Development of basic technology for tooth regeneration using iPS cells.
| Project/Area Number |
22659372
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,230,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥330,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,800,000 (Direct Cost: ¥1,800,000)
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|---|
| Keywords | 再生医療 / ヒトiPS細胞 / ヒト歯髄細胞 / 歯の再生 / iPS細胞 / 人工歯胚 |
|---|
| Research Abstract |
We planed to generate bioengineered tooth using iPS cells, and have performed fundamental research for it. We established iPS cells derived from human dental pulp cells and, analyzed stem cell marker expression. The results suggest that our iPS cells have features of stem cells.
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Report
(3 results)
Research Products
(50 results)
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[Journal Article] Differential roles of CCN family proteins during osteoblast differentiation : Involvement of Smad and MAPK signaling pathway2011
Author(s)
Kawaki H, Kubota S, Suzuki A, Suzuki M, Kohsaka K, Hoshi K, Fujii T, Lazar N, Ohgawara T, Maeda T, Perbal B, Takano-Yamamoto T, Takigawa M
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Journal Title
Bone
Volume: Vol.49
Pages: 975-989
Related Report
Peer Reviewed
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[Journal Article] Functional tooth regeneration using a bioengineered tooth unit as a mature organ replacement regenerative therapy2011
Author(s)
Oshima M, Mizuno M, Imamura A, Ogawa M, Yasukawa M, Yamazaki H, Morita R, Ikeda E, Nakao K, Takano-Yamamoto T, Kasugai S, Saito M, Tsuji T
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Journal Title
Related Report
Peer Reviewed
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[Journal Article] IL-12-and IL-18-mediated, nitric oxide-induced apoptosis in TNF-α-mediated osteoclastogenesis of bone marrow cells2011
Author(s)
Kitaura H, Fujimura Y, Yoshimatsu M, Kohara H, Morita Y, Aonuma T, Fukumoto E, Masuyama R, Yoshida N, Takano-Yamamoto T
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Journal Title
Calcif Tissue Int
Volume: Vol.89
Pages: 65-73
Related Report
Peer Reviewed
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