Analysis of reversible neuronal damage by using positron emission CT with fluoroacetate and cerebral revascularization under local anesthesia
| Project/Area Number |
22659256
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
OKAZAWA Hidehiko 福井大学, 高エネルギー医学研究センター, 教授 (50360813)
SHIGEMI Kenji 福井大学, 医学部, 教授 (00206088)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,340,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2012: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,000,000 (Direct Cost: ¥1,000,000)
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| Keywords | 脳血管障害 |
|---|
| Research Abstract |
We have already finished measurement of glial metabolism by using ^14C-fluoroacetate PET in the brain of normal rats and are preparing the measurement of glial metabolism in the ischemic brain in the same way by using rat middle cerebral artery occlusion models. We reported that [^64Cu] Diacetyl-bis (N4-methylthiosemicarbazone) (^62Cu-ATSM) PET was available to evaluate cerebral blood flow and metabolism by comparison study between normal volunteers and patients with cerebrovascular occlusive disease (Isozaki M, Kikuta K, Okazawa H et al : Feasibility of (62)Cu-ATSM PET for evaluation of brain ischaemia and misery perfusion in patients with cerebrovascular disease. Eur J Nucl Med Mol Imaging 38:1075-1082, 2011). As for the bypass under local anesthesia, we finish the study. Kaku et al reported the way of it (Kaku Yet al, J Neurosurg117:288-294, 2012）
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Report
(4 results)
Research Products
(85 results)
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[Journal Article] Diagnosis of moyamoya disease using 3-T MRI and MRA: value of cisternal moyamoya vessels.2012
Author(s)
Sawada T, Yamamoto A, Miki Y, Kikuta K, Okada T, Kanagaki M, Kasahara S, Miyamoto S, Takahashi JC, Fukuyama H, Togashi K
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Journal Title
Neuroradiology
Volume: 54(10)
Pages: 1089-97
NAID
Related Report
Peer Reviewed
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[Journal Article] Diagnosis of moyamoya disease using 3-T MRI and MRA: value of cisternal moyamoya vessels.2012
Author(s)
Sawada T, Yamamoto A, Miki Y, Kikuta KI, Okada T, Kanagaki M, Kasahara S, Miyamoto S, Takahashi JC, Fukuyama H, Togashi K
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Journal Title
Neuroradiology
Volume: 54(10)
Issue: 10
Pages: 1089-97
DOI
NAID
Related Report
Peer Reviewed
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[Journal Article] Identification of RNF213 as a susceptibility gene for moyamoyadisease and its possible role in vascular development2011
Author(s)
Liu W, Morito D, Takashima S, Mineharu Y, Kobayashi H, Hitomi T, Hashikata H, Matsuura N, Yamazaki S, Toyoda A, Kikuta K, Takagi Y, Harada KH, Fujiyama A, Herzig R, Krischek B, Zou L, Kim JE, Kitakaze M, Miyamoto S, Nagata K, Hashimoto N, Koizumi A
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Journal Title
NAID
Related Report
Peer Reviewed
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[Presentation]2011
Author(s)
菊田健一郎
Organizer
イーケプラ発売記念講演会
Place of Presentation
ホテルフジタ福井
Year and Date
2011-02-17
Related Report
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[Presentation] Bypass2010
Author(s)
菊田健一郎
Organizer
第69回日本脳神経外科学会総会モーニングセミナー
Place of Presentation
福岡国際会議場(九州)
Year and Date
2010-11-28
Related Report
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[Presentation] Bypass2010
Author(s)
菊田健一郎
Organizer
第69回日本脳神経外科学会総会モーニングセミナー
Place of Presentation
福岡国際会議場九州
Year and Date
2010-10-28
Related Report
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