Control of itch by topical application of cholecystokinin and its use for novel therapy

• Project/Area Number: 22659208
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Single-year Grants
• Research Field: Dermatology
• Research Institution: Hamamatsu University School of Medicine
• Principal Investigator: TOKURA Yoshiki 浜松医科大学, 医学部, 教授 (00172156)
• Co-Investigator(Kenkyū-buntansha): MORI Tomoko 産業医科大学, 医学部, 助教 (80399203)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥3,160,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥360,000); Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2010: ¥1,600,000 (Direct Cost: ¥1,600,000)
• Keywords: コレシストキニン / かゆみ / 神経ペプチド / 肥満細胞 / 角化細胞 / 血管内皮細胞 / サブスタンスP / CCK2R / そう痒治療薬

Research Abstract

Cholecystokinin(CCK) serves as a gastrointestinal hormone and also functions as a neuropeptide in central nervous system(CNS). CCK may be a downregulator in CNS as represented by its anti-opioid properties. The existence of CCK in peripheral nervous system has also been reported. We investigated the suppressive effects of various CCKs on the peripheral pruritus in mice. ICR mice were painted with CCK synthetic peptides on the clipped back and injected intradermally with substance P(SP) on the same site. The frequency of SP-induced scratch was reduced significantly by topical application of sulfated CCK8(CCK8S) and CCK7(CCK7S), but not by non-sulfated CCK8, CCK7 or CCK6. Dermal injection of CCK8S also depressed the scratch frequency, suggesting that dermal cells as well as epidermal keratinocytes are the targets of CCKs. By real-time PCR, mRNA for CCK2R, one of the two types of CCK receptors, was expressed highly in mouse fetal skin-derived mast cells(FSMCs) and moderately ICR mouse keratinocytes. CCK8S decreased in vitro compound 48/80-promoted degranulation of FSMCs with a transient elevation of the intracellular calcium concentration. These findings suggest that CCK exerts an anti-pruritic effect mainly via mast cells, and topical CCK may be clinically useful for pruritic skin disorders.

Research Products

• [Journal Article] Alopecia areata triggered or exacerbated by swine flu virus infection (2012)
  • Author(s): Ito T, Tokura Y
  • Journal Title: J Dermatol Volume: (in press) Issue: 10 Pages: 863-864
  • DOI: 10.1111/j.1346-8138.2011.01437.x
  • Peer Reviewed
• [Journal Article] Connexin 26 (GJB2) mutations in keratitis-ichthyosisdeafness (KID) syndrome presenting with squamous cell carcinoma (2012)
  • Author(s): Sakabe J-I, Yoshiki R, Sugita K, Haruyama S, Sawada Y, Kabashima R, Bito T, Nakamura M, Tokura Y
  • Journal Title: J Dermatol Volume: (in press) Issue: 9 Pages: 814-815
  • DOI: 10.1111/j.1346-8138.2011.01414.x
  • Peer Reviewed
• [Journal Article] Eruptive milium-like syringoma showing eccrine duct origin of milia (2011)
  • Author(s): Tatsuno K, Yagi H, Tokura Y
  • Journal Title: J Dermatol Volume: (in press) Issue: 10 Pages: 878-879
  • DOI: 10.1111/j.1346-8138.2011.01444.x
  • Year and Date: 2011-12-13
  • Peer Reviewed
• [Journal Article] Tuberculosis verrucosa cutis with elevation of circulating Th1 and Th17 cells and their reductions after successful treatment (2011)
  • Author(s): Fukamachi S, Kawakami C, Kabashima R, Sawada Y, Sugita K, Nakamura M, Tokura Y
  • Journal Title: J Dermatol Volume: (in press) Issue: 5 Pages: 507-509
  • DOI: 10.1111/j.1346-8138.2011.01317.x
  • Year and Date: 2011-12-02
  • Peer Reviewed
• [Journal Article] Topical cholecystokinin depresses itch-as sociated scratching behavior in mice (2011)
  • Author(s): Fukamachi S, Mori T, Sakabe J-I, Shirai shi N, Kuroda E, Kobayashi M, Bito T, Kabashima K, Nakamura M, Tokura Y
  • Journal Title: J I nvest Dermatol Volume: 131 Pages: 956-961
  • Peer Reviewed
• [Journal Article] Modulation of semaphorin 3A expression by calcium concentration and histamine in human keratinocytes and fib roblasts (2011)
  • Author(s): Fukamachi S, Bito T, Shiraishi N, Koba yashi M, Kabashima K, Nakamura M, T okura Y
  • Journal Title: J Dermatol Sci Volume: 62 Pages: 118-123
  • Peer Reviewed
• [Journal Article] Efficacy of combined topical treatment of acne vul garis with adapalene and nadifloxacin : A randomized study (2011)
  • Author(s): Kobayashi M, Nakagawa T, Fukamachi K, Nakamura M, Tokura Y
  • Journal Title: J Dermatol Volume: 38 Pages: 1163-1166
  • NAID: 10031147162
  • Peer Reviewed
• [Journal Article] Downmodulatory effects of cetirizine and levocetirizine on cytokine/chemokine production and C D54 expression in keratinocytes (2011)
  • Author(s): Kobayashi M, Tokura Y
  • Journal Title: J Derm atol Volume: 38 Pages: 717-719
  • NAID: 10031147074
  • Peer Reviewed
• [Journal Article] Characterization of Peripheral Natural Killer Cells and their Reduction in Drug-induce d Hyper-sensitivity Syndrome (2011)
  • Author(s): Sugita K, Kabashima K, Tokura Y
  • Journal Title: Acta Der m Venereol Volume: 92 Pages: 83-84
  • Peer Reviewed
• [Journal Article] Increased expression of mRNAs for I L-4, IL-17, IL-22 and IL-31 in skin lesi ons of subacute and chronic forms of pr urigo (2011)
  • Author(s): Park K, Mori T, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 21 Pages: 135-136
  • Peer Reviewed
• [Journal Article] Inflammatory cytokine expression in the skin lesions of tumour necrosis factor receptor-associated periodic syndrome (2011)
  • Author(s): Ohmori S, Nakamura M, Hino R, Kobayashi M, Tokura Y
  • Journal Title: Rheumatology Volume: 51 Pages: 196-199
  • Peer Reviewed
• [Journal Article] High-Mobility Group Box 1 Protein(HMGB1) as a N ovel Diagnostic Tool for Toxic Epiderma l Necrolysis and Stevens-Johnson Syndro me (2011)
  • Author(s): Nakajima S, Watanabe H, Tohyama M, Sugita K, Iijima M, Hashimoto K, Tokur a Y, Nishimura Y, Doi H, Tanioka M, Miyachi Y, Kabashima K
  • Journal Title: Arch Dermatol Volume: 147 Pages: 1110-1112
  • Peer Reviewed
• [Journal Article] Epiletic seiz ures and cholinergic urticaria with gener alized hypohidrosis and anhidrosis (2011)
  • Author(s): Sawada Y, Bito T, Kabashia R, Sugita K, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 21 Pages: 99-100
  • Peer Reviewed
• [Journal Article] A c ase of cholinergic urticaria associated wit h acquired generalized hypohidrosis and reduced acetylcholine receptors : cause an d effect? (2011)
  • Author(s): Nakamizo S, Kurosawa M, Sawada Y, T okura Y, Miyachi Y, Kabashima K
  • Journal Title: Clin Exp Dermatol Volume: 36 Pages: 559-560
  • Peer Reviewed
• [Journal Article] Epithelial-mesenchymal transition in the skin (2011)
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: J Dermatol Sci Volume: 61 Pages: 7-13
  • NAID: 10030889466
  • Peer Reviewed
• [Journal Article] The type of skin eruptions is an independent prognostic indicator for adult T-cell leukemia/lymphoma (2011)
  • Author(s): Sawada Y, Hino R, Hama K, Ohmori S, Fueki H, Yamada S, Fukamachi S, Tajiri M, Kumo R, Yoshioka M, Nakashima D, Sugita K, Yoshiki R, Shimauchi T, Mori T, Izu K, Kobayashi M, Nakamura M, Tokura Y
  • Journal Title: Blood Volume: 117 Pages: 3961-3967
  • Peer Reviewed
• [Journal Article] Topical cholecystokinin depresses itch-associated scratching behavior in mice (2011)
  • Author(s): Fukamachi s, Mori T, Sakabe J-I, Shiraishi N, Kuroda E, Kobayashi M, Bito T, Kabashima K, Nakamura M, Tokura Y
  • Journal Title: J Invest Dermatol Volume: 131 Pages: 956-961
  • Peer Reviewed
• [Journal Article] Modulation of semaphorin 3A expression by calcium concentration and histamine in human keratinocytes and fibroblasts (2011)
  • Author(s): Fukamachi S, Bito T, Shiraishi N, Kobayashi M, Kabashima K, Nakamura M, Tokura Y
  • Journal Title: J Dermatol Sci Volume: 62 Pages: 118-123
  • NAID: 10030890103
  • Peer Reviewed
• [Journal Article] Inhibition of epidermal growth factor receptor and PI3K/Akt signaling suppresses cell proliferation and survival through regulation of Stat3 activation in human cutaneous squamous cell carcinoma (2011)
  • Author(s): Bito T, Sumita N, Ashida M, Budiyanto A, Ueda M, Ichihashi M, Tokura Y, Nishigori C
  • Journal Title: J Skin Cancer Volume: 2011 Pages: 874571-874571
  • Peer Reviewed
• [Journal Article] Efficacy of combined topical treatment of acne vulgaris with adapalene and nadifloxacin : A randomized study (2011)
  • Author(s): Kobayashi M, Nakagawa T, Fukamachi K, Nakamura M, Tokura Y
  • Journal Title: J Dermatol Volume: 38 Pages: 1163-1166
  • NAID: 10031147162
  • Peer Reviewed
• [Journal Article] High levels of activation-induced cytidine deaminase expression in adult T-cell leukaemia/lymphoma (2011)
  • Author(s): Nakamura M, Sugita K, Sawada Y, Yoshiki R, Hino R, Tokura Y
  • Journal Title: Br J Dermatol Volume: 165 Issue: 2 Pages: 437-439
  • DOI: 10.1111/j.1365-2133.2011.10342.x
  • Peer Reviewed
• [Journal Article] Elevated expression of activation-induced cytidine deaminase in T and NK cells from patients with chronic active Epstein-Barr virus infection (2011)
  • Author(s): Nakamura M, Iwata S, Kimura H, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 21 Pages: 780-782
  • Peer Reviewed
• [Journal Article] Downmodulatory effects of cetirizine and levocetirizine on cytokine/chemokine production and CD54 expression in keratinocytes (2011)
  • Author(s): Kobayashi M, Tokura Y
  • Journal Title: J Dermatol Volume: 38 Pages: 717-719
  • NAID: 10031147074
  • Peer Reviewed
• [Journal Article] Circulating Th17 cell fluctuation in psoriatic patients treated with topical calcipotriol and betamethasone butyrate propionate (2011)
  • Author(s): Hino R, Kabashima R, Kawakami C, Sugita K, Nakamura M, Tokura Y
  • Journal Title: J Eur Acad Dermatol Venereol Volume: 25 Issue: 2 Pages: 242-244
  • DOI: 10.1111/j.1468-3083.2010.03714.x
  • Peer Reviewed
• [Journal Article] Therapeutic efficacy of mizoribine for discoid lupus erythematosus with normalized frequency of circulating T helper 17 cells (2011)
  • Author(s): Sugita K, Kabashima R, Kawakami C, Nakamura M, Tokura Y
  • Journal Title: Clin Exp Dermatol Volume: 36 Issue: 3 Pages: 315-317
  • DOI: 10.1111/j.1365-2230.2010.03971.x
  • Peer Reviewed
• [Journal Article] Characterization of Peripheral Natural Killer Cells and their Reduction in Drug-induced Hyper-sensitivity Syndrome (2011)
  • Author(s): Sugita K, Kabashima K, Tokura Y
  • Journal Title: Acta Derm Venereol Volume: 92 Pages: 83-84
  • Peer Reviewed
• [Journal Article] Increased expression of mRNAs for IL-4, IL-17, IL-22 and IL-31 in skin lesions of subacute and chronic forms of prurigo (2011)
  • Author(s): Park K, Mori T, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 21 Pages: 135-136
  • Peer Reviewed
• [Journal Article] Molecular Mapping of Lymph Node Metastases by Real-Time RT-PCR in Two Melanoma Patients (2011)
  • Author(s): Abe-Mukumoto S, Mori T, Sakabe JI, Fukamachi S, Nakamura M, Kabashima K, Tokura Y
  • Journal Title: J Dermatol Volume: 38 Issue: 12 Pages: 1202-1205
  • DOI: 10.1111/j.1346-8138.2011.01204.x
  • Peer Reviewed
• [Journal Article] High-Mobility Group Box 1 Protein (HMGB1) as a Novel Diagnostic Tool for Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome (2011)
  • Author(s): Nakajima S, Watanabe H, Tohyama M, Sugita K, Iijima M, Hashimoto K, Tokura Y, Nishimura Y, Doi H, Tanioka M, Miyachi Y, Kabashima K
  • Journal Title: Arch Dermatol Volume: 147 Pages: 1110-1112
  • Peer Reviewed
• [Journal Article] Multiple milia and comedones as a skin manifestation of systemic amyloidosis (2011)
  • Author(s): Funai N, Machida s, Ito T, Hirakawa s, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 21 Pages: 638-639
  • Peer Reviewed
• [Journal Article] High-dose Intravenous Immunoglobulin Monotherapy for Drug-induced Hypersensitivity Syndrome (2011)
  • Author(s): Kito Y, Ito T, Hashizume H, Tokura Y
  • Journal Title: Acta Derm Venereol Volume: 92 Pages: 100-101
  • Peer Reviewed
• [Journal Article] Raynaud's phenomenon, digital gangrene and hypergammaglobulinemic purpura occurring in a patient with IgG4-related disease (2011)
  • Author(s): Ikawa T, Kasuya A, Hirakawa S, Tokura Y
  • Journal Title: Br J Dermatol Volume: 165 Issue: 6 Pages: 1359-1366
  • DOI: 10.1111/j.1365-2133.2011.10609.x
  • Peer Reviewed
• [Journal Article] Superficial angiomyxoma on the scrotum of a child (2011)
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Pediatr Dermatol Volume: 28 Issue: 2 Pages: 200-201
  • DOI: 10.1111/j.1525-1470.2011.01389.x
  • Peer Reviewed
• [Journal Article] Angiolymphoid hyperplasia with eosinophilia on the leg successfully treated with Th2 cytokine inhibitor suplatast tonsilate (2011)
  • Author(s): Bito T, Kabashima R, Sugita K, Tokura Y
  • Journal Title: J Dermatol Volume: 38 Issue: 3 Pages: 300-302
  • DOI: 10.1111/j.1346-8138.2010.00990.x
  • Peer Reviewed
• [Journal Article] Cutaneous pseudolymphoma due to benidipine hydrochloride with massive infiltration of eosinophils (2011)
  • Author(s): Fukamachi S, Sugita K, Nakamura M, Tokura Y
  • Journal Title: J Dermatol Volume: 38 Pages: 935-936
  • NAID: 10030728214
  • Peer Reviewed
• [Journal Article] Epiletic seizures and cholinergic urticaria with generalized hypohidrosis and anhidrosis (2011)
  • Author(s): Sawada Y, Bito T, Kabashia R, Sugita K, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 21 Pages: 99-100
  • Peer Reviewed
• [Journal Article] Necrobiosis lipoidica of the scrotum (2011)
  • Author(s): Sawada Y, Mori T, Nakashima D, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 21 Pages: 98-99
  • Peer Reviewed
• [Journal Article] Recurrent annular erythema after thymectomy (2011)
  • Author(s): Sawada Y, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 21 Pages: 425-426
  • Peer Reviewed
• [Journal Article] Keloid exacerbation associated with adult T-cell leukemia/lymphoma cell infiltration (2011)
  • Author(s): Sawada Y, Mori T, Yamada S, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 21 Pages: 646-647
  • Peer Reviewed
• [Journal Article] Generalized fixed drug eruption caused by pazufloxacin (2011)
  • Author(s): Sawada Y, Nakamura M, Tokura Y
  • Journal Title: Acta Derm Venereol Volume: 91 Pages: 600-601
  • Peer Reviewed
• [Journal Article] Schwannomatosis presenting with large subcutaneous and retroperitoneal tumours (2011)
  • Author(s): Yoshizawa M, Sugita K, Haruyama S, Yoshiki R, Hino R, Bito T, Nakamura M, Tokura Y
  • Journal Title: Clin Exp Dermatol Volume: 36 Issue: 5 Pages: 555-557
  • DOI: 10.1111/j.1365-2230.2011.04018.x
  • Peer Reviewed
• [Journal Article] Atypical large bullae caused by herpes simplex in a patient with thymoma (2011)
  • Author(s): Fueki H, Sugita K, Sawada Y, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 21 Pages: 435-436
  • Peer Reviewed
• [Journal Article] Acquired poikiloderma associated with primary biliary cirrhosis (2011)
  • Author(s): Fueki H, Sugita K, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 21 Pages: 118-118
  • Peer Reviewed
• [Journal Article] Calcinosis cutis associated with primary Sjogren's syndrome ; strong expression of osteonectin and matrix Gla protein (2011)
  • Author(s): Fueki H, Hino R, Nakamura M, Tokura Y
  • Journal Title: Rheumatology (Oxford) Volume: 50 Pages: 2318-2320
  • Peer Reviewed
• [Journal Article] A case of cholinergic urticaria associated with acquired generalized hypohidrosis and reduced acetylcholine receptors : cause and effect? (2011)
  • Author(s): Nakamizo S, Kurosawa M, Sawada Y, Tokura Y, Miyachi Y, Kabashima K
  • Journal Title: Clin Exp Dermatol Volume: 36 Issue: 5 Pages: 559-560
  • DOI: 10.1111/j.1365-2230.2011.04015.x
  • Peer Reviewed
• [Journal Article] Sebaceous carcinoma arising at a chronic candidiasis skin lesion of apatient with keratitis-ichthyosis-deafness (KID) syndrome (2011)
  • Author(s): Kaku Y, Tanizaki H, Tanioka M, Sakabe J, Miyagawa-Hayashino A, Tokura Y, Miyachi Y, Kabashima K
  • Journal Title: Br J Dermatol Volume: 166 Issue: 1 Pages: 222-224
  • DOI: 10.1111/j.1365-2133.2011.10521.x
  • Peer Reviewed
• [Journal Article] Chromoblastomycosis Caused by Fonsecaea monophora (2011)
  • Author(s): 杉山由華, 鈴木陽子, 菅谷圭子, 戸倉新樹, 矢口貴志, 亀井克彦, 西村和子
  • Journal Title: Medical Mycology Journal Volume: 52 Issue: 3 Pages: 255-260
  • DOI: 10.3314/mmj.52.255
  • NAID: 10029466342
  • ISSN: 2185-6486, 2186-165X
  • Peer Reviewed
• [Journal Article] アトピー性皮膚炎に対するタクロリムス軟膏の使用経験-全身への外用療法による皮疹とQOLの改善- (2011)
  • Author(s): 伊豆邦夫, 森智子, 戸倉新樹
  • Journal Title: Progress in Medicine Volume: 31 Pages: 1573-1577
  • Peer Reviewed
• [Journal Article] 日光角化症とBowen病に対するメタルハライドランプを用いた光線力学両方(PDT)の治療効果の検討 (2011)
  • Author(s): 尾藤利憲, 大森俊, 吉澤真衣子, 春山護人, 深田雄宇, 川上千佳, 椛島利江子, 椋本祥子, 杉田和成, 吉木竜太郎, 日野亮介, 森智子, 小林美和, 中村元信, 戸倉新樹
  • Journal Title: 西日本皮膚科 Volume: 73 Pages: 260-265
  • Peer Reviewed
• [Journal Article] Circulating Th17 cell fluctuation in psoriatic patients treated with topical calcipotriol and betamethasone butyrate propionate (2011)
  • Author(s): Hino R, Kabashima R, Kawakami C, Sugita K, Nakamura M, Tokura Y
  • Journal Title: J Eur Acad Dermatol Vnereol Volume: 25 Pages: 242-244
  • Peer Reviewed
• [Journal Article] Inducible Nitric Oxide Synthase Downmodulates Contact Hypersensitivity by Suppressing Dendritic Cell Migration and Survival (2010)
  • Author(s): Sugita K, Kabashima K, Yoshiki R, Iken ouchi-Sugita A, Tsutsui M, Nakamura J, Yanagihara N, Tokura Y
  • Journal Title: J Inves t Dermatol Volume: 130 Pages: 464-471
  • Peer Reviewed
• [Journal Article] Comparison of skin barrier function and sensory nerve electric current perception threshold between IgE-high extrinsic and IgE-normal intrinsic types of atopic dermatitis (2010)
  • Author(s): Mori T, Ishida K, Mukumoto S, Yamada Y, Imokawa G, Kabashima K, Kobayas hi M, Bito T, Nakamura M, Ogasawara K, Tokura Y
  • Journal Title: Br J Dermatol Volume: 162 Pages: 83-90
  • NAID: 130004546888
  • Peer Reviewed
• [Journal Article] Involvement of Wnt signaling in dermal fibroblasts (2010)
  • Author(s): Kabashima K, Sakabe J-I, Yoshiki R, Ta bata Y, Kohno K, Tokura Y
  • Journal Title: Am J Pathol Volume: 176 Pages: 721-732
  • Peer Reviewed
• [Journal Article] Flaky tail mouse denotes human atopic dermatitis in the steady state and by to pical application with Dermatophagoides pteronyssimus extract (2010)
  • Author(s): Moniaga CS, Egawa G, Kawasaki H, Ch ikuma M, Honda T, Tanizaki H, Nakaji ma S, Matsuoka H, Kubo A, Tokura Y, Miyachi Y, Amagai M, Kabashima K
  • Journal Title: Am J Pathol Volume: 176 Pages: 2385-2393
  • Peer Reviewed
• [Journal Article] The mandatory role of IL-10-producing and OX40L-expresssing mature Langerhans cells in local UVB-induced immunosuppression (2010)
  • Author(s): Yoshiki R, Kabashima K, Sakabe J-I, Su gita K, Bito T, Nakamura M, Malissen B, Tokura Y
  • Journal Title: J Immunol Volume: 84 Pages: 5670-5677
  • Peer Reviewed
• [Journal Article] Ultraviolet light induces Stat3 acti vation in human keratinocytes and fibrob lasts through reactive oxygen species and DNA damage (2010)
  • Author(s): Bito T, Sumita N, Masaki T, Shirakawa T, Ueda T, Yoshiki R, Tokura Y, Nishig ori C
  • Journal Title: Exp Dermatol Volume: 19 Pages: 654-660
  • Peer Reviewed
• [Journal Article] Activated regulatory Tcells are the major Tcell type emigrating from the skin during a cutaneous immune response in mice (2010)
  • Author(s): Tomura M, Honda T, Tanizaki H, Otsuk a A, Egawa G, Tokura Y, Waldmann H, Hori S, Cyster JG, Watanabe T, Miyach i Y, Kanagawa O, Kabashima K
  • Journal Title: J Clin Invest Volume: 120 Pages: 883-893
  • Peer Reviewed
• [Journal Article] Cholinergic urticaria : Studies on the muscarinic cholinergic receptor M3 in the anhidrotic and hypohidrotic skin (2010)
  • Author(s): Sawada Y, Nakamura M, Bito T, Fukam achi S, Kabashima R, Sugita K, Hino R, Tokura Y
  • Journal Title: J Invest Dermatol Volume: 130 Pages: 2683-2686
  • Peer Reviewed
• [Journal Article] FTY720 regulates bone marrow egress of eosinop hils and modulates late phase skin reacti on in mice (2010)
  • Author(s): Sugita K, Kabashima K, Sakabe J-I, Yos hiki R, Tanizaki H, Tokura Y
  • Journal Title: Am J Pathol Volume: 177 Pages: 1881-1887
  • Peer Reviewed
• [Journal Article] Extrinsic and intrinsic types o f atopic dermatitis (2010)
  • Author(s): Tokura Y
  • Journal Title: J Dermatol Sci Volume: 58 Pages: 1-7
  • Peer Reviewed
• [Journal Article] Inducible Nitric Oxide Synthase Downmodulates Contact Hypersensitivity by Suppressing Dendritic Cell Migration and Survival (2010)
  • Author(s): Sugita K, Kabashima K, Yoshiki R, Ikenouchi-Sugita A, Tsutsui M, Nakamum J, Yanagihara N, Tokura Y
  • Journal Title: J Invest Dermatol Volume: 130 Pages: 464-471
  • Peer Reviewed
• [Journal Article] Food-dependent anaphylaxis with serum IgE immunoreactive to dairy products containing high-molecular-weight proteins (2010)
  • Author(s): Abe S, Kabashima K, Moriyama T, Tokura Y
  • Journal Title: J Dermatol Sci Volume: 57 Pages: 137-140
  • NAID: 10027399736
  • Peer Reviewed
• [Journal Article] Leukemic cutaneous T-cell lymphoma manifesting papuloerythroderma with CD3- CD4+ phenotype (2010)
  • Author(s): Shimauchi T, Sugita K, Nakamura M, Tokura Y
  • Journal Title: Acta Derm Venereol Volume: 90 Pages: 68-72
  • Peer Reviewed
• [Journal Article] Tumor cell expression of programmed cell death 1 is a prognostic factor for malignant melanoma (2010)
  • Author(s): Hino R, Kabashima K, Kato Y, Yagi H, Nakamura M, Honjo T, Okaza ki T Tokura Y
  • Journal Title: Cancer Volume: 116 Pages: 1757-1766
  • Peer Reviewed
• [Journal Article] Evaluation of toxicity and Stat3 activation induced by hydrogen peroxide exposure to the skin in healthy individuals (2010)
  • Author(s): IBito T, Izu K, Tokura Y
  • Journal Title: J Dermatol Sci Volume: 58 Pages: 157-159
  • NAID: 10027400961
  • Peer Reviewed
• [Journal Article] Flaky tail mouse denotes human atopic dermatitis in the steady state and by topical application with Dermatophagoides pteronyssimus extract (2010)
  • Author(s): Moniaga CS, Egawa G, Kawasaki H, Chikuma M, Honda T, Tanizaki H, Nakajima S, Matsuoka H, Kubo A, Tokura Y, Miyachi Y, Amagai M, Kabashima K
  • Journal Title: Am J Pathol Volume: 176 Pages: 2385-2393
  • Peer Reviewed
• [Journal Article] Expression of Snaill in the fibrotic dermis of postmenopausal frontal fibrosing alopecia : possible involvement of an epithelial-mesenchymal transition and a review of the Japanese patients (2010)
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Br J Dermatol Volume: 162 Pages: 1152-1154
  • Peer Reviewed
• [Journal Article] Ultraviolet light induces Stat3 activation in human keratinocytes and fibroblasts through reactive oxygen species and DNA damage (2010)
  • Author(s): Bito T, Sumita N, Masaki T, Shirakawa T, Ueda T, Yoshiki R, Tokura Y, Nishigori C
  • Journal Title: Exp Dermatol Volume: 19 Pages: 654-660
  • Peer Reviewed
• [Journal Article] Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice (2010)
  • Author(s): Tomura M, Honda T, Tanizaki H, Otsuka A, Egawa G, Tokura Y, Waldmann H, Hon S, Cyster JG, Watanabe T, Miyachi Y, Kanagawa O, Kabashima K
  • Journal Title: J Clin Invest Volume: 120 Pages: 883-893
  • Peer Reviewed
• [Journal Article] Fluctuation of blood and skin plasmacytoid dendritic cells in drug-induced hypers ensitivity syndrome (2010)
  • Author(s): Sugita K, Tohyama M, Watanabe M, Otsuka A, Nakajima S, Iijima M, Hashimoto K, Tokura Y, Miyachi Y, Kabashima K
  • Journal Title: J Allergy Clin Immunol Volume: 126 Pages: 408-410
  • Peer Reviewed
• [Journal Article] FTY720 regulates bone marrow egress of eosinophils and modulates late phase skin reaction in mice (2010)
  • Author(s): Sugita K, Kabashima K, Sakabe J-I, Yoshiki R, Tanizald H, Tokura Y
  • Journal Title: Am J Pathol Volume: 177 Pages: 1881-1887
  • Peer Reviewed
• [Journal Article] Palmar pseudolymphoma associated with herpes simplex infection (2010)
  • Author(s): Fukamachi S, Kimura T, Kobayashi M, Hino R, Nakamura M, Tokura Y
  • Journal Title: J Cutan Pathol Volume: 37 Pages: 808-811
  • Peer Reviewed
• [Journal Article] A novel missense mutation in the TRPS1 gene in a case of trichorhinophalangeal syndrome type I (TRPS1) with fish-like malodour (2010)
  • Author(s): Nakamura M, Sugita K, Tokura Y
  • Journal Title: J Eur Acad Dermatol Venereol Volume: 24 Pages: 358-359
  • Peer Reviewed
• [Journal Article] Drug eruption induced by IL-6 receptor inhibitor tocilizumab (2010)
  • Author(s): Yoshiki R, Nakamura M, Tokura Y
  • Journal Title: J Eur Acad Dermatol Venereol Volume: 24 Pages: 495-496
  • Peer Reviewed
• [Journal Article] Development of a Prominent Granulomatous Eruption after Interferon-gamma The rapy in a Patient with Mycosis Fungoides (2010)
  • Author(s): Haruyama S, Sugita K, Kawakami C, Nakamura M, Tokura Y
  • Journal Title: Acta Derm Venereol Volume: 90 Pages: 190-191
  • Peer Reviewed
• [Journal Article] Eruptive generalized granuloma annulare presenting with numerous micropapules (2010)
  • Author(s): Ine K, Kabashima K, Koga C, Kobavashi M, Tokura Y
  • Journal Title: Int J Dermatol Volume: 49 Pages: 104-105
  • Peer Reviewed
• [Journal Article] Ectopic extramammary Paget's disease : case report and literature reiew (2010)
  • Author(s): Sawada Y, Bito T, Kabashima R, Yoshiki R, Hino R, Nakamura M, Masanori S, Tokura Y
  • Journal Title: Acta Derm Venereol Volume: 90 Pages: 502-505
  • Peer Reviewed
• [Journal Article] Epidermolysis bullosa acquisita associated with psoriasis (2010)
  • Author(s): Kabashima R, Hino R, Bito T, Kabashima K, Nakamura M, Oyama B, Hashimoto T, Tokura Y
  • Journal Title: Acta Derm Venereol Volume: 90 Pages: 314-316
  • Peer Reviewed
• [Journal Article] Complete remission of metastatic malignant melanoma after surgery in association with development of systemic vitiligo (2010)
  • Author(s): Nishitani N, Bito T, Ikeda T, Tokura Y, Nishigori C
  • Journal Title: J Dermatol Volume: 37 Pages: 770-772
  • NAID: 10027067126
  • Peer Reviewed
• [Journal Article] A novel missense mutation in tumour necrosis factor receptor superfamily 1A (TNFRSF1A) gene found in tumour necrosis factor receptor-associated periodic syndrome (TRAPS) with high serum interleukin (IL)-22 (2010)
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 20 Pages: 1508-509
  • Peer Reviewed
• [Journal Article] Multiple pilomatricomas in association with 21-hydroxylase deficiency (2010)
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Pediatr Dermatol Volume: 27 Pages: 417-417
  • Peer Reviewed
• [Journal Article] Acta Derm Venereol (2010)
  • Author(s): Tanizaki H, Matsumura Y, Tokura Y, Miyachi Y, Kabashima K
  • Journal Title: A case of suppurative granuloma induced by insulin injection Volume: 90 Pages: 541-542
  • Peer Reviewed
• [Journal Article] Valsartan-induced Drug Eruption Followed by CD30+ Pesudolymphomatous Eruption (2010)
  • Author(s): Sawada Y, Yoshiki R, Kawakami C, Fukamachi S, Sugita K, Nakamura M, Tokura Y
  • Journal Title: Acta Derm Venereol Volume: 90 Pages: 521-522
  • Peer Reviewed
• [Journal Article] CD8+ CD56+ Mycosis Fungoides with an Indolent Clinical Behaviour : Case Report and Literature Review (2010)
  • Author(s): Sawada Y, Sugita K, Kabashima R, Hino R, Nakamura M, Koga C, Tokura Y
  • Journal Title: Acta Derm Venereol Volume: 90 Pages: 525-526
  • Peer Reviewed
• [Journal Article] Expression of Snaill in the vimentin-expressing squamous cell carcinoma mimic king atypical fibroxanthoma : possible involvement of an epithelial-mesenchymal transition (2010)
  • Author(s): Nakamura M, Sugita K, Tokura Y
  • Journal Title: J Eur Acad Dermatol Venereol Volume: 24 Pages: 1365-1366
  • Peer Reviewed
• [Journal Article] Acute hepatic failure secondary to extensive hepatic replacement by metastatic a melanotic melanoma : an autopsy case report (2010)
  • Author(s): Fusasaki T, Narita R, Hiura M, Abe S, Tabaru A, Hino R, Matsuyama A, Shimajiri S, Tokura Y, Sasaguri Y, Harada M
  • Journal Title: Clin J Gastroenterol Volume: 3 Pages: 327-331
  • Peer Reviewed
• [Journal Article] A case of laryngeal carcinoma in a young adult with dyskeratosis congenita (2010)
  • Author(s): Komune N, Hara T, Tamae A, Izu K, Tokura Y, Joe AK, Masuda M
  • Journal Title: Int J Clin Oncol Volume: 15 Pages: 428-432
  • NAID: 10026601597
  • Peer Reviewed
• [Journal Article] Generalized eruptive xanthoma with prominent deposition of naked chylomicrons : evidence for chylomicrons as the origin of urate-like crystals. (2010)
  • Author(s): Bito T, Kawakami C, Shimajiri S, Tokura Y
  • Journal Title: J Cutan Pathol Volume: 37 Pages: 1161-1163
  • Peer Reviewed
• [Journal Article] Chondrodermatitis of the auricle in patients with atopic dermatitis (2010)
  • Author(s): Sawada Y, Nakamura M, Bito T, Haruyama S, Kabashima R, Sugita K, Kobayashi M, Kabashima K, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 20 Pages: 1813-814
  • Peer Reviewed
• [Journal Article] Angiolymphoid hyperplasia with eosinophilia occurring on the penis (2010)
  • Author(s): Ohmori S, Sugita K, Sawada Y, Hino R, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: 20 Pages: 545-546
  • Peer Reviewed
• [Journal Article] Erosive pustular dermatosis of the scalp and leg associated with myasthenia gravis : A possible pathogenetic role for neutrophil-stimulating cytokines and chemokines (2010)
  • Author(s): Sawada Y, Bito T, Kawakami C, Shimauchi T, Nakamura M, Tokura Y
  • Journal Title: Acta Derma Venereol Volume: 90 Pages: 652-653
  • Peer Reviewed
• [Journal Article] Extrinsic and intrinsic types of atopic dermatitis (2010)
  • Author(s): Tokura Y
  • Journal Title: J Dermatol Sci Volume: 58 Pages: 11-7
  • NAID: 10027400148
  • Peer Reviewed
• [Journal Article] Psorisis and other Th17-mediated skin diseases (2010)
  • Author(s): Tokura Y, Mori T, Hino R
  • Journal Title: J UOEH Volume: 32 Pages: 317-328
  • Peer Reviewed
• [Journal Article] J UOEH (2010)
  • Author(s): Haruyama S, Sugita K, Kawakami C, Nakamura M, Tokura Y
  • Journal Title: Spinal cord compression presumably due to metastasized cutaneous squamous cell carcinoma to the thoracic spine Volume: 32 Pages: 155-159
  • Peer Reviewed
• [Journal Article] High responses of peripheral lymphocytes to mosquito salivary gland extracts in patients with Wells' syndrome (2010)
  • Author(s): Koga C, Sugita K, Kabashima K, Matsuoka H, Nakamura M, Tokura Y
  • Journal Title: J Am Acad Dermatol Volume: 63 Pages: 160-161
  • Peer Reviewed
• [Journal Article] 本邦に必要とされる専属産業医数:事業所・企業統計調査(総務省統計局経済基本構造統計課)から推計 (2010)
  • Author(s): 一瀬豊日, 中村早人, 戸倉新樹
  • Journal Title: 産業医科大学雑誌 Volume: 32 Pages: 73-81
  • NAID: 110007588850
  • Peer Reviewed
• [Journal Article] 塩酸オロパタジン内服によるアトピー性皮膚炎患者の血中サブSタンスPとTh17細胞割合への影響 (2010)
  • Author(s): 椛島利江子, 尾藤利憲, 田尻真貴子, 川上千佳, 深町晶子, 吉木竜太郎, 杉田和成, 日野亮介, 森智子, 小林美和, 中村元信, 戸倉新樹
  • Journal Title: 西日本皮膚科 Volume: 72 Pages: 159-161
  • Peer Reviewed
• [Journal Article] 月経に関連した外陰部皮膚症状に関するアトピー性皮膚炎患者へのアンケート調査 (2010)
  • Author(s): 小林美和, 戸倉新樹, 佐藤紀子, 高木豊, 北原隆, 武馬吉則, 河崎宏典
  • Journal Title: 西日本皮膚科 Volume: 72 Pages: 385-389
  • NAID: 10026637000
  • Peer Reviewed
• [Journal Article] ベシル酸ベポタスチン内服によるアトピー性皮膚炎患者の止痒効果とTh17細胞,Th2細胞の変動 (2010)
  • Author(s): 椛島利江子, 尾藤利憲, 日野亮介, 中村元信, 戸倉新樹
  • Journal Title: Progress in Medicine Volume: 30 Pages: 2229-2232
  • Peer Reviewed
• [Journal Article] ロキシスロマイシンの皮膚免疫調整作用 (2010)
  • Author(s): 小林美和, 吉木竜太郎, 坂部純一, 中村元信, 戸倉新樹
  • Journal Title: 皮膚の科学 Volume: 9 Pages: 17-20
  • Peer Reviewed
• [Journal Article] ミゾリビン内服が有効であった慢性苔癬状枇糠疹 (2010)
  • Author(s): 杉田和成, 椛島利江子, 中村元信, 戸倉新樹
  • Journal Title: 日本皮膚アレルギー・接触皮膚炎学会雑誌 Volume: 4 Pages: 47-50
  • Peer Reviewed
• [Journal Article] 発症から40年以上経過した皮膚疣状結核 (2010)
  • Author(s): 深町晶子, 川上千佳, 戸倉新樹
  • Journal Title: 皮膚病診療 Volume: 32 Pages: 259-262
  • Peer Reviewed
• [Journal Article] 上腕に商事,懸垂状外観を呈した巨大メルケル細胞癌 (2010)
  • Author(s): 椛島利江子, 尾藤利憲, 春山護人, 椋本祥子, 吉木竜太郎, 中村元信, 山本修, 戸倉新樹
  • Journal Title: Skin Cancer Volume: 25 Pages: 38-41
  • Peer Reviewed
• [Journal Article] Birt-Hogg-Dube症候群 (2010)
  • Author(s): 田尻真貴子, 永田貴久, 山下淳二, 三宅大我, 戸倉新樹
  • Journal Title: 西日本皮膚科 Volume: 72 Pages: 567-568
  • NAID: 130004475375
  • Peer Reviewed
• [Journal Article] 全身に白斑を伴った転移性悪性黒色腫の寛解例 (2010)
  • Author(s): 西谷奈生, 尾藤利憲, 池田哲也, 戸倉新樹, 錦織千佳子
  • Journal Title: Skin Cancer Volume: 25 Pages: 141-144
  • NAID: 10027731588
  • Peer Reviewed
• [Journal Article] 両上肢対称性に生じた線状強皮症の1例 (2010)
  • Author(s): 大森峻, 島内隆寿, 中村元信, 戸倉新樹
  • Journal Title: 日小児皮会雑誌 Volume: 29 Pages: 1155-117
  • NAID: 10027698483
  • Peer Reviewed
• [Journal Article] 薬剤アレルギーにおけるDLST (2010)
  • Author(s): 戸倉新樹, 深町晶子, 杉田和成
  • Journal Title: 臨床免疫・アレルギー科 Volume: 53 Pages: 278-283
  • Peer Reviewed
• [Journal Article] 皮疹の診かたとその記載法 (2010)
  • Author(s): 戸倉新樹
  • Journal Title: 小児科 Volume: 51 Pages: 536-541
  • Peer Reviewed
• [Journal Article] 小児アトピー性皮膚炎患者に対するセチリジンの有効性と安全性:文献的考察と一例報告 (2010)
  • Author(s): 戸倉新樹
  • Journal Title: アレルギー・免疫 Volume: 17 Pages: 142-149
  • NAID: 40017113912
  • Peer Reviewed
• [Journal Article] アトピー性皮膚炎の二大分別を考慮したかゆみ治療の新たな話題 (2010)
  • Author(s): 戸倉新樹
  • Journal Title: Medico Volume: 41 Pages: 194-198
  • Peer Reviewed
• [Journal Article] 内因性アトピーと外因性アトピー (2010)
  • Author(s): 戸倉新樹, 椛島利江子
  • Journal Title: アレルギーの臨床 Volume: 401 Pages: 404-409
  • Peer Reviewed
• [Journal Article] ロキシスロマイシンによるケラチノサイトのTh2ケモカイン産生抑制およびTh2細胞のケモカインケモカインレセプターの発現抑制 (2010)
  • Author(s): 小林美和, 島内隆寿, 日野亮介, 戸倉新樹
  • Journal Title: 皮膚の科学 Volume: 9 Pages: 1-5
  • Peer Reviewed
• [Journal Article] 乾癬のサイトカイン異常update (2010)
  • Author(s): 戸倉新樹
  • Journal Title: MB Derma Volume: 169 Pages: 9-14
  • Peer Reviewed
• [Journal Article] 蚊刺過敏症の背後に隠れるEBウイルス関連NK細胞リンパ増殖性疾患 (2010)
  • Author(s): 戸倉新樹
  • Journal Title: 皮膚アレルギーフロンティア Volume: 8 Pages: 85-89
  • Peer Reviewed
• [Journal Article] アトピー性皮膚炎:バリア異常とアレルギー.第38回日本アレルギー学会専門医教育セミナー (2010)
  • Author(s): 戸倉新樹
  • Journal Title: 日本アレルギー学会編 Pages: 23-27
  • Peer Reviewed
• [Journal Article] 貴方も名医:肥満細胞症 (2010)
  • Author(s): 笛木はるな, 戸倉新樹
  • Journal Title: Clinic Magazine Volume: 493
  • Peer Reviewed
• [Journal Article] 薬剤アレルギーにおけるDLST (2010)
  • Author(s): 戸倉新樹
  • Journal Title: マルホ皮膚科セミナー放送内容集 Volume: 207 Pages: 9-13
  • Peer Reviewed
• [Journal Article] 乾癬・アトピー性皮膚炎と免疫 (2010)
  • Author(s): 戸倉新樹
  • Journal Title: 日皮会誌 Volume: 120 Pages: 2175-2180
  • NAID: 130004708705
  • Peer Reviewed
• [Journal Article] 職業性皮膚疾患NAVI (2010)
  • Author(s): 戸倉新樹
  • Journal Title: デルマ倶楽部 Volume: 9 Pages: 5-6
  • NAID: 10024323288
  • Peer Reviewed
• [Journal Article] いま,接触皮膚炎は.皮膚アレルギーコンパクトセミナー (2010)
  • Author(s): 戸倉新樹, 宮地良樹
  • Volume: 6
  • Pages: 4-7
  • Peer Reviewed
• [Journal Article] Rosa cea-like demodicosis mimicking cutaneou s lymphoma
  • Author(s): Kito Y, Hashizume H, Tokura Y
  • Journal Title: Acta Derm Venereol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Haemodialysis-induced pseudoporphyria successfully treated with glutathione
  • Author(s): Kasuya A, Hashizume H, Tokura Y
  • Journal Title: Eur J Dermatol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Pathogenesis of alopecia areata : why does alopecia areata develop in a round pattern?
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Exp Dermatol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Decreased expression of homeostatic chemokine receptors in intravascular large B-cell lymphoma : A study of three cases
  • Author(s): Kasuya A, Fujiyama T, Shirahama S, Hashizume H, Tokura Y
  • Journal Title: Eur J Dermatol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Blocking of CTLA-4 on lymphocytes improves the sensitivity of lymphocyte transformation test in a patient with nickel allergy
  • Author(s): Sugita K, Kabashima K, Sawada Y, Haruyama s, Yoshioka M, Mori T, Ogasawara K, Tokura Y
  • Journal Title: Eur J Dermatol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Rosacea-like demodicosis mimicking cutaneous lymphoma
  • Author(s): Kito Y, Hashizume H, Tokura Y
  • Journal Title: Acta Derm Venereol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Histiocytoid Sweet's syndrome associated with t(9;22)(q34;q11)-positive chronic myelogenous leukemia : Immature granulocytic origin of histiocytic cells
  • Author(s): Kasuya A, Fujiyama T, Hashizume H, Inuzuka M, Tokura Y
  • Journal Title: Int J Dermatol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Acute onset disseminated superficial porokeratosis associated with exacerbation of diabetes mellitus due to development of anti-insulin antibodies
  • Author(s): Nakamura M, Fukamachi s, Tokura Y
  • Journal Title: Dermatoendocrinol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Congenital onychodysplasia of the index finger in a child with meconium aspiration syndrome
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Int J Dermatol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Methylmalonic aciduria presenting with recurrent multiple molluscum contagiosum lesions
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Dermatoendocrinol Volume: (in press)
  • Peer Reviewed
• [Journal Article] A high serum concentration of chemerin in pustular dermatitis paradoxically induced by etanercept
  • Author(s): Sawada Y, Nakamura M, Hama K, Hino R, Tokura Y
  • Journal Title: J Am Acad Dermatol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Occupational skin cancer arising in a patient with a high frequency of circulating regulatory T cells
  • Author(s): Ohmori S, Mori T, Haruyama S, Sawada Y, Hino R, Nakamura M, Tokura Y
  • Journal Title: Int J Dermatol Volume: (in press)
  • Peer Reviewed
• [Journal Article] Increased circulating Th17 frequencies and serum IL-22 levels in patients with acute generalized exanthematous pustulosis
  • Author(s): Kabashima R, Sugita K, Sawada Y, Hino R, Nakamura M, Tokura Y
  • Journal Title: J Eur Acad Dermatol Venereol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Acute onset disseminated superficial porokeratosis associated with exacerbation of diabetes mellitus due to development of anti-insulin antibodies
  • Author(s): Nakamura M, Fukamachi S, Tokura Y
  • Journal Title: Dermatoendocrinol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Connexin 26 (GJB2) mutations in keratitis-ichthyosis-deafness (KID) syndrome developing squamous cell caricinoma
  • Author(s): Sakabe JI, Yoshiki R, Sugita K, Haruyama S, Sawada Y, Kabashima R, Bito T, Nakamura M, Tokura Y
  • Journal Title: J Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Occupational skin cancer arising in a patient with a high frequency of circulating regulatory T cells
  • Author(s): Ohmori S, Mori T, Haruyama S, Sawada Y, Hino R, Nakamura M, To Kura Y
  • Journal Title: Int J Dermatol Volume: (提出済)
  • Peer Reviewed
• [Journal Article] Alopecia universalis...
  • Author(s): Kabashima R, Nakamura M, Tokura Y
  • Journal Title: Acta Derma Venereol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Prostanoid receptors as possible targets for anti-allergic drugs : Recent advances in prostanoids on allergy and immunology
  • Author(s): Honda T, Tokura Y, Miyachi Y, Kabashima K
  • Journal Title: Current Drug Targets Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Skin, Drug and Chemical Reactions
  • Author(s): Alenius H, Roberts DW, Tokura Y, Lauerma A, Patlewicz, Roberts MS
  • Journal Title: Drug Discovery Today Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Pathogenesis of alopecia areata : why does alopecia areata develop in a round pattern?
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Exp Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Expression of SNAI1 and TWIST1 in the eccrine glands of systemic sclerosis patients : possible involvement of epithelial-mesenchymal transition in the pathogenesis
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Br J Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Congenital onychodysplasia of the index finger in a child with meconium aspirati on syndrome
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Int J Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Systemic cholesterol embolization syndrome in a patient positive for anti-cardiolip in antibody
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Dermatoendocrinol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Methylmalonic aciduria presenting with recurrent multiple molluscum contagiosum lesions
  • Author(s): Nakamura M, Tokura Y
  • Journal Title: Dermatoendocrinol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Epiletic seizures and cholinergic urticaria with generalized hypohidrosis and anhidrosis
  • Author(s): Sawada Y, Bito T, Kabashia R, Sugita K, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Necrobiosis lipoidica of the scrotum
  • Author(s): Sawada Y, Mori T, Nakashima D, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Acquired poikiloderma associated with primary biliary cirrhosis
  • Author(s): Fueki H, Sugita K, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Schwannomatosis presenting with large subcutaneous and retroperitoneal tumours : report of a case and review of the literature
  • Author(s): Yoshizawa M, Sugita K, Hariyama S, Yoshiki R, Hino R, Bito T, Nakamura M, Tokura Y:
  • Journal Title: Clin Exp Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] A case of cholinergic urticaria associated with acquired generalized hypohidrosis and reduced acetylcholine receptors : cause and effect?
  • Author(s): Nakamizo S
  • Journal Title: Clin Exp Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Molecular Mapping of Lymph Node Metastases by Real-Time RT-PCR in Two Melanoma Patients
  • Author(s): Abe-Mukumoto S, Mori T, Sakabe JI, Fukamachi S, Nakamura M, Kabashima K, Tokura Y
  • Journal Title: J Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Therapeutic efficacy of mizoribine for discoid lupus erythematosus with normalized frequency of circulating T helper 17 cells
  • Author(s): Sugita K, Kabashima R, Kawakami C, Nakamura M, Tokura Y
  • Journal Title: Clin Exp Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Topical Cholecystokinin Depresses Itch-Associated Scratching Behavior in Mice
  • Author(s): Fukamachi S, Mori T, Sakabe J-I, Shiraishi N, Kuroda E, Kobayashi M, Bito T, Kabashima K, Nakamura M, Tokura Y
  • Journal Title: J Invest Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] The type of skin eruptions is an independent prognostic indicator for adult T-cell leukemia/lymphoma
  • Author(s): Sawada Y, Hino R, Hama K, Ohmori S, Fueki H, Yamada S, Fukamachi S, Tajiri M, Kumo R, Yoshioka M, Nakashima D, Sugita K, Yoshiki R, Shimauchi T, Mori T, Izu K, Kobayashi M, Nakamura M, Tokura Y
  • Journal Title: Blood Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Increased expression of mRNAs for IL-4, IL-17, IL-22 and IL-31 in skin lesions of subacute and chronic forms of prurigo
  • Author(s): Park K, Mori M, Nakamura M, Tokura Y
  • Journal Title: Eur J Dermatol Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] Downmodulatory effects of cetirizine and levocetirizine on cytokine/chemokine production and CD54 expression in keratinocytes
  • Author(s): Kobayashi M, Tokura Y
  • Journal Title: J Dermatol Volume: (印刷中)
  • NAID: 10031147074
  • Peer Reviewed
• [Journal Article] 紫外線による皮膚免疫能の抑制
  • Author(s): 戸倉新樹
  • Journal Title: 日皮会誌 Volume: (印刷中)
  • Peer Reviewed
• [Journal Article] 化学熱傷
  • Author(s): 戸倉新樹
  • Volume: (印刷中)
  • Peer Reviewed
• [Presentation] Skin barrier impairment is het erogeneous in atopic dermatitis (2011)
  • Author(s): Tokura Y
  • Organizer: The 36th Annual Meeting of the Japanese Socie ty for Investigative Dermatology
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 2011-12-10
• [Presentation] Skin barrier impairment is heterogeneous in atopic dermatitis (2011)
  • Author(s): Tokura Y
  • Organizer: The 36th Annual Meeting of the Japanese Society for Investigative Dermatology
  • Place of Presentation: Kyoto, Japan(招待講演)
  • Year and Date: 2011-12-10
• [Presentation] Atopic dermatitis and skin ba rrier in the extrinsic and intrinsic types (2011)
  • Author(s): Tokura Y
  • Organizer: The 37^<th> Annual Meeting of the Taiwane se Dermatological Association
  • Place of Presentation: Taipei, Taiwan.
  • Year and Date: 2011-11-26
• [Presentation] Atopic dermatitis and skin barrier in the extrinsic and intrinsic types (2011)
  • Author(s): Tokura Y
  • Organizer: The 37^<th> Annual Meeting of the Taiwanese Dermatological Association
  • Place of Presentation: Taipei, Taiwan(招待講演)
  • Year and Date: 2011-11-26
• [Presentation] 内因性アトピー性皮膚炎 (2011)
  • Author(s): 戸倉新樹
  • Organizer: 第62回日本皮膚科学会中部支部学術大会
  • Place of Presentation: 四日市
  • Year and Date: 2011-11-20
• [Presentation] 内因性アトピー性皮膚炎 (2011)
  • Author(s): 戸倉新樹
  • Organizer: 第62回日本皮膚科学会中部支部学術大会
  • Place of Presentation: 四日市(招待講演)
  • Year and Date: 2011-11-20
• [Presentation] 外来性物質に対する皮膚アレルギー反応機構 (2011)
  • Author(s): 戸倉新樹
  • Organizer: 第61回日本アレルギー学会秋季学術大会
  • Place of Presentation: 東京都
  • Year and Date: 2011-11-11
• [Presentation] 外来性物質に対する皮膚アレルギー反応機構 (2011)
  • Author(s): 戸倉新樹
  • Organizer: 第61回日本アレルギー学会秋季学術大会
  • Place of Presentation: 東京都(招待講演)
  • Year and Date: 2011-11-11
• [Presentation] 薬剤アレルギーにおけるT細胞,NK細胞,樹状細胞の変動 (2011)
  • Author(s): 杉田和成, 椛島健治, 中村元信, 戸倉新樹
  • Organizer: 第61回日本アレルギー学会秋季学術大会
  • Place of Presentation: 東京都(招待講演)
  • Year and Date: 2011-11-11
• [Presentation] 紫外線による免疫抑制を考える (2011)
  • Author(s): 戸倉新樹
  • Organizer: 日本皮膚科学会愛媛地方会佐山浩二教授就任記念第54回学術大会
  • Place of Presentation: 松山市(招待講演)
  • Year and Date: 2011-09-24
• [Presentation] Adult T-cell leukemia/lymphoma : Tree neoplasm with affinity to the skin (2011)
  • Author(s): Tokura Y
  • Organizer: International Immunodermatology Symposium (Post-ESDR 2011)
  • Place of Presentation: Heidelberg, Germany(招待講演)
  • Year and Date: 2011-09-12
• [Presentation] 成人T細胞性白血病/リンパ腫の皮疹型と予後の解析 (2011)
  • Author(s): 戸倉新樹, 澤田雄宇
  • Organizer: 第27回日本皮膚悪性腫瘍学会学術大会
  • Place of Presentation: 東京都(招待講演)
  • Year and Date: 2011-06-04
• [Presentation] Adult T-cell leukemia/lymphoma and HTLV-1. Cutaneous Lymphomas of Viral Origin (2011)
  • Author(s): Tokura Y
  • Organizer: 22^<nd> World Congress of Dermatology
  • Place of Presentation: Seoul, Korea(招待講演)
  • Year and Date: 2011-05-27
• [Presentation] Immunosuppression and Complications in the Disordered Axis of TNF-α and Th17 Cells (2011)
  • Author(s): Tokura Y
  • Organizer: 22^<nd> World Congress of Dermatology
  • Place of Presentation: Seoul, Korea(招待講演)
  • Year and Date: 2011-05-25
• [Presentation] Extrinsic and intrinsic types o f atopic dermatitis. Ancillary Meeting on Atopic Dermatitis (2011)
  • Author(s): Tokura Y
  • Organizer: 22^<nd> World Congress of Dermatology
  • Place of Presentation: Seoul, Korea
  • Year and Date: 2011-05-24
• [Presentation] Recent concept on the role of cutaneous dendritic cells in UVB-induce d immunosuppression (2011)
  • Author(s): Tokura Y
  • Organizer: 22^<nd> World Congress of Dermatology 2011
  • Place of Presentation: Seo ul, Korea
  • Year and Date: 2011-05-24
• [Presentation] Extrinsic and intrinsic types of atopic dermatitis. Ancillary Meeting on Atopic Dermatitis (2011)
  • Author(s): Tokura Y
  • Organizer: 22^<nd> World Congress of Dermatology 2011
  • Place of Presentation: Seoul, Korea(招待講演)
  • Year and Date: 2011-05-24
• [Presentation] Recent concept on the role of cutaneous dendritic cells in UVB-induced immunosuppression (2011)
  • Author(s): Tokura Y
  • Organizer: 22^<nd> World Congress of Dermatology 2011
  • Place of Presentation: Seoul, Korea(招待講演)
  • Year and Date: 2011-05-24
• [Presentation] Photoimmunology : sensitization and suppression (2011)
  • Author(s): Tokura Y
  • Organizer: Australasian Society for Dermatology Research 2011 Annual Scientific Meeting
  • Place of Presentation: Perth, Australia(招待講演)
  • Year and Date: 2011-05-19
• [Presentation] 新しい抗ヒスタミン薬とその特徴 (2011)
  • Author(s): 戸倉新樹
  • Organizer: 第74回日本皮膚科学会東京支部学術大会
  • Place of Presentation: ホテルグランパシフィックLEDAIBA(東京都)
  • Year and Date: 2011-02-12
• [Presentation] 外因性.内因性という分別はアトピー性皮膚炎に必要か (2011)
  • Author(s): 戸倉新樹
  • Organizer: 第16回アトピー性皮膚炎治療研究会シンポジウム
  • Place of Presentation: 小倉市
  • Year and Date: 2011-02-05
• [Presentation] 外因性・内因性という分別はアトピー性皮膚炎に必要か (2011)
  • Author(s): 戸倉新樹
  • Organizer: 第16回アトピー性皮膚炎治療研究会シンポジウム
  • Place of Presentation: 小倉市(招待講演)
  • Year and Date: 2011-02-05
• [Presentation] 外因性・内因性という分別はアトピー性皮膚炎に必要か (2011)
  • Author(s): 戸倉新樹
  • Organizer: 第16回アトピー性皮膚炎治療研究会シンポジウム
  • Place of Presentation: 北九州国際会議場(北九州市)
  • Year and Date: 2011-02-05
• [Presentation] The type of skin eruptions is an independent prognostic indicator for adult T cell leukemia/lymphoma (ATLL) (2011)
  • Author(s): Tokura Y
  • Organizer: 5^<th> International Symposium on the Biology and Immunology of Cutaneous Lymphomas
  • Place of Presentation: Berlin, Germany(招待講演)
  • Year and Date: 2011-01-15
• [Presentation] The type of skin eruptions is an independent prognostic indicator for adult T cell leukemia/lymphoma(ATLL). (2011)
  • Author(s): Tokura Y
  • Organizer: The 5^<th> International Symposium on the Biology and Immunology of Cutaneous Lymphomas
  • Place of Presentation: Kaiserin-Friedrich-Haus, Berlin
  • Year and Date: 2011-01-15
• [Presentation] Th17細胞と皮膚疾患 (2011)
  • Author(s): 戸倉新樹
  • Organizer: 第39回日本臨床免疫学会総会
  • Place of Presentation: 東京都
• [Presentation] Th17細胞と皮膚疾患 (2011)
  • Author(s): 戸倉新樹
  • Organizer: 第39回日本臨床免疫学会総会
  • Place of Presentation: 東京都(招待講演)
• [Presentation] Extrinsic and intrinsic types of atopic dermatitis (2010)
  • Author(s): Tokura Y
  • Organizer: The 35^<th> Annual Mee ting of Japanese Society for Investigative Dermatology
  • Place of Presentation: Wakayama Prefectural Cultural Hall, Wakayama
  • Year and Date: 2010-12-04
• [Presentation] Extrinsic and intrinsic types of atopic dermatitis (2010)
  • Author(s): Tokura Y
  • Organizer: The 35^<th> Annual Meeting of Japanese Society for Invest igative Dermatology
  • Place of Presentation: Wakayama Prefectural Cultural Hall, Wakayama
  • Year and Date: 2010-12-04
• [Presentation] 女性医師を痛めないために (2010)
  • Author(s): 戸倉新樹
  • Organizer: 皮膚科の女性医師を考える会:東部支部企画
  • Place of Presentation: 江陽グランドホテル(仙台市)
  • Year and Date: 2010-11-21
• [Presentation] 抗ヒスタミン薬の新しい展開 (2010)
  • Author(s): 戸倉新樹
  • Organizer: 第74回日本皮膚科学会東部支部学術大会
  • Place of Presentation: 江陽グランドホテル(仙台市)
  • Year and Date: 2010-11-21
• [Presentation] 二つのアトピー性皮膚炎:外因性と内因性 (2010)
  • Author(s): 戸倉新樹
  • Organizer: 日本香粧品学会第35回教育セミナー
  • Place of Presentation: ヤクルトホール(東京都)
  • Year and Date: 2010-11-12
• [Presentation] ベポタスチンベシル酸塩の皮膚炎抑制機序:角化細胞からTh17細胞まで亘る新観点 (2010)
  • Author(s): 戸倉新樹
  • Organizer: 第62回日本皮膚科学会西部支部学術大会
  • Place of Presentation: 倉敷市芸文館(倉敷市)
  • Year and Date: 2010-10-23
• [Presentation] アトピー性皮膚炎:バリア異常とアレルギー (2010)
  • Author(s): 戸倉新樹
  • Organizer: 第38回日本アレルギー学会専門医教育セミナー
  • Place of Presentation: 総評会館(東京都)
  • Year and Date: 2010-08-29
• [Presentation] 抗ヒスタミン薬の今日的話題を問う (2010)
  • Author(s): 戸倉新樹
  • Organizer: 第34回日本小児皮膚科学会
  • Place of Presentation: ひめぎんホール(松山市)
  • Year and Date: 2010-07-04
• [Presentation] 皮膚疾患とケモカイン (2010)
  • Author(s): 戸倉新樹
  • Organizer: 第75回日本インターフェロン・サイトカイン学会
  • Place of Presentation: 北九州国際会議場(北九州市)
  • Year and Date: 2010-06-25
• [Presentation] やさしいリンフォーマ (2010)
  • Author(s): 戸倉新樹
  • Organizer: 第26回日本皮膚悪性腫瘍学会学術大会
  • Place of Presentation: 京王プラザホテル(東京)
  • Year and Date: 2010-06-05
• [Presentation] ざ瘡治療ガイドラインに沿った最適な治療とは? (2010)
  • Author(s): 戸倉新樹
  • Organizer: 第26回に本臨床皮膚科医会総会・学術大会
  • Place of Presentation: ホテルグランパシフィックLEDAIBA(東京都)
  • Year and Date: 2010-05-29
• [Presentation] Psoriasis and Th17-mediated skin diseases (2010)
  • Author(s): Tokura Y
  • Organizer: Shanghai Immunodermatology Forum
  • Place of Presentation: Shanghai, China
  • Year and Date: 2010-05-20
• [Presentation] Association of autologous sweat allergy and metal allergy with the intrinsic type of atopic dermatitis (2010)
  • Author(s): Bito T, Kabashima R, Fukamachi S, Yoshiki R, Hino R, Mori T, Nichigon C, Tokura Y
  • Organizer: The 70^<th> Annual Meeting of Society for Investigative Dermatology
  • Place of Presentation: Hilton Atlanta Hotel, Atlanta, Georgia?
• [Presentation] The intrinsic type of atopic dermatitis shows normal barrier function, lack of filaggrin mutations, high percentage of Thl cells, and high frequency of metal allergy (2010)
  • Author(s): Kabashima R, Nakamura M, Kobayashi M, Bito T, Kabashima K, Nomura Y, Akiyama M, Shimizu H, Tokura Y
  • Organizer: The 70^<th> Annual Meeting of Society for Investigative Dermatology
  • Place of Presentation: Hilton Atlanta Hotel, Atlanta, Georgia?
• [Presentation] Classification of skin manifestations of adult T-cell leukemia/lymphoma useful for staging and predictive for prognosis (2010)
  • Author(s): Sawada Y, Hino R, Hama K, Nakamura M, Tokura Y
  • Organizer: The 70^<th> Annual Meeting of Society for Investigative Dermatology
  • Place of Presentation: Hilton Atlanta Hotel, Atlanta, Georgia?
• [Presentation] Diagnostic detection of micrometastasis to sentinel lymph nodes by real-time PCR analysis in malignant melanoma (2010)
  • Author(s): Mukumoto S, Hino R, Mori T, Sakabe J, Nakamura M, Tokura Y
  • Organizer: The 70^<th> Annual Meeting of Society for Investigative Dermatology
  • Place of Presentation: Hilton Atlanta Hotel, Atlanta, Georgia?
• [Presentation] Increased expression of activation-induced cytidine deaminase in chronic active Epstein-Barr virus infection leads to neoplastic development (2010)
  • Author(s): Nakamura M, Kimura H, Tokura Y
  • Organizer: The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
  • Place of Presentation: Wakayama Prefectural Cultural Hall, Wakayama?
• [Presentation] Epithelial-mesenchymal transition in skin fibrosis and tumor formation (2010)
  • Author(s): Nakamura M, Tokura Y
  • Organizer: The 40^<th> European Society of Dermatology Research Annual Meeting
  • Place of Presentation: Scandic Marina Congress Center, Helsinki, Finland
• [Presentation] Controlled delivery of T-box21 (T-bet) small interfering RNA (siRNA) using cationized gelatin ameliorates autoimmune alopecia (alopecia areata) in a C3H/FleJ mouse model (2010)
  • Author(s): Nakamura M, Tabata Y, Tokura Y
  • Organizer: The 14^<th> International Congress of Immunology
  • Place of Presentation: Kobe Convention Center Complex
• [Presentation] New approach for a hair follicle regeneration using mouse induced pluripotent stem cells (2010)
  • Author(s): Nakamura M, Tokura Y
  • Organizer: The 6^<th> World Congress of Hair Research
  • Place of Presentation: Cairns Convention Centre, Cairns, Australia?
• [Presentation] Spicular form titanium dioxide induces IL-1 alpha/beta production of keratinocytes (2010)
  • Author(s): Kobayashi M, Sakabe J, Nakamura M, Tokura Y
  • Organizer: The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
  • Place of Presentation: Wakayama Prefectural Cultural Hall, Wakayama?
• [Presentation] Inhibition of immediate and late-phase cutaneous reactions by blockade of D1-like dopamine receptors (2010)
  • Author(s): Mori T, Kabashima K, Kuroda E, Sakabe J, Fukamachi S, Kobayashi M, Nakajima S, Nakano K, Tanaka Y, Yamashita S, Tokura Y
  • Organizer: The 14th International Congress of immunology
  • Place of Presentation: Kobe Convention Center Complex?
• [Presentation] Increased expression of mRNAs for IL-4, IL-17, IL-22 and IL-31 in skin lesions of subacute and chronic forms of prurigo (2010)
  • Author(s): Mori T, Park K, Nakamura M, Tokura Y
  • Organizer: The First Eastern Asia Dermatology Congress
  • Place of Presentation: Hotel New Otani Hakata, Fukuoka
• [Presentation] Inhibition of immediate and late-phase cutaneous reactions by blockade of D1-like dopamine receptors (2010)
  • Author(s): Mori T, Kabashima K, Sakabe JI, Kuroda E, Fukamachi S, Kobayashi M, Nakajima S, Nakamura M, Tokura Y
  • Organizer: The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
  • Place of Presentation: Wakayama Prefectural Cultural Hall, Wakayama
• [Presentation] Local UVB-induced immunosuppression is mediated by IL-10 producing and OX40L-positive mature Langerhans cells. (2010)
  • Author(s): Yoshiki R, Kabashima K, Sakabe J, Sugita K, Bito T, Nakamura M, Tokura Y
  • Organizer: The 14th International Congress of Immunology
  • Place of Presentation: Kobe Convention Center Conplex, Kobe?
• [Presentation] A novel role of the distribution of plasmacytoid dendritic cells for HHV-6 reactivation in drug-induced hypersensitivity syndrome (2010)
  • Author(s): Sugita K, Tohyama M, Watanabe H, Iijima M, Hashimoto K, Miyachi Y, Tokura Y, Kabashima K
  • Organizer: The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
  • Place of Presentation: Wakayama Prefectural Cultural Hall, Wakayama
• [Presentation] Barrier function-based immunological differences between extrinsic and intrinsic types of atopic dermatitis (2010)
  • Author(s): Kabashima R, Nakamura M, Sakabe J, Fukamachi S, Sugita K, Hino R, Mori T, Kobayashi M, Bito T, Kabashima K, Nomura Y, Akiyama M, Shimizu H, Tokura Y
  • Organizer: The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
  • Place of Presentation: Wakayama Prefectural Cultural Hall, Wakayama?
• [Presentation] Classification of skin manifestations of adult T-cell leukemia/lymphoma (ATLL) useful for staging and predictive for prognosis (2010)
  • Author(s): Sawada Y, Hino R, Hama K, Nakamura M, Tokura Y.
  • Organizer: Society for Investigative Dermatology
  • Place of Presentation: Atlanta
• [Presentation] Classification of skin manifestations of adult T-cell leukemia/lymphoma (ATLL) useful for staging and predictive for prognosis (2010)
  • Author(s): Sawada Y, Hino R, Hama K, Nakamura M, Tokura Y.
  • Organizer: American Dermato-Epidemiology Network Annual meeting
  • Place of Presentation: Atlanta
• [Presentation] Classification of skin manifestations of adult T-cell leukemia/lymphoma (ATLL) useful for staging and predictive for prognosis (2010)
  • Author(s): Sawada Y, Hino R, Hama K, Nakamura M, Tokura Y.
  • Organizer: The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
  • Place of Presentation: Wakayama Prefectural Cultural Hall, Wakayama
• [Presentation] Heparin serves as a natural stimulant of inflammasome and exacerbates the symptoms of TRAPS. (2010)
  • Author(s): Ohmori S, Hino R, Nakamura M, Tokura Y
  • Organizer: The 40th Annual Meeting of the European Society for Dermatoloeical Research
  • Place of Presentation: Scandic Marina Congress Center, Helsinki?
• [Presentation] Angiolymphoid hyperplasia with eosinophilia occurring on the penis : case report and literature review. (2010)
  • Author(s): Ohmori S, Sugita K, Sawada Y, Hino R, Nakamura M, Tokura Y
  • Organizer: The First Eastern Asia Dermatology Congress
  • Place of Presentation: Hotel New Otani Hakata, Fukuoka
• [Presentation] Study on heparin as a natural stimulant of inflammasome. (2010)
  • Author(s): Ohmori S, Hino R, Nakamura M, Tokura Y
  • Organizer: The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
  • Place of Presentation: Wakayama Prefectural Cultural Hall, Wakayama
• [Presentation] PI3-kinase pathway regulates antigen-induced type2 cytokine production from basophils. (2010)
  • Author(s): Sakabe J, Kuroda E, Tokura Y
  • Organizer: The 14th International Congress of Immunology
  • Place of Presentation: Kobe Convention Center Conplex, Kobe
• [Presentation] The mandatory role of PI3-kinase pathway in IL-4 and IL-13 production by basophils stimulated with IgE and antigen. (2010)
  • Author(s): Sakabe J, Kuroda E, Nakamura M, Tokura Y
  • Organizer: The 40th European Society of Dermatological Research (ESDR) Meeting
  • Place of Presentation: Scandic Marina Congress Center, Helsinki
• [Presentation] The role of basophil-derived Th2 cytokines in super late phase reaction in vivo (2010)
  • Author(s): Sakabe J, Kuroda E, Nakamura M, Tokura Y
  • Organizer: The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
  • Place of Presentation: Wakayama Prefectural Cultural Hall, Wakayama
• [Presentation] Association of autologous sweat allergy and metal allergy with the intrinsic type of atopic dermatitis (2010)
  • Author(s): Bito T, Kabashima R, Fukamachi S, Yoshiki R, Hino R, Mori T, Nishigon C, Tokura Y
  • Organizer: SID 70^<th> Annual Meeting
  • Place of Presentation: Atlanta Hilton, Atlanta
• [Presentation] Analysis of autologous sweat in atopic, dermatitis patients with sweat allergy and/or metal allergy (2010)
  • Author(s): Bito T, Kabashima R, Hino R, Mori T, Horikawa T, Hirasawa N, Tokura Y, Nishigori C
  • Organizer: The First Eastern Asia Dermatology Congress (EADC)
  • Place of Presentation: Hotel New Otani Hakata, Fukuoka
• [Book] Hypersensitivity to mosquito bites and EBV (2011)
  • Author(s): Tokura Y
  • Publisher: MEDRANG
• [Book] 皮膚科臨床アセット1.アトピー性皮膚炎 (2011)
  • Author(s): 戸倉新樹
  • Publisher: 中山書店
• [Book] 皮膚疾患最新の治療2011-2012 (2011)
  • Author(s): 戸倉新樹
  • Total Pages: 117
  • Publisher: 南江堂
• [Book] 皮膚科診療カラーアトラス大系 (2011)
  • Author(s): 戸倉新樹
  • Publisher: 講談社
• [Book] 臨床医必携-全身とかゆみ (2011)
  • Author(s): 戸倉新樹
  • Publisher: 診断と治療社
• [Book] 高齢者の皮膚トラブルFAQ (2011)
  • Author(s): 戸倉新樹
  • Total Pages: 2
  • Publisher: 診断と治療社
• [Book] 皮膚科臨床アセット2.薬疹診療のフロントライン (2011)
  • Author(s): 戸倉新樹
  • Total Pages: 6
  • Publisher: 中山書店
• [Book] 皮膚悪性腫瘍取扱い規約第2版 (2011)
  • Author(s): 戸倉新樹
  • Total Pages: 6
  • Publisher: 金原出版
• [Book] 治療薬ハンドブック2011 (2011)
  • Author(s): 織茂弘志, 戸倉新樹
  • Publisher: じほう
• [Book] 皮膚科臨床アセット.1.アトピー性皮膚炎 (2011)
  • Author(s): 戸倉新樹
  • Publisher: 中山書店
• [Book] 皮膚科サブスペシャリティーシリーズ,1冊でわかる皮膚がん (2011)
  • Author(s): 島内隆寿, 戸倉新樹
  • Publisher: 文光堂
• [Book] 治療薬ハンドブック2010 (2010)
  • Author(s): 織茂弘志, 戸倉新樹(分担執筆)高久史麿(監修)
  • Publisher: じほう
• [Book] ガイドライン外来診療2010 (2010)
  • Author(s): 戸倉新樹(分担執筆)
  • Publisher: 日経メディカル開発
• [Book] 看護大辞典第2版 (2010)
  • Author(s): 戸倉新樹(分担執筆)
  • Total Pages: 7
  • Publisher: 医学書院
• [Book] 今日の治療指針第6版 (2010)
  • Author(s): 戸倉新樹(分担執筆)
  • Publisher: 医学書院
• [Book] 標準皮膚科学第9版 (2010)
  • Author(s): 戸倉新樹(分担執筆)
  • Publisher: 医学書院
• [Book] WHAT'S NEW in皮膚科学2010-2011 (2010)
  • Author(s): 礒田英華, 戸倉新樹(分担執筆)
  • Publisher: メディカルレビュー社
• [Book] 小児科臨床ピクシス17 (2010)
  • Author(s): 戸倉新樹(分担執筆)
  • Publisher: 中山書店
• [Book] ファーストステップ皮膚免疫学 (2010)
  • Author(s): 戸倉新樹
  • Publisher: 中外医学社
• [Book] 皮膚悪性腫瘍取扱い規約第2版 (2010)
  • Author(s): 戸倉新樹
  • Publisher: 金原出版
• [Book] からだと光の事典 (2010)
  • Author(s): 戸倉新樹
  • Publisher: 朝倉書店
• [Book] Hypersensitivity to mosquito bites and EBV
  • Author(s): Tokura Y
  • Publisher: 22^<nd> World Congress of Dermatology Special Book(印刷中)
• [Patent(Industrial Property Rights)] 皮膚疾患治療薬 (2009)
  • Inventor(s): 戸倉新樹・深町晶子
  • Industrial Property Rights Holder: 産業医科大学・浜松医科大学
  • Filing Date: 2009-10-23
• [Patent(Industrial Property Rights)] 皮膚疾患治療薬 (2009)
  • Inventor(s): 戸倉新樹
  • Industrial Property Rights Holder: 産業医科大学、戸倉新樹
  • Industrial Property Number: 2009-244528
  • Filing Date: 2009-10-23