Establishment of in situ functional neuroimaging for social Behavior and its application to psychiatry
| Project/Area Number |
22659209
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Psychiatric science
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| Research Institution | Gunma University |
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Principal Investigator |
FUKUDA Masato 群馬大学, 大学院・医学系研究科, 准教授 (20221533)
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| Co-Investigator(Kenkyū-buntansha) |
MIKUNI Masahiko 群馬大学, 大学院・医学系研究科, 教授 (00125353)
KAMEYAMA Masaki 群馬大学, 大学院・医学系研究科, 助教 (00455982)
TAKEI Yuichi 群馬大学, 医学部, 助教 (30455985)
UEHARA Toru 群馬大学, 健康支援総合センター, 准教授 (60303145)
NARITA Kosuke 群馬大学, 医学部, 講師 (70345677)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,180,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥480,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,100,000 (Direct Cost: ¥1,100,000)
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| Keywords | 統合失調症 / 気分障害 / 対人関係 / 近赤外線スペクトロスコピィ / 前頭極 / 脳・神経 / 脳神経疾患 / 前頭葉 / 対人行動 |
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| Research Abstract |
Brain substrates of social behavior were investigated using near-infrared spectroscopy (NIRS) just during the conversation. Frontal and temporal activations during the conversation were correlated positively with cooperativeness assessed with the NEO-PI-R and negatively with autistic trait assessed with the autism quotient (AQ) in healthy subjects, and were also negatively correlated with negative symptoms assessed with the PANSS in schizophrenia patients. These results demonstrate successful establishment of functional neuroimaging examination just during social behaviors, which can be called as "in situ neuroimaging".
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Report
(4 results)
Research Products
(96 results)
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[Journal Article] Associations among parenting experiences during childhood and adolescence, hypothalamus-pituitary-adrenal axis hypoactivity, and hippocampal gray matter volume reduction in young adults2012
Author(s)
Narita K, Fujihara K, Takei Y, Suda M, Aoyama Y, Uehara T, Majima T, Kosaka H, Amanuma M, Fukuda M, Mikuni M
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Journal Title
Hum Brain Mapp
Volume: 33
Issue: 9
Pages: 2211-2223
DOI
Related Report
Peer Reviewed
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[Journal Article] Different hemodynamic response patterns in the prefrontal cortical sub-regions according to the clinical stages of psychosis.2011
Author(s)
Koike S, Takizawa R, Nishimura Y, Takano Y, Takayanagi Y, Kinou M, Araki T, Harima H, Fukuda M, Okazaki Y, Kasai K.
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Journal Title
Schizophr Res
Volume: 132
Issue: 1
Pages: 54-61
DOI
Related Report
Peer Reviewed
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[Journal Article] Total and regional brain volume reductions due to the Syndrome of Irreversible Lithium-Effectuated Neurotoxicity (SILENT) : A voxel-based morphometric study2010
Author(s)
Ikeda Y, Kameyama M, Narita K, Takei Y, Suda M, Aoyama Y, Yuuki N, Sakurai N, Amanuma M, Fukuda M, Mikuni M
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Journal Title
Prog Neuro-Psychopharmacol Biol Psychiatry
Volume: 34
Pages: 244-246
Related Report
Peer Reviewed
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[Presentation] 波形の読み方の基礎2011
Author(s)
福田正人
Organizer
第1回NCNP光トポグラフィー判読セミナー
Place of Presentation
東京(招待講演)
Year and Date
2011-11-19
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