| Project/Area Number |
22659348
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Prosthetic dentistry
|
|---|
| Research Institution | Niigata University |
|---|
Principal Investigator |
|
|---|
| Research Collaborator |
HAIDARIAN Nasri Mohammad Edris 新潟大学, 大学院, 学生
|
|---|
| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥3,240,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥540,000)
Fiscal Year 2012: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥900,000 (Direct Cost: ¥900,000)
|
|---|
| Keywords | 歯科補綴学一般 / 歯学 / 骨増成 / 生体材料 / インプラント / 増殖因子 |
|---|
| Research Abstract |
To establish a new technique of small scale bone augmentation for dental implant application without the reflection of periosteum, animal experiments were carried out using mixtures of Biopex-R (α-TCP) and several cytokines. Biopex-R and BMP-2, EGF, FGF-2, PDGF were mixed respectively and applied under rat calvarial periosteum using 18G needle. As a result of histological investigations, mixtures ofBiopex-R and BMP-2, EGF, PDGF showed better bone formation in comparison to Biopex-Ronly.
|
