| Project/Area Number |
22659265
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Orthopaedic surgery
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
NAKAGAWA Takumi 東京大学, 医学部附属病院, 講師 (90338385)
HIROTA Jinso 東京大学, 医学部附属病院, 助教 (30570733)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,290,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,600,000 (Direct Cost: ¥1,600,000)
|
|---|
| Keywords | 骨 / 軟骨代謝学 / 骨・軟骨代謝学 / 軟骨誘導リガンド |
|---|
| Research Abstract |
SNX19, a member of the SNX family of intracellular trafficking proteins, was highly expressed in chondrocytes through their differentiation. SNX19 enhanced the production of cartilage matrix like Col2a1 ; however, the molecular mechanism underlying the enhancement was still unrevealed
|
