Optimization and individualization of breast cancer treatment using OS-MSP.
Project/Area Number |
22659231
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Single-year Grants |
Research Field |
General surgery
|
Research Institution | Osaka University |
Principal Investigator |
|
Project Period (FY) |
2010 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,300,000)
|
Keywords | メチル化 / GSTP1 / RASSF1A / FARβ2 / 14-3-3δ / 個別化 / 治療効果予測 / RARβ2 / Rassf1a / RARb / 予後予測 |
Research Abstract |
・OS-MSP, which can detect DNA methylation in serum sensitively, has been established. ・This method would be useful to predict the efficacy of neoadjuvant chemotherapy. ・DNA methylation and the amount of DNA from cancer in serum would be useful prognostic marker(submitted).
|
Report
(3 results)
Research Products
(5 results)