| Project/Area Number |
22659354
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
MORITA Ikuo 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 (60100129)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAHAMA Kenichi 東京医科歯科大学, 大学院・医歯学総合研究科, 准教授 (60281515)
KOMAKI Motohiro 医科歯科大学, 大学院・医歯学総合研究科, 寄附講座教員 (30401368)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,220,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥420,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥1,400,000 (Direct Cost: ¥1,400,000)
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| Keywords | 再生医療 / 血管内皮細胞 / 血管再生 / 骨芽細胞 / 骨修復 / 血管新生 / 創傷治癒 / 印刷技術 / ポリエチレングリコール / 血管再建 / ペリサイト |
|---|
| Research Abstract |
To establish the angioplasty method using the novel printing technique, we developed a new substrate prepared by coating glass with polyethylene glycol to create a non-adhesive surface and subsequent photo-lithography to finely tune the adhesive property for efficient cell transfer. MicroCT analysis showed rapid and effective bone formation by the cell-equipped amniotic membrane. The cell-printing and transfer technology used to create the cell-equipped amniotic membrane was beneficial for the cell delivery system. Moreover, using scar model we developed the cell-equipped amnion membrane was examined.
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