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Cortical dysplasia detection from neonatal brain MR images usingintelligent medical image processing

Research Project

Project/Area Number 22680020
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Sensitivity informatics/Soft computing
Research InstitutionUniversity of Hyogo

Principal Investigator

KOBASHI Syoji  兵庫県立大学, 大学院・工学研究科, 准教授 (00332966)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥20,020,000 (Direct Cost: ¥15,400,000、Indirect Cost: ¥4,620,000)
Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2010: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
Keywords難治てんかん / 皮質形成異常 / 核磁気共鳴画像 / ソフトコンピューティング / 計算機画像診断支援 / 知的画像処理 / 新生児 / MRI / ファジィ論理 / 医用画像処理 / 子ども / てんかん / MR画像 / 新生児・幼児 / コンピュータ画像診断支援 / 脳 / 脳回
Research Abstract

Although subdural electrode has been used to detect cortical dysplasia, it cannot be applied to allpatients because of invasively . And, it cannot determine the boundary of cortical dysplasia legion. Thisstudy proposed a non-invasive cortical dysplasia detection and region segmentation method usingmagnetic resonance (MR) images. Firstly , this study proposed parenchyma segmentation method inbrain MR images based on fuzzy object model. Secondly , this study proposed a method of estimatingdegree cortical dysplasia using texture features and fractal dimension. The experimental results showedthe proposed method segmented the parenchymal region with a false-positive-volume-fraction of 0.75 %and detected cortical dysplasia with a mean sensitivity of about 90 %.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (36 results)

All 2013 2012 2011 2010 Other

All Journal Article (19 results) (of which Peer Reviewed: 19 results) Presentation (13 results) Book (1 results) Remarks (3 results)

  • [Journal Article] Fuzzy object models for newborn brain MR image segmentation2013

    • Author(s)
      Syoji Kobashi
    • Journal Title

      Proc. SPIE

      Volume: 8672 Pages: 86720J-86720J

    • DOI

      10.1117/12.2001161

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fuzzy object shape model for newborn brain MR image segmentation2012

    • Author(s)
      Aya Hashioka
    • Journal Title

      Proc. of the 6th International Conference on Soft Computing and Intelligent Systems and 13th International Symposium on Advanced Intelligent Systems

      Volume: 1 Pages: 1253-1258

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fuzzy Object Model Based Fuzzy Connectedness Image Segmentation for Newborn Brain MR Images2012

    • Author(s)
      Syoji Kobashi
    • Journal Title

      Proc. of 2012 IEEE Int. Conf. on Systems, Man and Cybernetics

      Volume: 1 Pages: 1422-1427

    • DOI

      10.1109/icsmc.2012.6377934

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Shape and appearance knowledge based brain segmentation for neonatal MR images2012

    • Author(s)
      Aya Hashioka
    • Journal Title

      Proc. of 2012 World Automation Cong

      Volume: 1

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A neonatal brainMR image template of 1 week newborn2011

    • Author(s)
      A. Hashioka, S. Kobashi, 他 4 名 , T.Ishikawa, and Y . Hata
    • Journal Title

      International Journal of Computer AssistedRadiology and Surgery

      Volume: V ol. 7(2) Pages: 273-280

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Cerebral ContourExtraction with Particle Method in NeonatalMR Images2011

    • Author(s)
      S. Kobashi, 他
    • Journal Title

      Journal of AdvancedComputational Intelligence and IntelligentInformatics

      Volume: V ol. 15 Pages: 362-369

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A neonatal brain MR image template of 1 week newborn2011

    • Author(s)
      A.Hashioka, S.Koashi, K.Kuramoto, Y.Wakata, K.Ando, R.Ishikura, T.Ishikawa, Y.Hata
    • Journal Title

      International Journal of Computer Assisted Radiology and Surgery

      Volume: 7(2) Issue: 2 Pages: 273-280

    • DOI

      10.1007/s11548-011-0646-5

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cerebral Contour Extraction with Particle Method in Neonatal MR Images2011

    • Author(s)
      S.Kobashi, D.Yokomichi, Y.Wakata, K.Ando, R.Ishikura, K.Kuramoto, S.Hirota, Y.Hata
    • Journal Title

      Journal of Advanced Computational Intelligence and Intelligent Informatics

      Volume: 15(3) Pages: 362-369

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A neonatal brain MR imagese template of 1 week new born2011

    • Author(s)
      A.Hashioka, S.Kobashi, K.Kuramoto, Y.Wakata, K.Ando, R.Ishikura, T.Ishikawa, S.Hirota, Y.Hata
    • Journal Title

      Int.Journal of Computer Assisted Radiology and Surgery

      Volume: 6(1) Pages: 346-346

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fractal Dimension Based Cortical Dysplasia Detection Using MR Images for Epilepsy Children2011

    • Author(s)
      S.Kobashi, N.Kawakami, Y.T.Kitamura, K.Shimono, K.Kuramoto, M.Taniike, Y.Hata
    • Journal Title

      Proc.of The 2011 International Conference on Image Processing, Computer Vision, and Pattern Recognition

      Pages: 467-473

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Particle Method for Sub-voxel Extraction of Cerebral Surface in Neonatal MR Images2011

    • Author(s)
      D.Yokomichi, S.Kobashi, Y.Wakata, K.Ando, R.Ishikura, K.Kuramoto, T.Ishikawa, S.Hirota, Y.Hata
    • Journal Title

      Proc.of The 2011 International Conference on Image Processing, Computer Vision, and Pattern Recognition

      Pages: 474-479

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neonatal brain MR image segmentation based on system-of-systems in engineering technology2011

    • Author(s)
      A.Hashioka, K.Yamaguchi, S.Kobashi, Y.Wakata, K.Ando, R.Ishikura, K.Kuramoto, T.Ishikawa, S.Hirota, Y.Hata
    • Journal Title

      Proc.of the 6th IEEE Int.Conf.on System of Systems Engineering

      Pages: 107-112

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Computer-Aided Diagnosis System of Systems for Neonatal Human Brain MR Images2010

    • Author(s)
      S.Kobashi, D.Yokomichi, K.Yamaguchi, K.Kuramoto, S.Imawaki, Y.Hata
    • Journal Title

      5th Int.Conference on Systems of Systems Engineering

      Volume: (CDROM)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Automated Fuzzy Logic Based Skull Stripping in Neonatal and Infantile MR Images2010

    • Author(s)
      K.Yamaguchi, Y.Fujimoto, S.Kobashi, Y.Wakata, R.Ishikura, K.Kuramoto, S.Imawaki, S.Hirota, Y.Hata
    • Journal Title

      2010 IEEE World Congress on Computational Intelligence

      Volume: (CDROM)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Statistical Quantification of Brain Shape Deformation with Homologous Brain Shape Modeling2010

    • Author(s)
      K.Yamaguchi, S.Kobashi, K.Kuramoto, Y.Kitamura, I.Mohri, S.Imawaki, M.Taniike, Y.Hata
    • Journal Title

      World Automation Congress

      Volume: (CDROM)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Study on Image Features Using Intensity Profile for Cortical Dysplasia Degrees Estimation2010

    • Author(s)
      N.Kawakami, S.Kobashi, K.Kuramoto, Y.T.Kitamura, K.Shimono, S.Imawaki, M.Taniike, Y.Hata
    • Journal Title

      World Automation Congress

      Volume: (CDROM)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Particle Method Based Sub-Voxel Cerebral Contour Extraction in Neonatal MR Images2010

    • Author(s)
      S.Kobashi, D.Yokomichi, K.Kuramoto, S.Imawaki, Y.Hata
    • Journal Title

      4th International Symposium on Computational Intelligence and Industrial Application

      Volume: (CDROM)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] P Estimation Method of Cortical Dysplasia Degree Using Neural Network in Pediatric Brain MR Images2010

    • Author(s)
      N.Kawakami, S.Kobashi, K.Kuramoto, Y.T.Kitamura, K.K.Shimono, S.Imawaki, M.Taniike, Y.Hata
    • Journal Title

      Int.Sympo.on Advanced Intelligent System

      Pages: 1399-1402

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] On a Voxel Based Morphometry Analysis in Neonatal Brain MR Images2010

    • Author(s)
      A.Hashioka, S.Kobashi, K.Kuramoto, Y.Wakata, K.Ando, R.Ishikura, S.Imawaki, S.Hirota, Y.Hata
    • Journal Title

      4th International Symposium on Computational Intelligence and Industrial Application

      Pages: 1393-1398

    • NAID

      130005019498

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] ソフトコンピューティング画像処理による MR 画像を用いたてんかん原性域検出2012

    • Author(s)
      小橋昌司, 他 6 名
    • Organizer
      映像情報 メディア学会技術報告
    • Place of Presentation
      埼玉
    • Year and Date
      2012-12-12
    • Related Report
      2012 Final Research Report
  • [Presentation] ソフトコンピューティング画像処理によるMR画像を用いたてんかん原性域検出2012

    • Author(s)
      小橋昌司
    • Organizer
      映像情報メディア学会技術報告
    • Place of Presentation
      埼玉工業大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] 新生児頭部MR画像からの脳領域法におけるファジィ物体モデルの検討2012

    • Author(s)
      橋岡亜弥
    • Organizer
      映像情報メディア学会技術報告
    • Place of Presentation
      埼玉工業大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] ファジィ物体形状モデルを用いた新生児頭部 MR 画像からの脳領域抽出法2012

    • Author(s)
      橋岡亜弥
    • Organizer
      第28回ファジィシステムシンポジウム
    • Place of Presentation
      名古屋工業大学
    • Related Report
      2012 Annual Research Report
  • [Presentation] 頭部輪郭形状を用いた新生児頭部MR画像からの大脳領域抽出法2011

    • Author(s)
      橋岡亜弥, 小橋昌司, 倉本圭, 若田ゆき, 安藤久美子, 石藏礼一, 石川智基, 廣田省三, 畑豊
    • Organizer
      平成23年度日本人間工学会関西支部大会
    • Place of Presentation
      神戸大学(兵庫県)
    • Year and Date
      2011-12-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新生児頭部MR画像からの粒子法によるサブボクセル精度での脳表抽出2011

    • Author(s)
      横道大督, 小橋昌司, 若田ゆき, 安藤久美子, 石藏礼一, 倉本圭, 石川智基, 廣田省三, 畑豊
    • Organizer
      第27回ファジィシステムシンポジウム
    • Place of Presentation
      福井大学(福井県)
    • Year and Date
      2011-09-14
    • Related Report
      2011 Annual Research Report
  • [Presentation] 新生児頭部 MR 画像を用いた脳形状正規化法2011

    • Author(s)
      橋岡亜弥, 小橋昌司, 他 7 名
    • Organizer
      メディカルイメージング連合フォーラム
    • Place of Presentation
      沖縄
    • Year and Date
      2011-01-19
    • Related Report
      2012 Final Research Report
  • [Presentation] 新生児頭部MR画像を用いた脳形状正規化法2011

    • Author(s)
      橋岡亜弥, 小橋昌司, 倉本圭, 若田ゆき, 安藤久美子, 石蔵礼一, 石川智基, 廣田省三, 畑豊
    • Organizer
      メディカルイメージング連合フォーラム
    • Place of Presentation
      てんぶす那覇(沖縄)
    • Year and Date
      2011-01-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脳溝特徴分布SDIを用いたFlattening法による脳表位置合わせ2011

    • Author(s)
      山口弘祐, 小橋昌司, 倉本圭, 喜多村祐里, 石川智基, 畑豊
    • Organizer
      メディカルイメージング連合フォーラム
    • Place of Presentation
      てんぶす那覇(沖縄)
    • Year and Date
      2011-01-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] フラクタル次元を用いた小児頭部MR画像からの皮質形成異常度推定法2010

    • Author(s)
      川上順祥, 小橋昌司, 倉本圭, 喜多村祐里, 下野九理子, 石川智基, 谷池雅子, 畑豊
    • Organizer
      メディカルイメージング連合フォーラム
    • Place of Presentation
      てんぶす那覇(沖縄)
    • Year and Date
      2010-01-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脳形状相同モデル化とVoxel-Based Morphometryによる脳形状変形検出の比較2010

    • Author(s)
      山口弘祐, 小橋昌司, 倉本圭, 喜多村祐里, 今脇節朗, 畑豊
    • Organizer
      第20回インテリジェント・システム・シンポジウム
    • Place of Presentation
      東京都立大学(東京)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 小児頭部MR画像における大脳皮質形成異常の画像特徴量の提案2010

    • Author(s)
      川上順祥, 小橋昌司, 倉本圭, 喜多村祐里, 下野九理子, 今脇節朗, 谷池雅子, 畑豊
    • Organizer
      ファジィシステムシンポジウム
    • Place of Presentation
      広島大学(広島)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 粒子法を用いた新生児頭部MR画像からの脳表抽出2010

    • Author(s)
      横道大督, 小橋昌司, 若田ゆき, 石藏礼一, 倉本圭, 今脇節朗, 廣田省三, 畑豊
    • Organizer
      ファジィシステムシンポジウム
    • Place of Presentation
      広島大学(広島)
    • Related Report
      2010 Annual Research Report
  • [Book] 医療用解析技術の現状と動向2012

    • Author(s)
      小橋昌司
    • Related Report
      2012 Final Research Report
  • [Remarks]

    • URL

      http://www.eng.u-hyogo.ac.jp/eecs/eecs14/

    • Related Report
      2012 Final Research Report
  • [Remarks]

    • URL

      http://www.eng.u-hyogo.ac.jp/eecs/kobashi/

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.eng.u-hyogo.ac.jp/eecs/kobashi/index-j.html

    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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