| Project/Area Number |
22659379
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Periodontal dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
YAMADA Satoru 大阪大学, 歯学部附属病院, 講師 (40359849)
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| Co-Investigator(Kenkyū-buntansha) |
NOZAKI Takenori 大阪大学, 大学院・歯学研究科, 助教 (30263304)
HASHIKAWA Tomoko 大阪大学, 大学院・歯学研究科, 助教 (00362682)
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| Research Collaborator |
KAJIKAWA Tetsuhiro 大阪大学, 歯学部附属病院, 医員 (90611252)
OZAKI Nobuhiro 大阪大学, 歯学部附属病院, 専修歯科医 (80632132)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥450,000)
Fiscal Year 2011: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,300,000)
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| Keywords | 歯周組織再生療法 / 歯周組織再生 / 歯根膜細胞 / 細胞移植 |
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| Research Abstract |
In order to develop novel minimal intervention therapies for periodontal tissue regeneration in the future, in this study, we investigated which methods are the most effective for introducing exogenous molecules into mesenchymal tissue stem cells for periodontal tissue regeneration. We found that the electroporation method is the most effective, especially utilizing periodontal ligament stem cells. We could conclude these information might be a first step to developing the future regeneration therapies.
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