| Project/Area Number |
22659258
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KUNIEDA Takeharu 京都大学, 医学研究科, 講師 (60609931)
三國 信啓 札幌医科大学, 医学部, 教授 (60314217)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,260,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,700,000 (Direct Cost: ¥1,700,000)
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| Keywords | 脳卒中 / 脳機能 |
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| Research Abstract |
In cases of tumor, located near supramarginal gyrus on the the language dominant side, the language function area was identified by a functional MRI and PET before the operation. And the superior longitudinal fasciculus was visualized by DTI tractography. With awake craniotomy technique, cortico-cortical evoked potential was recorded from adjacent and remote cortices to prove cortical network of language function. Evaluation and change of the language function were also analysed and compared after the operation repeatedly. The cases, who showed the interruption of superior longitudinal fasciculus on DTI tractography, showed prolonged conduction aphasia. This result indicated that this is due to obstacle condition of the superior longitudinal fasciculus.
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