• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Smart nanofibers that control cell functions

Research Project

Project/Area Number 22680042
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionNational Institute for Materials Science

Principal Investigator

EBARA Mitsuhiro  独立行政法人物質・材料研究機構, 国際ナノアーキテクトニクス研究拠点, MANA研究者 (10452393)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥24,050,000 (Direct Cost: ¥18,500,000、Indirect Cost: ¥5,550,000)
Fiscal Year 2012: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2011: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2010: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Keywordsナノ材料 / 細胞・組織 / 再生医学 / 生体材料 / 温度応答性高分子 / 電界紡糸法 / 多能性幹細胞 / ナノファイバー / 分化誘導 / 膨潤・収縮 / 光架橋 / 物理架橋
Research Abstract

We prepared smart nanofibers and demonstrate the ability to capture, encapsulate, and release cells or drugs by dynamically transforming the fibrous structure of the nanofibers into hydrogel-like structures by wrapping, swelling, and deswelling processes in response to alternations of external temperature.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (81 results)

All 2013 2012 2011 2010 Other

All Journal Article (29 results) (of which Peer Reviewed: 20 results) Presentation (35 results) (of which Invited: 4 results) Book (12 results) Remarks (1 results) Patent(Industrial Property Rights) (4 results)

  • [Journal Article] A photo-induced nanoparticle separation in microchannels via pH-sensitive surface traps2013

    • Author(s)
      M. Ebara, J. M. Hoffman, A. S. Hoffman, P. S. Stayton, J. J. Lai
    • Journal Title

      Langmuir

      Volume: 29 Issue: 18 Pages: 5388-5393

    • DOI

      10.1021/la400347r

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Shape-Memory Surface with Dynamically Tunable Nano-Geometry Activated by Body Heat2012

    • Author(s)
      Mitsuhiro Ebara, Koichiro Uto, Naokazu Idota, John M.Hoffman, Takao Aoyagi
    • Journal Title

      Advanced Materials

      Volume: 24 Issue: 2 Pages: 273-278

    • DOI

      10.1002/adma.201102181

    • Related Report
      2012 Annual Research Report 2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A smart nanofiber web that captures and release cells2012

    • Author(s)
      Y.-J. Kim, M. Ebara, T. Aoyagi
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 51 Issue: 42 Pages: 10537-10541

    • DOI

      10.1002/anie.201204139

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Photo-switchable control of pH-responsive actuators via pH jump reaction2012

    • Author(s)
      Prapatsorn Techawanitchai, Mitsuhiro Ebara, Naokazu Idota, Taka-Aki Asoh, Akihiko Kikuchi, Takao Aoyagi
    • Journal Title

      Soft Matter

      Volume: 8 Issue: 10 Pages: 2844-2851

    • DOI

      10.1039/c2sm07277g

    • Related Report
      2012 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Light-induced spatial control of pH-jump reaction at smart gel interface2012

    • Author(s)
      Prapatsorn Techawanitchai, Mitsuhiro Ebara, Naokazu Idota, Takao Aoyagi
    • Journal Title

      Colloids and Surfaces B : Biointerfaces

      Volume: (in press) Pages: 53-59

    • DOI

      10.1016/j.colsurfb.2011.09.039

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fabrication of dual-responsive polymer functionalized silica nanoparticles via a simple thiol-ene click chemistry2012

    • Author(s)
      Y. Kotsuchibashi, M. Ebara, T. Aoyagi, R. Narain
    • Journal Title

      Polymer Chemistry

      Volume: 3 Issue: 9 Pages: 2545-2550

    • DOI

      10.1039/c2py20333b

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] A Smart Hydrogel-based Time Bomb Triggers Drug Release Mediated by pH-jump Reaction2012

    • Author(s)
      Prapatsorn Techawanitcha, Naokazu Idota, Mitsuhiro Ebara, Takao Aoyagi
    • Journal Title

      Science and Technology of Advanced Materials

      Volume: 13 Issue: 6 Pages: 64202-64202

    • DOI

      10.1088/1468-6996/13/6/064202

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Temperature-responsive electrospun nanofibers for "on-off" controlled dextran release2012

    • Author(s)
      Y.-J. Kim, M. Ebara, T. Aoyagi
    • Journal Title

      Science and Technology of Advanced Materials

      Volume: 13

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fabrication of FITC-doped silica nanoparticles and study of their ceullar uptake in the presence of lectins2012

    • Author(s)
      Y. Kotsuchibashi, Y. Zhang, M. Ahmed, M. Ebara, T. Aoyagi, R. Narain
    • Journal Title

      Journal of Biomedical Materials Research

      Volume: Part A Issue: 6 Pages: 64207-64207

    • DOI

      10.1088/1468-6996/13/6/064207

    • Related Report
      2012 Annual Research Report 2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Novel temperature-responsive polymer brushes with carbohydrate residues facilitate selective adhesion and collection of hepatocytes2012

    • Author(s)
      N. Idota, M. Ebara, Y. Kotsuchibashi, R. Narain, T. Aoyagi
    • Journal Title

      Science and Technology of Advanced Materials

      Volume: 13

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Temperature-responsive electrospun nanofibers for "on-off" switchable release of dextran2012

    • Author(s)
      Young-Jin Kim
    • Journal Title

      Science and Technology of Advanced Materials

      Volume: 13 Issue: 6 Pages: 64203-64203

    • DOI

      10.1088/1468-6996/13/6/064203

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Substrate stiffness affects skeletal myoblasts differentiation in vitro2012

    • Author(s)
      Romanazzo S
    • Journal Title

      Science and Technology of Advanced Materials

      Volume: 13 Issue: 6 Pages: 64211-64211

    • DOI

      10.1088/1468-6996/13/6/064211

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Novel Temperature-Responsive Polymer Brushes with Carbohydrate Residues Facilitate Selective Adhesion and Collection of Hepatocytes2012

    • Author(s)
      Naokazu Idota, Mitsuhiro Ebara, Yohei Kotsuchibashi, Ravin Narain, Takao Aoyagi
    • Journal Title

      Science and Technology of Advanced Materials

      Volume: 13 Issue: 6 Pages: 64206-64206

    • DOI

      10.1088/1468-6996/13/6/064206

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mesenchymal stem cell adhesion but not plasticity is affected by high substrate stiffness.2012

    • Author(s)
      Tam KV
    • Journal Title

      Science and Technology of Advanced Materials

      Volume: 13 Issue: 6 Pages: 64205-64205

    • DOI

      10.1088/1468-6996/13/6/064205

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Substrate stiffness modulates gene expression and phenotype in neonatal cardiomyocytes in vitro2012

    • Author(s)
      Giancarlo Forte
    • Journal Title

      Tissue Engineering Part A

      Volume: 18 Issue: 17-18 Pages: 1837-1848

    • DOI

      10.1089/ten.tea.2011.0707

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] スマートポリマーを用いた途上国医療への取組み2012

    • Author(s)
      荏原充宏
    • Journal Title

      高分子論文集

      Volume: 69 Pages: 545-554

    • NAID

      10031117795

    • Related Report
      2012 Annual Research Report
  • [Journal Article] スマートバイオマテリアルの応用2012

    • Author(s)
      荏原充宏
    • Journal Title

      ミカルエンジニヤリング

      Volume: 57 Pages: 31-36

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Nanotechnology in Drug Delivery Systems2012

    • Author(s)
      Kohsaku Kawakami
    • Journal Title

      Manipulation of Nanoscale Materials

      Volume: 10 Pages: 242-258

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Supramolecular approaches for drug development2012

    • Author(s)
      Kohsaku Kawakami
    • Journal Title

      Current Medicinal Chemistry

      Volume: 19 Pages: 2388-2398

    • Related Report
      2012 Annual Research Report 2011 Annual Research Report
  • [Journal Article] スマートバイオマアリアルの応用2012

    • Author(s)
      荏原充宏, 青柳隆夫
    • Journal Title

      ケミカルエンジニヤリング

      Volume: 57 Pages: 31-36

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 'スマートゲル表面'特集スマートゲルの最新動向2012

    • Author(s)
      荏原充宏
    • Journal Title

      機能材料

      Volume: 32 Pages: 6-12

    • NAID

      40019194956

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Effect of grafted smart polymer architectures on interaction with hydrophobic molecules in newly developed induction heating chromatography system2011

    • Author(s)
      Hisashi Yagi, Mitsuhiro Ebara, Kazuya Yamamoto, Takao Aoyagi
    • Journal Title

      Materials Science and Engineering C

      Volume: 31 Issue: 8 Pages: 1681-1687

    • DOI

      10.1016/j.msec.2011.07.018

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Surface design with self-heating smart polymers for on-off switchable trap2011

    • Author(s)
      P.Techawanitchai
    • Journal Title

      Science and Technology of Advanced Materials

      Volume: 12 Issue: 4 Pages: 44-609

    • DOI

      10.1088/1468-6996/12/4/044609

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tunable stimuli-responsive self-assembly system that forms and stabilizes nanoparticles by simple mixing and heating/cooling of selected block copolymers2011

    • Author(s)
      Y. Kotsuchibashi, M. Ebara, K. Yamamoto, T. Aoyagi
    • Journal Title

      Polymer Chemistry

      Volume: 2 Issue: 6 Pages: 1362-1367

    • DOI

      10.1039/c1py00004g

    • Related Report
      2011 Annual Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 形状記憶インターフェイスを用いた細胞運命の時間・空間操作2011

    • Author(s)
      荏原充宏
    • Journal Title

      Colloid & Interface Communication

      Volume: 369 Pages: 23-24

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 'On-off' switching of dynamically controllable self-assembly formation of double-responsive block copolymers with tunable LCSTs2010

    • Author(s)
      Youhei Kotsuchibashi, Mitsuhiro Ebara, Kazuya Yamamoto, Takao Aoyagi
    • Journal Title

      Journal of Polymer Science Part A : Polymer Chemistry

      Volume: VOL.48 Pages: 4393-4399

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] スマートゲルのバイオサイエンスへの応用2010

    • Author(s)
      荏原充宏
    • Journal Title

      化学工学

      Volume: VOL.74 Pages: 335-337

    • NAID

      10026871462

    • Related Report
      2010 Annual Research Report
  • [Journal Article] ウィキ・テクノロジー2010

    • Author(s)
      荏原充宏
    • Journal Title

      バイオマテリアル-生体材料

      Volume: VOL.28 Pages: 161-162

    • Related Report
      2010 Annual Research Report
  • [Journal Article] A Smart Hyperthermia Nanofiber with Switchable Drug Release for Inducing Cancer Apoptosis

    • Author(s)
      Y.-J. Kim, M. Ebara, T. Aoyagi
    • Journal Title

      Advanced Functional Materials, in press

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Presentation] Smart nanofibers for "on-off" switchable release of cell/drug2013

    • Author(s)
      Y. Kim, M. Ebara, T. Aoyagi
    • Organizer
      つくば医工連携フォーラム2013 医工連携のHub化~つくば
    • Place of Presentation
      つくば
    • Year and Date
      2013-01-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 自己発熱に応答して薬物を放出するハイパーサーミアナノファイバーの作製2013

    • Author(s)
      荏原充宏, 金榮鎭, 青柳隆夫
    • Organizer
      第62回高分子学会年次大会
    • Place of Presentation
      京都
    • Related Report
      2012 Final Research Report
  • [Presentation] Smart Nanofiber Webs for "On-off" Release of Cells and Drugs2013

    • Author(s)
      M. Ebara, Y. Kim, T. Aoyagi
    • Organizer
      2013 Annual Meeting of the Society For Biomaterials
    • Place of Presentation
      Boston, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] "A Smart Hyperthermia Nanofiber with Controlled Drug Release for Improved Cancer Therapy2013

    • Author(s)
      Y. Kim, M. Ebara, T. Aoyagi
    • Organizer
      2nd International Conference on Biomaterials Science in Tsukuba
    • Place of Presentation
      Japan
    • Related Report
      2012 Final Research Report
  • [Presentation] On-demand Encapsulation and Release of Cells using On-off Switchable Fibrous Hydrogels2013

    • Author(s)
      金榮鎭, 荏原充宏, 青柳隆夫
    • Organizer
      第24回高分子ゲル研究討論会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] smart surfaces with ‘on-off ’ switchable wettability, topography, and stiffness for control of cell functions2013

    • Author(s)
      Mitsuhiro Ebara
    • Organizer
      International Workshop on Functional Polymer Surface and Interface
    • Place of Presentation
      Kanazawa
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] A smart hyperthermia nanofiber with controlled drug release for improved cancer therapy2013

    • Author(s)
      Young-Jin Kim
    • Organizer
      2nd International Conference on Biomaterials Science
    • Place of Presentation
      Tsukuba
    • Related Report
      2012 Annual Research Report
  • [Presentation] Smart nanofibers for “on-off” switchable release of cell/drug / Smart nanofibers for “on-off” switchable release of cell/drug2013

    • Author(s)
      Young-Jin Kim
    • Organizer
      つくば医工連携フォーラム2013
    • Place of Presentation
      つくば
    • Related Report
      2012 Annual Research Report
  • [Presentation] On-demand encapsulation and release of cells using on-off switchable fibrous hydrogels2013

    • Author(s)
      Young-Jin Kim
    • Organizer
      第24回高分子ゲル研究討論会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] "Smart" Shape-Memory Surfaces for Mechano-Structural Control of Cell Functions surface capture/release surface capture/release of cells2012

    • Author(s)
      Mitsuhiro Ebara, Koichiro Uto, Naokazu Idota, John M.Hoffman, Takao Aoyagi
    • Organizer
      SIMS 2012
    • Place of Presentation
      筑波大学(茨城県)
    • Year and Date
      2012-03-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 温度応答性ナノファイバーを用いた薬物の"On-Off" 放出制御2012

    • Author(s)
      金榮鎭, 荏原充宏, 青柳隆夫
    • Organizer
      日本バイオマテリアル学会シンポジウム2012
    • Place of Presentation
      仙台
    • Related Report
      2012 Final Research Report
  • [Presentation] Smart Biomaterials Design for Nano-biotechnology2012

    • Author(s)
      T. Aoyagi, Y. Kim, M. Ebara
    • Organizer
      6th International Workshop on Advanced Materials Science
    • Place of Presentation
      Ha Long City, Vietnam
    • Related Report
      2012 Final Research Report
  • [Presentation] A New Class of Smart Fibrous-Hydrogel that Cell Capture and Release2012

    • Author(s)
      Y. Kim, M. Ebara, T. Aoyagi
    • Organizer
      7th International Symposium on Stimuli-Responsive Materials
    • Place of Presentation
      Santa Rosa, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Thermo-crosslinkable and temperature-responsive fibrous hydrogel via electrospinning for "on-off" controlled dextran release2012

    • Author(s)
      Y. Kim, M. Ebara, T. Aoyagi
    • Place of Presentation
      ゲルワークショップイン名古屋
    • Related Report
      2012 Final Research Report
  • [Presentation] 光架橋点を有するスマートナノファイバーの設計と細胞のキャッチ&リリース2012

    • Author(s)
      荏原充宏, 青柳隆夫
    • Organizer
      第61回高分子討論会
    • Place of Presentation
      名古屋
    • Related Report
      2012 Final Research Report
  • [Presentation] Photo-crosslinkable and Thermo-Responsive Nanofiber Webs for 'On-Off' Switches of Cell Capture/Release2012

    • Author(s)
      Y. Kim, M. Ebara, T. Aoyagi
    • Organizer
      NanoBio Seattle2012
    • Place of Presentation
      Seattle, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Design of photo-crosslinkable and thermo-responsive nanofiber mats for cell manipulations2012

    • Author(s)
      金榮鎭, 荏原充宏, 青柳隆夫
    • Organizer
      第61回高分子学会年次大会
    • Place of Presentation
      横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] “スマート”バイオマテリアルの開発2012

    • Author(s)
      荏原充宏
    • Organizer
      高分子同友会勉強会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 形状記憶表面を用いた細胞の体力測定2012

    • Author(s)
      荏原充宏
    • Organizer
      九州地区高分子若手研究会
    • Place of Presentation
      小倉
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] "Smart" shape-memory surfaces with tunable geometry for on-demand control of cell alignment2012

    • Author(s)
      Mitsuhiro Ebara
    • Organizer
      NanoBio Seattle
    • Place of Presentation
      Seattle
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 光架橋点を有するスマートナノファイバーの設計と細胞のキャッチ&リリース2012

    • Author(s)
      荏原充宏
    • Organizer
      第61回高分子討論会
    • Place of Presentation
      名古屋
    • Related Report
      2012 Annual Research Report
  • [Presentation] 温度応答性ナノファイバーを用いた薬物の“On-Off” 放出制御2012

    • Author(s)
      Young-Jin Kim
    • Organizer
      日本バイオマテリアル学会シンポジウム2012
    • Place of Presentation
      仙台
    • Related Report
      2012 Annual Research Report
  • [Presentation] “On-Off” Switchable Drug Release Platform Using Temperature-Responsive Smart Nanofiber2012

    • Author(s)
      Young-Jin Kim
    • Organizer
      7th International Symposium on Stimuli-Responsive Materials
    • Place of Presentation
      Santa Rosa
    • Related Report
      2012 Annual Research Report
  • [Presentation] 形状記憶を用いた書き換え可能なナノパターンの設計surface capture/release of cells2011

    • Author(s)
      荏原充宏, 宇都甲一郎, 井戸田直和, 青柳隆夫
    • Organizer
      第60回高分子討論会
    • Place of Presentation
      岡山大学(岡山県)
    • Year and Date
      2011-09-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Design of saccharide-bearing smart polymer surfaces and micelles that provide on-off switches to surface capture/release surface capture/release of cells2011

    • Author(s)
      Mitsuhiro Ebara
    • Organizer
      7th National Carbohydrate Symposium
    • Place of Presentation
      Banff(カナダ)(招待講演)
    • Year and Date
      2011-05-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] Design of smart polymer conjugates with peptides and saccharides that provide on-off switches to surface capture/release of cells2011

    • Author(s)
      Mitsuhiro Ebara
    • Organizer
      241^<st> American Chemical Society National Meeting & Exposition
    • Place of Presentation
      Anaheim (USA)
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] Design of smart polymer conjugates with peptides and saccharides that provide on-off switches to surface capture/release of cells2011

    • Author(s)
      Mitsuhiro Ebara
    • Organizer
      241st ACS National Meeting
    • Place of Presentation
      San Diego(米国)
    • Year and Date
      2011-03-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Smart materials with dynamically tunable stiffness for cell separation2011

    • Author(s)
      Koichiro Uto, Mitsuhiro Ebara, Takao Aoyagi
    • Organizer
      Medical Innovation of 21^<st> Century
    • Place of Presentation
      Tokyo (Japan)
    • Year and Date
      2011-01-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] エレクトロスピニング法による"スマート"ファイバーネットの作製2010

    • Author(s)
      前田智広、荏原充宏、青柳隆夫
    • Organizer
      平成22年度繊維学会秋季研究発表会
    • Place of Presentation
      米沢
    • Year and Date
      2010-09-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Design of smart aliphatic polyesters with controlled parallel-channel architectures for nerve repair2010

    • Author(s)
      Mitsuhiro Ebara, Takanari Muroya, Takao Aoyagi
    • Organizer
      Tissue Engineering & Regenerative Medicine International Society 2010 Asia Pacific Meeting
    • Place of Presentation
      Sydney (Australia)
    • Year and Date
      2010-09-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 迅速な"On-off"応答を示す"スマート"ファイバーネットの開発2010

    • Author(s)
      前田智広、荏原充宏、青柳隆夫
    • Organizer
      第59回高分子討論会
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] 新規な細胞培養基材の開発を目指したスマートナノファイバーの創製2010

    • Author(s)
      前田智広、荏原充宏、青柳隆夫
    • Organizer
      第59回高分子学会年次大会
    • Place of Presentation
      横浜
    • Year and Date
      2010-05-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] Pliable semi-crystalline polymer scaffolds with controlled parallel-channelarchitecture for nerve repair2010

    • Author(s)
      Mitsuhiro Ebara, Takao Aoyagi
    • Organizer
      6^<th> Sweden-Japan Workshop on BioNano Technology
    • Place of Presentation
      Mishima (Japan)
    • Year and Date
      2010-05-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] Pliable semi-crystalline polymer scaffolds with controlled parallel-channel architecture for nerve repair2010

    • Author(s)
      Mitsuhiro Ebara, Takanari Muroya, Takao Aoyagi
    • Organizer
      Society for Biomaterials 2010 Annual Meeting & Exposition
    • Place of Presentation
      Seattle (USA)
    • Year and Date
      2010-04-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Switchable surface capture/release systems for cells, biomolecules and analytical beads2010

    • Author(s)
      Mitsuhiro Ebara, Takao Aoyagi, Masayuki Yamato, Teruo Okano
    • Organizer
      International Symposium on Surface Science Aspects of Pharmaceutical Science, Pharmacology, Cosmetics and Bio-technology
    • Place of Presentation
      Danbury (USA)
    • Year and Date
      2010-04-20
    • Related Report
      2010 Annual Research Report
  • [Book] 生分解性高分子' 再生医療叢書2 組織工学2013

    • Author(s)
      荏原充宏, 宇都甲一郎, 青柳隆夫
    • Publisher
      朝倉書店
    • Related Report
      2012 Final Research Report
  • [Book] 免疫反応を制御可能な未来型バイオマテリアルの設計―Immunobioengineering'― Drug Delivery System2013

    • Author(s)
      荏原充宏, 齋藤充弘
    • Publisher
      日本DDS学会
    • Related Report
      2012 Final Research Report
  • [Book] 基材の構造力学的性質による細胞機能の制御' 特集 細胞接着の制御 生体の科学2013

    • Author(s)
      荏原充宏, 宇都甲一郎, 青柳隆夫
    • Related Report
      2012 Final Research Report
  • [Book] Chapter 10 Nanotechnology in Drug Delivery Systems" Manipulation of Nanoscale Materials2012

    • Author(s)
      Kohsaku Kawakami and Mitsuhiro Ebara
    • Related Report
      2012 Final Research Report
  • [Book] スマートバイオマテリアルの応用'― ケミカルエンジニヤリング2012

    • Author(s)
      荏原充宏, 青柳隆夫
    • Publisher
      化学工業社
    • Related Report
      2012 Final Research Report
  • [Book] "Supramolecular approaches for drug development" Current Medicinal Chemistry2012

    • Author(s)
      Kohsaku Kawakami, Mitsuhiro Ebara, Hironori Izawa, Noelia M. Sanchez-Ballester, Jonathan P. Hill, and Katsuhiko Ariga
    • Related Report
      2012 Final Research Report
  • [Book] スマートゲル表面' 特集スマートゲルの最新動向― 機能材料2012

    • Author(s)
      荏原充宏
    • Publisher
      シーエムシー出版
    • Related Report
      2012 Final Research Report
  • [Book] 形状記憶インターフェイスを用いた細胞運命の時間・空間操作' Colloid & Interface Communication2011

    • Author(s)
      荏原充宏
    • Publisher
      日本化学会
    • Related Report
      2012 Final Research Report
  • [Book] "Chapter 9 Carbohydrate-derived Hydrogels and Microgels."Engineered Carbohydrated-based Materials For Biomedical Applications Polymers, Surfaces, Dendrimers, Nanoparticles, and Hydrogels, Edited by R.Narai2011

    • Author(s)
      Mitsuhiro Ebara
    • Total Pages
      18
    • Publisher
      Wiley
    • Related Report
      2010 Annual Research Report
  • [Book] バイオマテリアルの基礎2010

    • Author(s)
      荏原充宏
    • Total Pages
      5
    • Publisher
      日本医学館
    • Related Report
      2010 Annual Research Report
  • [Book] 食品・化粧品・医療分野へのゲルの利用2010

    • Author(s)
      荏原充宏
    • Total Pages
      8
    • Publisher
      シーエムシー出版
    • Related Report
      2010 Annual Research Report
  • [Book] Toward the generation of patient-specific patches for cardiac repair." Stem Cell Reviews and Reports

    • Author(s)
      Giancarlo Forte, Stefania Pagliari, Francesca Pagliari, Mitsuhiro Ebara, Paolo Di Nardo, Takao Aoyagi
    • Related Report
      2012 Final Research Report
  • [Remarks]

    • URL

      http://www.nims.go.jp/bmc/group/smartbiomaterials/

    • Related Report
      2012 Final Research Report
  • [Patent(Industrial Property Rights)] 自己発熱/薬物放出機能性ナノファイバー、その製造方法及び自己発熱/薬物放出機能性不織布2013

    • Inventor(s)
      荏原充宏、青柳隆夫
    • Industrial Property Rights Holder
      (独)物質・材料研究機構
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-003341
    • Filing Date
      2013-01-11
    • Related Report
      2012 Annual Research Report
  • [Patent(Industrial Property Rights)] 分岐型ポリマー、架橋ポリマー、インジェクタブルハイドロゲル、ハイドロゲル形成用キット2012

    • Inventor(s)
      青柳隆夫、荏原充宏、田中信治、菊池明彦、麻生隆彬
    • Industrial Property Rights Holder
      (独)物質・材料研究機構
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2012-108661
    • Filing Date
      2012-05-10
    • Related Report
      2012 Annual Research Report
  • [Patent(Industrial Property Rights)] アジド基又はアルキン基を有するイソプロピルアクリルアミド誘導体およびその重合体2011

    • Inventor(s)
      ジョンホフマン、青柳隆夫、荏原充宏
    • Industrial Property Rights Holder
      物質材料研究機構
    • Industrial Property Number
      2011-067969
    • Filing Date
      2011-03-25
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Patent(Industrial Property Rights)] 被覆HVJ-E及び被覆HVJ-Eの製造方法2011

    • Inventor(s)
      荏原充宏、宇都甲一郎、青柳隆夫、李千萬
    • Industrial Property Rights Holder
      (独)物質・材料研究機構
    • Industrial Property Number
      2011-179272
    • Filing Date
      2011-08-19
    • Related Report
      2011 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi