| Project/Area Number |
22659377
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Kagoshima University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OHMURE Haruhito 鹿児島大学, 大学院・医歯学総合研究科, 講師 (00404484)
NAGAYAMA Kunihiro 鹿児島大学, 医学部・歯学部附属病院, 助教 (60583458)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,290,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,600,000 (Direct Cost: ¥1,600,000)
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| Keywords | 胃 / 蠕動運動 / 胃排出能 / ブラキシズム / 咀嚼 / 睡眠時ブラキシズム / 胃食道逆流 / 胃電図 / 消化管運動 |
|---|
| Research Abstract |
Based on the hypothesis that gastric motility is related with bruxism that shows mastication-like movement, we conducted a randomized trial to compare the effects of mastication on gastric emptying and gastric myoelectrical activity under conditions that excluded the influences of food comminution, taste, and olfaction using^<13> C-acetate breath test in 14 healthy men who ingested a test meal with or without chewing gum. Gastric emptying was significantly delayed in the ingestion. Gastric myoelectrical activity was significantly suppressed during mastication and increased gradually in the post-mastication phase. A decrease in the high-frequency power of heart rate variability occurred coincidentally with gastric myoelectrical activity suppression. These findings suggest that initial gastric emptying is suppressed by mastication and that the suppression is caused by mastication-induced inhibition of gastric activity and a possibility that gastric motility is closely related with bruxism.
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