Y, Nishigori C
    • Journal Title

      Exp Dermatol

      Volume: 19 Pages: 654-660

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice2010

    • Author(s)
      Tomura M, Honda T, Tanizaki H, Otsuka A, Egawa G, Tokura Y, Waldmann H, Hon S, Cyster JG, Watanabe T, Miyachi Y, Kanagawa O, Kabashima K
    • Journal Title

      J Clin Invest

      Volume: 120 Pages: 883-893

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fluctuation of blood and skin plasmacytoid dendritic cells in drug-induced hypers ensitivity syndrome2010

    • Author(s)
      Sugita K, Tohyama M, Watanabe M, Otsuka A, Nakajima S, Iijima M, Hashimoto K, Tokura Y, Miyachi Y, Kabashima K
    • Journal Title

      J Allergy Clin Immunol

      Volume: 126 Pages: 408-410

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FTY720 regulates bone marrow egress of eosinophils and modulates late phase skin reaction in mice2010

    • Author(s)
      Sugita K, Kabashima K, Sakabe J-I, Yoshiki R, Tanizald H, Tokura Y
    • Journal Title

      Am J Pathol

      Volume: 177 Pages: 1881-1887

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Palmar pseudolymphoma associated with herpes simplex infection2010

    • Author(s)
      Fukamachi S, Kimura T, Kobayashi M, Hino R, Nakamura M, Tokura Y
    • Journal Title

      J Cutan Pathol

      Volume: 37 Pages: 808-811

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel missense mutation in the TRPS1 gene in a case of trichorhinophalangeal syndrome type I (TRPS1) with fish-like malodour2010

    • Author(s)
      Nakamura M, Sugita K, Tokura Y
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 24 Pages: 358-359

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Drug eruption induced by IL-6 receptor inhibitor tocilizumab2010

    • Author(s)
      Yoshiki R, Nakamura M, Tokura Y
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 24 Pages: 495-496

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of a Prominent Granulomatous Eruption after Interferon-gamma The rapy in a Patient with Mycosis Fungoides2010

    • Author(s)
      Haruyama S, Sugita K, Kawakami C, Nakamura M, Tokura Y
    • Journal Title

      Acta Derm Venereol

      Volume: 90 Pages: 190-191

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Eruptive generalized granuloma annulare presenting with numerous micropapules2010

    • Author(s)
      Ine K, Kabashima K, Koga C, Kobavashi M, Tokura Y
    • Journal Title

      Int J Dermatol

      Volume: 49 Pages: 104-105

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ectopic extramammary Paget's disease : case report and literature reiew2010

    • Author(s)
      Sawada Y, Bito T, Kabashima R, Yoshiki R, Hino R, Nakamura M, Masanori S, Tokura Y
    • Journal Title

      Acta Derm Venereol

      Volume: 90 Pages: 502-505

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Epidermolysis bullosa acquisita associated with psoriasis2010

    • Author(s)
      Kabashima R, Hino R, Bito T, Kabashima K, Nakamura M, Oyama B, Hashimoto T, Tokura Y
    • Journal Title

      Acta Derm Venereol

      Volume: 90 Pages: 314-316

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Complete remission of metastatic malignant melanoma after surgery in association with development of systemic vitiligo2010

    • Author(s)
      Nishitani N, Bito T, Ikeda T, Tokura Y, Nishigori C
    • Journal Title

      J Dermatol

      Volume: 37 Pages: 770-772

    • NAID

      10027067126

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A novel missense mutation in tumour necrosis factor receptor superfamily 1A (TNFRSF1A) gene found in tumour necrosis factor receptor-associated periodic syndrome (TRAPS) with high serum interleukin (IL)-222010

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 20 Pages: 1508-509

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple pilomatricomas in association with 21-hydroxylase deficiency2010

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Pediatr Dermatol

      Volume: 27 Pages: 417-417

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acta Derm Venereol2010

    • Author(s)
      Tanizaki H, Matsumura Y, Tokura Y, Miyachi Y, Kabashima K
    • Journal Title

      A case of suppurative granuloma induced by insulin injection

      Volume: 90 Pages: 541-542

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Valsartan-induced Drug Eruption Followed by CD30+ Pesudolymphomatous Eruption2010

    • Author(s)
      Sawada Y, Yoshiki R, Kawakami C, Fukamachi S, Sugita K, Nakamura M, Tokura Y
    • Journal Title

      Acta Derm Venereol

      Volume: 90 Pages: 521-522

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] CD8+ CD56+ Mycosis Fungoides with an Indolent Clinical Behaviour : Case Report and Literature Review2010

    • Author(s)
      Sawada Y, Sugita K, Kabashima R, Hino R, Nakamura M, Koga C, Tokura Y
    • Journal Title

      Acta Derm Venereol

      Volume: 90 Pages: 525-526

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of Snaill in the vimentin-expressing squamous cell carcinoma mimic king atypical fibroxanthoma : possible involvement of an epithelial-mesenchymal transition2010

    • Author(s)
      Nakamura M, Sugita K, Tokura Y
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 24 Pages: 1365-1366

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute hepatic failure secondary to extensive hepatic replacement by metastatic a melanotic melanoma : an autopsy case report2010

    • Author(s)
      Fusasaki T, Narita R, Hiura M, Abe S, Tabaru A, Hino R, Matsuyama A, Shimajiri S, Tokura Y, Sasaguri Y, Harada M
    • Journal Title

      Clin J Gastroenterol

      Volume: 3 Pages: 327-331

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case of laryngeal carcinoma in a young adult with dyskeratosis congenita2010

    • Author(s)
      Komune N, Hara T, Tamae A, Izu K, Tokura Y, Joe AK, Masuda M
    • Journal Title

      Int J Clin Oncol

      Volume: 15 Pages: 428-432

    • NAID

      10026601597

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Generalized eruptive xanthoma with prominent deposition of naked chylomicrons : evidence for chylomicrons as the origin of urate-like crystals.2010

    • Author(s)
      Bito T, Kawakami C, Shimajiri S, Tokura Y
    • Journal Title

      J Cutan Pathol

      Volume: 37 Pages: 1161-1163

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chondrodermatitis of the auricle in patients with atopic dermatitis2010

    • Author(s)
      Sawada Y, Nakamura M, Bito T, Haruyama S, Kabashima R, Sugita K, Kobayashi M, Kabashima K, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 20 Pages: 1813-814

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Angiolymphoid hyperplasia with eosinophilia occurring on the penis2010

    • Author(s)
      Ohmori S, Sugita K, Sawada Y, Hino R, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: 20 Pages: 545-546

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Erosive pustular dermatosis of the scalp and leg associated with myasthenia gravis : A possible pathogenetic role for neutrophil-stimulating cytokines and chemokines2010

    • Author(s)
      Sawada Y, Bito T, Kawakami C, Shimauchi T, Nakamura M, Tokura Y
    • Journal Title

      Acta Derma Venereol

      Volume: 90 Pages: 652-653

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Extrinsic and intrinsic types of atopic dermatitis2010

    • Author(s)
      Tokura Y
    • Journal Title

      J Dermatol Sci

      Volume: 58 Pages: 11-7

    • NAID

      10027400148

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Psorisis and other Th17-mediated skin diseases2010

    • Author(s)
      Tokura Y, Mori T, Hino R
    • Journal Title

      J UOEH

      Volume: 32 Pages: 317-328

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] J UOEH2010

    • Author(s)
      Haruyama S, Sugita K, Kawakami C, Nakamura M, Tokura Y
    • Journal Title

      Spinal cord compression presumably due to metastasized cutaneous squamous cell carcinoma to the thoracic spine

      Volume: 32 Pages: 155-159

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High responses of peripheral lymphocytes to mosquito salivary gland extracts in patients with Wells' syndrome2010

    • Author(s)
      Koga C, Sugita K, Kabashima K, Matsuoka H, Nakamura M, Tokura Y
    • Journal Title

      J Am Acad Dermatol

      Volume: 63 Pages: 160-161

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 本邦に必要とされる専属産業医数:事業所・企業統計調査(総務省統計局経済基本構造統計課)から推計2010

    • Author(s)
      一瀬豊日, 中村早人, 戸倉新樹
    • Journal Title

      産業医科大学雑誌

      Volume: 32 Pages: 73-81

    • NAID

      110007588850

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 塩酸オロパタジン内服によるアトピー性皮膚炎患者の血中サブSタンスPとTh17細胞割合への影響2010

    • Author(s)
      椛島利江子, 尾藤利憲, 田尻真貴子, 川上千佳, 深町晶子, 吉木竜太郎, 杉田和成, 日野亮介, 森智子, 小林美和, 中村元信, 戸倉新樹
    • Journal Title

      西日本皮膚科

      Volume: 72 Pages: 159-161

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 月経に関連した外陰部皮膚症状に関するアトピー性皮膚炎患者へのアンケート調査2010

    • Author(s)
      小林美和, 戸倉新樹, 佐藤紀子, 高木豊, 北原隆, 武馬吉則, 河崎宏典
    • Journal Title

      西日本皮膚科

      Volume: 72 Pages: 385-389

    • NAID

      10026637000

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ベシル酸ベポタスチン内服によるアトピー性皮膚炎患者の止痒効果とTh17細胞,Th2細胞の変動2010

    • Author(s)
      椛島利江子, 尾藤利憲, 日野亮介, 中村元信, 戸倉新樹
    • Journal Title

      Progress in Medicine

      Volume: 30 Pages: 2229-2232

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ロキシスロマイシンの皮膚免疫調整作用2010

    • Author(s)
      小林美和, 吉木竜太郎, 坂部純一, 中村元信, 戸倉新樹
    • Journal Title

      皮膚の科学

      Volume: 9 Pages: 17-20

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ミゾリビン内服が有効であった慢性苔癬状枇糠疹2010

    • Author(s)
      杉田和成, 椛島利江子, 中村元信, 戸倉新樹
    • Journal Title

      日本皮膚アレルギー・接触皮膚炎学会雑誌

      Volume: 4 Pages: 47-50

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 発症から40年以上経過した皮膚疣状結核2010

    • Author(s)
      深町晶子, 川上千佳, 戸倉新樹
    • Journal Title

      皮膚病診療

      Volume: 32 Pages: 259-262

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 上腕に商事,懸垂状外観を呈した巨大メルケル細胞癌2010

    • Author(s)
      椛島利江子, 尾藤利憲, 春山護人, 椋本祥子, 吉木竜太郎, 中村元信, 山本修, 戸倉新樹
    • Journal Title

      Skin Cancer

      Volume: 25 Pages: 38-41

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Birt-Hogg-Dube症候群2010

    • Author(s)
      田尻真貴子, 永田貴久, 山下淳二, 三宅大我, 戸倉新樹
    • Journal Title

      西日本皮膚科

      Volume: 72 Pages: 567-568

    • NAID

      130004475375

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 全身に白斑を伴った転移性悪性黒色腫の寛解例2010

    • Author(s)
      西谷奈生, 尾藤利憲, 池田哲也, 戸倉新樹, 錦織千佳子
    • Journal Title

      Skin Cancer

      Volume: 25 Pages: 141-144

    • NAID

      10027731588

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 両上肢対称性に生じた線状強皮症の1例2010

    • Author(s)
      大森峻, 島内隆寿, 中村元信, 戸倉新樹
    • Journal Title

      日小児皮会雑誌

      Volume: 29 Pages: 1155-117

    • NAID

      10027698483

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 薬剤アレルギーにおけるDLST2010

    • Author(s)
      戸倉新樹, 深町晶子, 杉田和成
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 53 Pages: 278-283

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 皮疹の診かたとその記載法2010

    • Author(s)
      戸倉新樹
    • Journal Title

      小児科

      Volume: 51 Pages: 536-541

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 小児アトピー性皮膚炎患者に対するセチリジンの有効性と安全性:文献的考察と一例報告2010

    • Author(s)
      戸倉新樹
    • Journal Title

      アレルギー・免疫

      Volume: 17 Pages: 142-149

    • NAID

      40017113912

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] アトピー性皮膚炎の二大分別を考慮したかゆみ治療の新たな話題2010

    • Author(s)
      戸倉新樹
    • Journal Title

      Medico

      Volume: 41 Pages: 194-198

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 内因性アトピーと外因性アトピー2010

    • Author(s)
      戸倉新樹, 椛島利江子
    • Journal Title

      アレルギーの臨床

      Volume: 401 Pages: 404-409

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ロキシスロマイシンによるケラチノサイトのTh2ケモカイン産生抑制およびTh2細胞のケモカインケモカインレセプターの発現抑制2010

    • Author(s)
      小林美和, 島内隆寿, 日野亮介, 戸倉新樹
    • Journal Title

      皮膚の科学

      Volume: 9 Pages: 1-5

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 乾癬のサイトカイン異常update2010

    • Author(s)
      戸倉新樹
    • Journal Title

      MB Derma

      Volume: 169 Pages: 9-14

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 蚊刺過敏症の背後に隠れるEBウイルス関連NK細胞リンパ増殖性疾患2010

    • Author(s)
      戸倉新樹
    • Journal Title

      皮膚アレルギーフロンティア

      Volume: 8 Pages: 85-89

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] アトピー性皮膚炎:バリア異常とアレルギー.第38回日本アレルギー学会専門医教育セミナー2010

    • Author(s)
      戸倉新樹
    • Journal Title

      日本アレルギー学会編

      Pages: 23-27

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 貴方も名医:肥満細胞症2010

    • Author(s)
      笛木はるな, 戸倉新樹
    • Journal Title

      Clinic Magazine

      Volume: 493

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 薬剤アレルギーにおけるDLST2010

    • Author(s)
      戸倉新樹
    • Journal Title

      マルホ皮膚科セミナー放送内容集

      Volume: 207 Pages: 9-13

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 乾癬・アトピー性皮膚炎と免疫2010

    • Author(s)
      戸倉新樹
    • Journal Title

      日皮会誌

      Volume: 120 Pages: 2175-2180

    • NAID

      130004708705

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 職業性皮膚疾患NAVI2010

    • Author(s)
      戸倉新樹
    • Journal Title

      デルマ倶楽部

      Volume: 9 Pages: 5-6

    • NAID

      10024323288

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] いま,接触皮膚炎は.皮膚アレルギーコンパクトセミナー2010

    • Author(s)
      戸倉新樹, 宮地良樹
    • Volume
      6
    • Pages
      4-7
    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rosa cea-like demodicosis mimicking cutaneou s lymphoma

    • Author(s)
      Kito Y, Hashizume H, Tokura Y
    • Journal Title

      Acta Derm Venereol

      Volume: (in press)

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Haemodialysis-induced pseudoporphyria successfully treated with glutathione

    • Author(s)
      Kasuya A, Hashizume H, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pathogenesis of alopecia areata : why does alopecia areata develop in a round pattern?

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Exp Dermatol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Decreased expression of homeostatic chemokine receptors in intravascular large B-cell lymphoma : A study of three cases

    • Author(s)
      Kasuya A, Fujiyama T, Shirahama S, Hashizume H, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Blocking of CTLA-4 on lymphocytes improves the sensitivity of lymphocyte transformation test in a patient with nickel allergy

    • Author(s)
      Sugita K, Kabashima K, Sawada Y, Haruyama s, Yoshioka M, Mori T, Ogasawara K, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rosacea-like demodicosis mimicking cutaneous lymphoma

    • Author(s)
      Kito Y, Hashizume H, Tokura Y
    • Journal Title

      Acta Derm Venereol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Histiocytoid Sweet's syndrome associated with t(9;22)(q34;q11)-positive chronic myelogenous leukemia : Immature granulocytic origin of histiocytic cells

    • Author(s)
      Kasuya A, Fujiyama T, Hashizume H, Inuzuka M, Tokura Y
    • Journal Title

      Int J Dermatol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute onset disseminated superficial porokeratosis associated with exacerbation of diabetes mellitus due to development of anti-insulin antibodies

    • Author(s)
      Nakamura M, Fukamachi s, Tokura Y
    • Journal Title

      Dermatoendocrinol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Congenital onychodysplasia of the index finger in a child with meconium aspiration syndrome

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Int J Dermatol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Methylmalonic aciduria presenting with recurrent multiple molluscum contagiosum lesions

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Dermatoendocrinol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A high serum concentration of chemerin in pustular dermatitis paradoxically induced by etanercept

    • Author(s)
      Sawada Y, Nakamura M, Hama K, Hino R, Tokura Y
    • Journal Title

      J Am Acad Dermatol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Occupational skin cancer arising in a patient with a high frequency of circulating regulatory T cells

    • Author(s)
      Ohmori S, Mori T, Haruyama S, Sawada Y, Hino R, Nakamura M, Tokura Y
    • Journal Title

      Int J Dermatol

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Increased circulating Th17 frequencies and serum IL-22 levels in patients with acute generalized exanthematous pustulosis

    • Author(s)
      Kabashima R, Sugita K, Sawada Y, Hino R, Nakamura M, Tokura Y
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acute onset disseminated superficial porokeratosis associated with exacerbation of diabetes mellitus due to development of anti-insulin antibodies

    • Author(s)
      Nakamura M, Fukamachi S, Tokura Y
    • Journal Title

      Dermatoendocrinol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Connexin 26 (GJB2) mutations in keratitis-ichthyosis-deafness (KID) syndrome developing squamous cell caricinoma

    • Author(s)
      Sakabe JI, Yoshiki R, Sugita K, Haruyama S, Sawada Y, Kabashima R, Bito T, Nakamura M, Tokura Y
    • Journal Title

      J Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Occupational skin cancer arising in a patient with a high frequency of circulating regulatory T cells

    • Author(s)
      Ohmori S, Mori T, Haruyama S, Sawada Y, Hino R, Nakamura M, To Kura Y
    • Journal Title

      Int J Dermatol

      Volume: (提出済)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Alopecia universalis...

    • Author(s)
      Kabashima R, Nakamura M, Tokura Y
    • Journal Title

      Acta Derma Venereol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Prostanoid receptors as possible targets for anti-allergic drugs : Recent advances in prostanoids on allergy and immunology

    • Author(s)
      Honda T, Tokura Y, Miyachi Y, Kabashima K
    • Journal Title

      Current Drug Targets

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Skin, Drug and Chemical Reactions

    • Author(s)
      Alenius H, Roberts DW, Tokura Y, Lauerma A, Patlewicz, Roberts MS
    • Journal Title

      Drug Discovery Today

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pathogenesis of alopecia areata : why does alopecia areata develop in a round pattern?

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Exp Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of SNAI1 and TWIST1 in the eccrine glands of systemic sclerosis patients : possible involvement of epithelial-mesenchymal transition in the pathogenesis

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Br J Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Congenital onychodysplasia of the index finger in a child with meconium aspirati on syndrome

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Int J Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Systemic cholesterol embolization syndrome in a patient positive for anti-cardiolip in antibody

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Dermatoendocrinol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Methylmalonic aciduria presenting with recurrent multiple molluscum contagiosum lesions

    • Author(s)
      Nakamura M, Tokura Y
    • Journal Title

      Dermatoendocrinol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Epiletic seizures and cholinergic urticaria with generalized hypohidrosis and anhidrosis

    • Author(s)
      Sawada Y, Bito T, Kabashia R, Sugita K, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Necrobiosis lipoidica of the scrotum

    • Author(s)
      Sawada Y, Mori T, Nakashima D, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Acquired poikiloderma associated with primary biliary cirrhosis

    • Author(s)
      Fueki H, Sugita K, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Schwannomatosis presenting with large subcutaneous and retroperitoneal tumours : report of a case and review of the literature

    • Author(s)
      Yoshizawa M, Sugita K, Hariyama S, Yoshiki R, Hino R, Bito T, Nakamura M, Tokura Y:
    • Journal Title

      Clin Exp Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case of cholinergic urticaria associated with acquired generalized hypohidrosis and reduced acetylcholine receptors : cause and effect?

    • Author(s)
      Nakamizo S
    • Journal Title

      Clin Exp Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular Mapping of Lymph Node Metastases by Real-Time RT-PCR in Two Melanoma Patients

    • Author(s)
      Abe-Mukumoto S, Mori T, Sakabe JI, Fukamachi S, Nakamura M, Kabashima K, Tokura Y
    • Journal Title

      J Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Therapeutic efficacy of mizoribine for discoid lupus erythematosus with normalized frequency of circulating T helper 17 cells

    • Author(s)
      Sugita K, Kabashima R, Kawakami C, Nakamura M, Tokura Y
    • Journal Title

      Clin Exp Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Topical Cholecystokinin Depresses Itch-Associated Scratching Behavior in Mice

    • Author(s)
      Fukamachi S, Mori T, Sakabe J-I, Shiraishi N, Kuroda E, Kobayashi M, Bito T, Kabashima K, Nakamura M, Tokura Y
    • Journal Title

      J Invest Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The type of skin eruptions is an independent prognostic indicator for adult T-cell leukemia/lymphoma

    • Author(s)
      Sawada Y, Hino R, Hama K, Ohmori S, Fueki H, Yamada S, Fukamachi S, Tajiri M, Kumo R, Yoshioka M, Nakashima D, Sugita K, Yoshiki R, Shimauchi T, Mori T, Izu K, Kobayashi M, Nakamura M, Tokura Y
    • Journal Title

      Blood

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Increased expression of mRNAs for IL-4, IL-17, IL-22 and IL-31 in skin lesions of subacute and chronic forms of prurigo

    • Author(s)
      Park K, Mori M, Nakamura M, Tokura Y
    • Journal Title

      Eur J Dermatol

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Downmodulatory effects of cetirizine and levocetirizine on cytokine/chemokine production and CD54 expression in keratinocytes

    • Author(s)
      Kobayashi M, Tokura Y
    • Journal Title

      J Dermatol

      Volume: (印刷中)

    • NAID

      10031147074

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 紫外線による皮膚免疫能の抑制

    • Author(s)
      戸倉新樹
    • Journal Title

      日皮会誌

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 化学熱傷

    • Author(s)
      戸倉新樹
    • Volume
      (印刷中)
    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Skin barrier impairment is het erogeneous in atopic dermatitis2011

    • Author(s)
      Tokura Y
    • Organizer
      The 36th Annual Meeting of the Japanese Socie ty for Investigative Dermatology
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2011-12-10
    • Related Report
      2011 Final Research Report
  • [Presentation] Skin barrier impairment is heterogeneous in atopic dermatitis2011

    • Author(s)
      Tokura Y
    • Organizer
      The 36th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Kyoto, Japan(招待講演)
    • Year and Date
      2011-12-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] Atopic dermatitis and skin ba rrier in the extrinsic and intrinsic types2011

    • Author(s)
      Tokura Y
    • Organizer
      The 37^<th> Annual Meeting of the Taiwane se Dermatological Association
    • Place of Presentation
      Taipei, Taiwan.
    • Year and Date
      2011-11-26
    • Related Report
      2011 Final Research Report
  • [Presentation] Atopic dermatitis and skin barrier in the extrinsic and intrinsic types2011

    • Author(s)
      Tokura Y
    • Organizer
      The 37^<th> Annual Meeting of the Taiwanese Dermatological Association
    • Place of Presentation
      Taipei, Taiwan(招待講演)
    • Year and Date
      2011-11-26
    • Related Report
      2011 Annual Research Report
  • [Presentation] 内因性アトピー性皮膚炎2011

    • Author(s)
      戸倉新樹
    • Organizer
      第62回日本皮膚科学会中部支部学術大会
    • Place of Presentation
      四日市
    • Year and Date
      2011-11-20
    • Related Report
      2011 Final Research Report
  • [Presentation] 内因性アトピー性皮膚炎2011

    • Author(s)
      戸倉新樹
    • Organizer
      第62回日本皮膚科学会中部支部学術大会
    • Place of Presentation
      四日市(招待講演)
    • Year and Date
      2011-11-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] 外来性物質に対する皮膚アレルギー反応機構2011

    • Author(s)
      戸倉新樹
    • Organizer
      第61回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京都
    • Year and Date
      2011-11-11
    • Related Report
      2011 Final Research Report
  • [Presentation] 外来性物質に対する皮膚アレルギー反応機構2011

    • Author(s)
      戸倉新樹
    • Organizer
      第61回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京都(招待講演)
    • Year and Date
      2011-11-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] 薬剤アレルギーにおけるT細胞,NK細胞,樹状細胞の変動2011

    • Author(s)
      杉田和成, 椛島健治, 中村元信, 戸倉新樹
    • Organizer
      第61回日本アレルギー学会秋季学術大会
    • Place of Presentation
      東京都(招待講演)
    • Year and Date
      2011-11-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] 紫外線による免疫抑制を考える2011

    • Author(s)
      戸倉新樹
    • Organizer
      日本皮膚科学会愛媛地方会佐山浩二教授就任記念第54回学術大会
    • Place of Presentation
      松山市(招待講演)
    • Year and Date
      2011-09-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Adult T-cell leukemia/lymphoma : Tree neoplasm with affinity to the skin2011

    • Author(s)
      Tokura Y
    • Organizer
      International Immunodermatology Symposium (Post-ESDR 2011)
    • Place of Presentation
      Heidelberg, Germany(招待講演)
    • Year and Date
      2011-09-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] 成人T細胞性白血病/リンパ腫の皮疹型と予後の解析2011

    • Author(s)
      戸倉新樹, 澤田雄宇
    • Organizer
      第27回日本皮膚悪性腫瘍学会学術大会
    • Place of Presentation
      東京都(招待講演)
    • Year and Date
      2011-06-04
    • Related Report
      2011 Annual Research Report
  • [Presentation] Adult T-cell leukemia/lymphoma and HTLV-1. Cutaneous Lymphomas of Viral Origin2011

    • Author(s)
      Tokura Y
    • Organizer
      22^<nd> World Congress of Dermatology
    • Place of Presentation
      Seoul, Korea(招待講演)
    • Year and Date
      2011-05-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Immunosuppression and Complications in the Disordered Axis of TNF-α and Th17 Cells2011

    • Author(s)
      Tokura Y
    • Organizer
      22^<nd> World Congress of Dermatology
    • Place of Presentation
      Seoul, Korea(招待講演)
    • Year and Date
      2011-05-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Extrinsic and intrinsic types o f atopic dermatitis. Ancillary Meeting on Atopic Dermatitis2011

    • Author(s)
      Tokura Y
    • Organizer
      22^<nd> World Congress of Dermatology
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-05-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Recent concept on the role of cutaneous dendritic cells in UVB-induce d immunosuppression2011

    • Author(s)
      Tokura Y
    • Organizer
      22^<nd> World Congress of Dermatology 2011
    • Place of Presentation
      Seo ul, Korea
    • Year and Date
      2011-05-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Extrinsic and intrinsic types of atopic dermatitis. Ancillary Meeting on Atopic Dermatitis2011

    • Author(s)
      Tokura Y
    • Organizer
      22^<nd> World Congress of Dermatology 2011
    • Place of Presentation
      Seoul, Korea(招待講演)
    • Year and Date
      2011-05-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Recent concept on the role of cutaneous dendritic cells in UVB-induced immunosuppression2011

    • Author(s)
      Tokura Y
    • Organizer
      22^<nd> World Congress of Dermatology 2011
    • Place of Presentation
      Seoul, Korea(招待講演)
    • Year and Date
      2011-05-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] Photoimmunology : sensitization and suppression2011

    • Author(s)
      Tokura Y
    • Organizer
      Australasian Society for Dermatology Research 2011 Annual Scientific Meeting
    • Place of Presentation
      Perth, Australia(招待講演)
    • Year and Date
      2011-05-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新しい抗ヒスタミン薬とその特徴2011

    • Author(s)
      戸倉新樹
    • Organizer
      第74回日本皮膚科学会東京支部学術大会
    • Place of Presentation
      ホテルグランパシフィックLEDAIBA(東京都)
    • Year and Date
      2011-02-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] 外因性.内因性という分別はアトピー性皮膚炎に必要か2011

    • Author(s)
      戸倉新樹
    • Organizer
      第16回アトピー性皮膚炎治療研究会シンポジウム
    • Place of Presentation
      小倉市
    • Year and Date
      2011-02-05
    • Related Report
      2011 Final Research Report
  • [Presentation] 外因性・内因性という分別はアトピー性皮膚炎に必要か2011

    • Author(s)
      戸倉新樹
    • Organizer
      第16回アトピー性皮膚炎治療研究会シンポジウム
    • Place of Presentation
      小倉市(招待講演)
    • Year and Date
      2011-02-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] 外因性・内因性という分別はアトピー性皮膚炎に必要か2011

    • Author(s)
      戸倉新樹
    • Organizer
      第16回アトピー性皮膚炎治療研究会シンポジウム
    • Place of Presentation
      北九州国際会議場(北九州市)
    • Year and Date
      2011-02-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] The type of skin eruptions is an independent prognostic indicator for adult T cell leukemia/lymphoma (ATLL)2011

    • Author(s)
      Tokura Y
    • Organizer
      5^<th> International Symposium on the Biology and Immunology of Cutaneous Lymphomas
    • Place of Presentation
      Berlin, Germany(招待講演)
    • Year and Date
      2011-01-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] The type of skin eruptions is an independent prognostic indicator for adult T cell leukemia/lymphoma(ATLL).2011

    • Author(s)
      Tokura Y
    • Organizer
      The 5^<th> International Symposium on the Biology and Immunology of Cutaneous Lymphomas
    • Place of Presentation
      Kaiserin-Friedrich-Haus, Berlin
    • Year and Date
      2011-01-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] Th17細胞と皮膚疾患2011

    • Author(s)
      戸倉新樹
    • Organizer
      第39回日本臨床免疫学会総会
    • Place of Presentation
      東京都
    • Related Report
      2011 Final Research Report
  • [Presentation] Th17細胞と皮膚疾患2011

    • Author(s)
      戸倉新樹
    • Organizer
      第39回日本臨床免疫学会総会
    • Place of Presentation
      東京都(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] Extrinsic and intrinsic types of atopic dermatitis2010

    • Author(s)
      Tokura Y
    • Organizer
      The 35^<th> Annual Mee ting of Japanese Society for Investigative Dermatology
    • Place of Presentation
      Wakayama Prefectural Cultural Hall, Wakayama
    • Year and Date
      2010-12-04
    • Related Report
      2011 Final Research Report
  • [Presentation] Extrinsic and intrinsic types of atopic dermatitis2010

    • Author(s)
      Tokura Y
    • Organizer
      The 35^<th> Annual Meeting of Japanese Society for Invest igative Dermatology
    • Place of Presentation
      Wakayama Prefectural Cultural Hall, Wakayama
    • Year and Date
      2010-12-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] 女性医師を痛めないために2010

    • Author(s)
      戸倉新樹
    • Organizer
      皮膚科の女性医師を考える会:東部支部企画
    • Place of Presentation
      江陽グランドホテル(仙台市)
    • Year and Date
      2010-11-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] 抗ヒスタミン薬の新しい展開2010

    • Author(s)
      戸倉新樹
    • Organizer
      第74回日本皮膚科学会東部支部学術大会
    • Place of Presentation
      江陽グランドホテル(仙台市)
    • Year and Date
      2010-11-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] 二つのアトピー性皮膚炎:外因性と内因性2010

    • Author(s)
      戸倉新樹
    • Organizer
      日本香粧品学会第35回教育セミナー
    • Place of Presentation
      ヤクルトホール(東京都)
    • Year and Date
      2010-11-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] ベポタスチンベシル酸塩の皮膚炎抑制機序:角化細胞からTh17細胞まで亘る新観点2010

    • Author(s)
      戸倉新樹
    • Organizer
      第62回日本皮膚科学会西部支部学術大会
    • Place of Presentation
      倉敷市芸文館(倉敷市)
    • Year and Date
      2010-10-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] アトピー性皮膚炎:バリア異常とアレルギー2010

    • Author(s)
      戸倉新樹
    • Organizer
      第38回日本アレルギー学会専門医教育セミナー
    • Place of Presentation
      総評会館(東京都)
    • Year and Date
      2010-08-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 抗ヒスタミン薬の今日的話題を問う2010

    • Author(s)
      戸倉新樹
    • Organizer
      第34回日本小児皮膚科学会
    • Place of Presentation
      ひめぎんホール(松山市)
    • Year and Date
      2010-07-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] 皮膚疾患とケモカイン2010

    • Author(s)
      戸倉新樹
    • Organizer
      第75回日本インターフェロン・サイトカイン学会
    • Place of Presentation
      北九州国際会議場(北九州市)
    • Year and Date
      2010-06-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] やさしいリンフォーマ2010

    • Author(s)
      戸倉新樹
    • Organizer
      第26回日本皮膚悪性腫瘍学会学術大会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2010-06-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] ざ瘡治療ガイドラインに沿った最適な治療とは?2010

    • Author(s)
      戸倉新樹
    • Organizer
      第26回に本臨床皮膚科医会総会・学術大会
    • Place of Presentation
      ホテルグランパシフィックLEDAIBA(東京都)
    • Year and Date
      2010-05-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] Psoriasis and Th17-mediated skin diseases2010

    • Author(s)
      Tokura Y
    • Organizer
      Shanghai Immunodermatology Forum
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2010-05-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Association of autologous sweat allergy and metal allergy with the intrinsic type of atopic dermatitis2010

    • Author(s)
      Bito T, Kabashima R, Fukamachi S, Yoshiki R, Hino R, Mori T, Nichigon C, Tokura Y
    • Organizer
      The 70^<th> Annual Meeting of Society for Investigative Dermatology
    • Place of Presentation
      Hilton Atlanta Hotel, Atlanta, Georgia?
    • Related Report
      2010 Annual Research Report
  • [Presentation] The intrinsic type of atopic dermatitis shows normal barrier function, lack of filaggrin mutations, high percentage of Thl cells, and high frequency of metal allergy2010

    • Author(s)
      Kabashima R, Nakamura M, Kobayashi M, Bito T, Kabashima K, Nomura Y, Akiyama M, Shimizu H, Tokura Y
    • Organizer
      The 70^<th> Annual Meeting of Society for Investigative Dermatology
    • Place of Presentation
      Hilton Atlanta Hotel, Atlanta, Georgia?
    • Related Report
      2010 Annual Research Report
  • [Presentation] Classification of skin manifestations of adult T-cell leukemia/lymphoma useful for staging and predictive for prognosis2010

    • Author(s)
      Sawada Y, Hino R, Hama K, Nakamura M, Tokura Y
    • Organizer
      The 70^<th> Annual Meeting of Society for Investigative Dermatology
    • Place of Presentation
      Hilton Atlanta Hotel, Atlanta, Georgia?
    • Related Report
      2010 Annual Research Report
  • [Presentation] Diagnostic detection of micrometastasis to sentinel lymph nodes by real-time PCR analysis in malignant melanoma2010

    • Author(s)
      Mukumoto S, Hino R, Mori T, Sakabe J, Nakamura M, Tokura Y
    • Organizer
      The 70^<th> Annual Meeting of Society for Investigative Dermatology
    • Place of Presentation
      Hilton Atlanta Hotel, Atlanta, Georgia?
    • Related Report
      2010 Annual Research Report
  • [Presentation] Increased expression of activation-induced cytidine deaminase in chronic active Epstein-Barr virus infection leads to neoplastic development2010

    • Author(s)
      Nakamura M, Kimura H, Tokura Y
    • Organizer
      The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Wakayama Prefectural Cultural Hall, Wakayama?
    • Related Report
      2010 Annual Research Report
  • [Presentation] Epithelial-mesenchymal transition in skin fibrosis and tumor formation2010

    • Author(s)
      Nakamura M, Tokura Y
    • Organizer
      The 40^<th> European Society of Dermatology Research Annual Meeting
    • Place of Presentation
      Scandic Marina Congress Center, Helsinki, Finland
    • Related Report
      2010 Annual Research Report
  • [Presentation] Controlled delivery of T-box21 (T-bet) small interfering RNA (siRNA) using cationized gelatin ameliorates autoimmune alopecia (alopecia areata) in a C3H/FleJ mouse model2010

    • Author(s)
      Nakamura M, Tabata Y, Tokura Y
    • Organizer
      The 14^<th> International Congress of Immunology
    • Place of Presentation
      Kobe Convention Center Complex
    • Related Report
      2010 Annual Research Report
  • [Presentation] New approach for a hair follicle regeneration using mouse induced pluripotent stem cells2010

    • Author(s)
      Nakamura M, Tokura Y
    • Organizer
      The 6^<th> World Congress of Hair Research
    • Place of Presentation
      Cairns Convention Centre, Cairns, Australia?
    • Related Report
      2010 Annual Research Report
  • [Presentation] Spicular form titanium dioxide induces IL-1 alpha/beta production of keratinocytes2010

    • Author(s)
      Kobayashi M, Sakabe J, Nakamura M, Tokura Y
    • Organizer
      The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Wakayama Prefectural Cultural Hall, Wakayama?
    • Related Report
      2010 Annual Research Report
  • [Presentation] Inhibition of immediate and late-phase cutaneous reactions by blockade of D1-like dopamine receptors2010

    • Author(s)
      Mori T, Kabashima K, Kuroda E, Sakabe J, Fukamachi S, Kobayashi M, Nakajima S, Nakano K, Tanaka Y, Yamashita S, Tokura Y
    • Organizer
      The 14th International Congress of immunology
    • Place of Presentation
      Kobe Convention Center Complex?
    • Related Report
      2010 Annual Research Report
  • [Presentation] Increased expression of mRNAs for IL-4, IL-17, IL-22 and IL-31 in skin lesions of subacute and chronic forms of prurigo2010

    • Author(s)
      Mori T, Park K, Nakamura M, Tokura Y
    • Organizer
      The First Eastern Asia Dermatology Congress
    • Place of Presentation
      Hotel New Otani Hakata, Fukuoka
    • Related Report
      2010 Annual Research Report
  • [Presentation] Inhibition of immediate and late-phase cutaneous reactions by blockade of D1-like dopamine receptors2010

    • Author(s)
      Mori T, Kabashima K, Sakabe JI, Kuroda E, Fukamachi S, Kobayashi M, Nakajima S, Nakamura M, Tokura Y
    • Organizer
      The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Wakayama Prefectural Cultural Hall, Wakayama
    • Related Report
      2010 Annual Research Report
  • [Presentation] Local UVB-induced immunosuppression is mediated by IL-10 producing and OX40L-positive mature Langerhans cells.2010

    • Author(s)
      Yoshiki R, Kabashima K, Sakabe J, Sugita K, Bito T, Nakamura M, Tokura Y
    • Organizer
      The 14th International Congress of Immunology
    • Place of Presentation
      Kobe Convention Center Conplex, Kobe?
    • Related Report
      2010 Annual Research Report
  • [Presentation] A novel role of the distribution of plasmacytoid dendritic cells for HHV-6 reactivation in drug-induced hypersensitivity syndrome2010

    • Author(s)
      Sugita K, Tohyama M, Watanabe H, Iijima M, Hashimoto K, Miyachi Y, Tokura Y, Kabashima K
    • Organizer
      The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Wakayama Prefectural Cultural Hall, Wakayama
    • Related Report
      2010 Annual Research Report
  • [Presentation] Barrier function-based immunological differences between extrinsic and intrinsic types of atopic dermatitis2010

    • Author(s)
      Kabashima R, Nakamura M, Sakabe J, Fukamachi S, Sugita K, Hino R, Mori T, Kobayashi M, Bito T, Kabashima K, Nomura Y, Akiyama M, Shimizu H, Tokura Y
    • Organizer
      The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Wakayama Prefectural Cultural Hall, Wakayama?
    • Related Report
      2010 Annual Research Report
  • [Presentation] Classification of skin manifestations of adult T-cell leukemia/lymphoma (ATLL) useful for staging and predictive for prognosis2010

    • Author(s)
      Sawada Y, Hino R, Hama K, Nakamura M, Tokura Y.
    • Organizer
      Society for Investigative Dermatology
    • Place of Presentation
      Atlanta
    • Related Report
      2010 Annual Research Report
  • [Presentation] Classification of skin manifestations of adult T-cell leukemia/lymphoma (ATLL) useful for staging and predictive for prognosis2010

    • Author(s)
      Sawada Y, Hino R, Hama K, Nakamura M, Tokura Y.
    • Organizer
      American Dermato-Epidemiology Network Annual meeting
    • Place of Presentation
      Atlanta
    • Related Report
      2010 Annual Research Report
  • [Presentation] Classification of skin manifestations of adult T-cell leukemia/lymphoma (ATLL) useful for staging and predictive for prognosis2010

    • Author(s)
      Sawada Y, Hino R, Hama K, Nakamura M, Tokura Y.
    • Organizer
      The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Wakayama Prefectural Cultural Hall, Wakayama
    • Related Report
      2010 Annual Research Report
  • [Presentation] Heparin serves as a natural stimulant of inflammasome and exacerbates the symptoms of TRAPS.2010

    • Author(s)
      Ohmori S, Hino R, Nakamura M, Tokura Y
    • Organizer
      The 40th Annual Meeting of the European Society for Dermatoloeical Research
    • Place of Presentation
      Scandic Marina Congress Center, Helsinki?
    • Related Report
      2010 Annual Research Report
  • [Presentation] Angiolymphoid hyperplasia with eosinophilia occurring on the penis : case report and literature review.2010

    • Author(s)
      Ohmori S, Sugita K, Sawada Y, Hino R, Nakamura M, Tokura Y
    • Organizer
      The First Eastern Asia Dermatology Congress
    • Place of Presentation
      Hotel New Otani Hakata, Fukuoka
    • Related Report
      2010 Annual Research Report
  • [Presentation] Study on heparin as a natural stimulant of inflammasome.2010

    • Author(s)
      Ohmori S, Hino R, Nakamura M, Tokura Y
    • Organizer
      The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Wakayama Prefectural Cultural Hall, Wakayama
    • Related Report
      2010 Annual Research Report
  • [Presentation] PI3-kinase pathway regulates antigen-induced type2 cytokine production from basophils.2010

    • Author(s)
      Sakabe J, Kuroda E, Tokura Y
    • Organizer
      The 14th International Congress of Immunology
    • Place of Presentation
      Kobe Convention Center Conplex, Kobe
    • Related Report
      2010 Annual Research Report
  • [Presentation] The mandatory role of PI3-kinase pathway in IL-4 and IL-13 production by basophils stimulated with IgE and antigen.2010

    • Author(s)
      Sakabe J, Kuroda E, Nakamura M, Tokura Y
    • Organizer
      The 40th European Society of Dermatological Research (ESDR) Meeting
    • Place of Presentation
      Scandic Marina Congress Center, Helsinki
    • Related Report
      2010 Annual Research Report
  • [Presentation] The role of basophil-derived Th2 cytokines in super late phase reaction in vivo2010

    • Author(s)
      Sakabe J, Kuroda E, Nakamura M, Tokura Y
    • Organizer
      The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Wakayama Prefectural Cultural Hall, Wakayama
    • Related Report
      2010 Annual Research Report
  • [Presentation] Association of autologous sweat allergy and metal allergy with the intrinsic type of atopic dermatitis2010

    • Author(s)
      Bito T, Kabashima R, Fukamachi S, Yoshiki R, Hino R, Mori T, Nishigon C, Tokura Y
    • Organizer
      SID 70^<th> Annual Meeting
    • Place of Presentation
      Atlanta Hilton, Atlanta
    • Related Report
      2010 Annual Research Report
  • [Presentation] Analysis of autologous sweat in atopic, dermatitis patients with sweat allergy and/or metal allergy2010

    • Author(s)
      Bito T, Kabashima R, Hino R, Mori T, Horikawa T, Hirasawa N, Tokura Y, Nishigori C
    • Organizer
      The First Eastern Asia Dermatology Congress (EADC)
    • Place of Presentation
      Hotel New Otani Hakata, Fukuoka
    • Related Report
      2010 Annual Research Report
  • [Book] Hypersensitivity to mosquito bites and EBV2011

    • Author(s)
      Tokura Y
    • Publisher
      MEDRANG
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Book] 皮膚科臨床アセット1.アトピー性皮膚炎2011

    • Author(s)
      戸倉新樹
    • Publisher
      中山書店
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Book] 皮膚疾患最新の治療2011-20122011

    • Author(s)
      戸倉新樹
    • Total Pages
      117
    • Publisher
      南江堂
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Book] 皮膚科診療カラーアトラス大系2011

    • Author(s)
      戸倉新樹
    • Publisher
      講談社
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Book] 臨床医必携-全身とかゆみ2011

    • Author(s)
      戸倉新樹
    • Publisher
      診断と治療社
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Book] 高齢者の皮膚トラブルFAQ2011

    • Author(s)
      戸倉新樹
    • Total Pages
      2
    • Publisher
      診断と治療社
    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
  • [Book] 皮膚科臨床アセット2.薬疹診療のフロントライン2011

    • Author(s)
      戸倉新樹
    • Total Pages
      6
    • Publisher
      中山書店
    • Related Report
      2011 Annual Research Report
  • [Book] 皮膚悪性腫瘍取扱い規約第2版2011

    • Author(s)
      戸倉新樹
    • Total Pages
      6
    • Publisher
      金原出版
    • Related Report
      2011 Annual Research Report
  • [Book] 治療薬ハンドブック20112011

    • Author(s)
      織茂弘志, 戸倉新樹
    • Publisher
      じほう
    • Related Report
      2010 Annual Research Report
  • [Book] 皮膚科臨床アセット.1.アトピー性皮膚炎2011

    • Author(s)
      戸倉新樹
    • Publisher
      中山書店
    • Related Report
      2010 Annual Research Report
  • [Book] 皮膚科サブスペシャリティーシリーズ,1冊でわかる皮膚がん2011

    • Author(s)
      島内隆寿, 戸倉新樹
    • Publisher
      文光堂
    • Related Report
      2010 Annual Research Report
  • [Book] 治療薬ハンドブック20102010

    • Author(s)
      織茂弘志, 戸倉新樹(分担執筆)高久史麿(監修)
    • Publisher
      じほう
    • Related Report
      2010 Annual Research Report
  • [Book] ガイドライン外来診療20102010

    • Author(s)
      戸倉新樹(分担執筆)
    • Publisher
      日経メディカル開発
    • Related Report
      2010 Annual Research Report
  • [Book] 看護大辞典第2版2010

    • Author(s)
      戸倉新樹(分担執筆)
    • Total Pages
      7
    • Publisher
      医学書院
    • Related Report
      2010 Annual Research Report
  • [Book] 今日の治療指針第6版2010

    • Author(s)
      戸倉新樹(分担執筆)
    • Publisher
      医学書院
    • Related Report
      2010 Annual Research Report
  • [Book] 標準皮膚科学第9版2010

    • Author(s)
      戸倉新樹(分担執筆)
    • Publisher
      医学書院
    • Related Report
      2010 Annual Research Report
  • [Book] WHAT'S NEW in皮膚科学2010-20112010

    • Author(s)
      礒田英華, 戸倉新樹(分担執筆)
    • Publisher
      メディカルレビュー社
    • Related Report
      2010 Annual Research Report
  • [Book] 小児科臨床ピクシス172010

    • Author(s)
      戸倉新樹(分担執筆)
    • Publisher
      中山書店
    • Related Report
      2010 Annual Research Report
  • [Book] ファーストステップ皮膚免疫学2010

    • Author(s)
      戸倉新樹
    • Publisher
      中外医学社
    • Related Report
      2010 Annual Research Report
  • [Book] 皮膚悪性腫瘍取扱い規約第2版2010

    • Author(s)
      戸倉新樹
    • Publisher
      金原出版
    • Related Report
      2010 Annual Research Report
  • [Book] からだと光の事典2010

    • Author(s)
      戸倉新樹
    • Publisher
      朝倉書店
    • Related Report
      2010 Annual Research Report
  • [Book] Hypersensitivity to mosquito bites and EBV

    • Author(s)
      Tokura Y
    • Publisher
      22^<nd> World Congress of Dermatology Special Book(印刷中)
    • Related Report
      2010 Annual Research Report
  • [Patent(Industrial Property Rights)] 皮膚疾患治療薬2009

    • Inventor(s)
      戸倉新樹・深町晶子
    • Industrial Property Rights Holder
      産業医科大学・浜松医科大学
    • Filing Date
      2009-10-23
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] 皮膚疾患治療薬2009

    • Inventor(s)
      戸倉新樹
    • Industrial Property Rights Holder
      産業医科大学、戸倉新樹
    • Industrial Property Number
      2009-244528
    • Filing Date
      2009-10-23
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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