Experience-dependent olfactory information processing for courtship control in Drosophila
Project/Area Number |
22680026
|
Research Category |
Grant-in-Aid for Young Scientists (A)
|
Allocation Type | Single-year Grants |
Research Field |
Neuroscience in general
|
Research Institution | The University of Tokyo (2013) Kyoto University (2010-2012) |
Principal Investigator |
EJIMA Aki 東京大学, 農学生命科学研究科, 講師 (00548571)
|
Project Period (FY) |
2010-04-01 – 2014-03-31
|
Project Status |
Completed (Fiscal Year 2013)
|
Budget Amount *help |
¥25,870,000 (Direct Cost: ¥19,900,000、Indirect Cost: ¥5,970,000)
Fiscal Year 2013: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2012: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2011: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2010: ¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
|
Keywords | 神経情報処理 / 神経科学 / 行動学 / 昆虫 / 生理学 |
Research Abstract |
A male-specific pheromone component, cVA has an inhibitory effect on courtship motivation of the males. However, it was unclear how the male flies distinguish a tiny amount of exogenous cVA from his self-produced cVA and lead to an appropriate behavioral output. In this study, we found that prolonged cVA stimulation allowed the male to ignore constant male odor around for the keen and plastic behavioral responses. With real-time imaging, we found that cVA-responsible sensory neurons were desensitized by constant exposure to cVA in the environment. Pharmacological and genetical screening revealed that inhibitory inputs into the olfactory neurons in the primary olfactory center contributed to the plastic control of odor responses.
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Report
(5 results)
Research Products
(32 results)