• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Analysis of molecular mechanisms regulating specific gene expression of sex pheromone receptor genes in the silkmoth

Research Project

Project/Area Number 22688004
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Applied entomology
Research InstitutionThe University of Tokyo

Principal Investigator

SAKURAI Takeshi  東京大学, 先端科学技術研究センター, 特任講師 (20506761)

Project Period (FY) 2010-04-01 – 2013-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥21,320,000 (Direct Cost: ¥16,400,000、Indirect Cost: ¥4,920,000)
Fiscal Year 2012: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2011: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2010: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Keywords昆虫 / 遺伝子 / 発現制御 / 性フェロモン受容体 / カイコガ
Research Abstract

The purpose of this study is to understand molecular mechanisms underlying highly specific gene expression of sex pheromone receptor genes in the silkmoth Bombyx mori. in vivo promoter assay of BmOR1 gene that encodes the sex pheromone receptor for the main pheromone component of the silkmoth, bombykol, indicated that 0.3 kb upstream regulatory sequences of BmOR1 can appropriately induce reporter gene expression in bombykol sensitive olfactory receptor neurons in the male antennae. Analysis of this upstream region revealed the presence of a potential binding site of doublesex protein that is a transcription factor involved in sex determination in the silkmoth. These results provide important information to unrabel the mechanism of sex pheromone receptor gene regulation in the silkmoth.

Report

(4 results)
  • 2013 Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (22 results)

All 2014 2013 2012 2011 Other

All Journal Article (7 results) (of which Peer Reviewed: 5 results) Presentation (12 results) (of which Invited: 4 results) Remarks (3 results)

  • [Journal Article] Molecular and neural mechanisms of sex pheromone reception and processing in the silkmoth Bombyx mori2014

    • Author(s)
      Sakurai T, Namiki S, Kanzaki R
    • Journal Title

      Frontiers in Physiology

      Volume: 5 : Article 125

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pheromone responsiveness threshold depends on temporal integration by antennal lobe projection neurons2013

    • Author(s)
      Tabuchi M, Sakurai T, Mitsuno H, Namiki S, Minegishi R, Shiotsuki T, Uchino K, Sezutsu H, Tamura T, Haupt SS, Nakatani K, Kanzaki R
    • Journal Title

      Proceedings of the National Academy of Sciences USA

      Volume: 110(38) Pages: 15455-15460

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] カイコガにおける性フェロモンの特異的認識メカニズム2013

    • Author(s)
      櫻井健志,田渕理史,神崎亮平
    • Journal Title

      日本味と匂学会誌

      Volume: 20 Pages: 25-31

    • Related Report
      2013 Final Research Report
  • [Journal Article] Pheromone responsiveness threshold depends on temporal integration by antennal lobe projection neurons2013

    • Author(s)
      Tabuchi M, Sakurai T, Mitsuno H, Namiki S, Minegishi R, Shiotsuki T, Uchino K, Sezutsu H, Tamura T, Haupt SS, Nakatani K, Kanzaki R
    • Journal Title

      Proceedings of the National Academy of Sciences of USA

      Volume: 110(38) Issue: 38 Pages: 15455-60

    • DOI

      10.1073/pnas.1313707110

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] カイコガにおける性フェロモンの特異的認識機構2013

    • Author(s)
      櫻井健志,田渕理史,神崎亮平
    • Journal Title

      日本味と匂学会誌

      Volume: 20 Pages: 41-47

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Sex-linked transcription factor involved in a shift of sex-pheromone preference in the silkmoth Bombyx mori2011

    • Author(s)
      Fujii T, Fujii T, Namiki S, Abe H, Sakurai T, Ohnuma A, Kanzaki R, Katsuma S, Ishikawa Y, Shimada T
    • Journal Title

      Proceedings of the National Academy of Sciences USA

      Volume: 108 Pages: 18038-18043

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sex-linked transcription factor involved in a shift of sex-pheromone preference in the silkmoth Bombyx mori2011

    • Author(s)
      Fujii Tsuguru
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 108 Issue: 44 Pages: 18038-18043

    • DOI

      10.1073/pnas.1107282108

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] 性フェロモン受容体遺伝子ノックアウトカイコガの生理・行動学的解析2014

    • Author(s)
      櫻井健志,光野秀文,三上晃久,内野恵郎,田渕理史,Zhang Feng,瀬筒秀樹,神崎亮平
    • Organizer
      第58回日本応用動物昆虫学会
    • Place of Presentation
      高知,高知大学
    • Related Report
      2013 Final Research Report
  • [Presentation] A single sex pheromone receptor mediates physiological and behavioral responses to a sex pheromone in the silkmoth Bombyx mori2013

    • Author(s)
      Sakurai T, Mitsuno H, Uchino K, Tabuchi M, Zhang F, Sezutsu H, Kanzaki R
    • Organizer
      The 13th European Symposium for Insect Taste and Olfaction
    • Place of Presentation
      Villasimius, Italy
    • Related Report
      2013 Final Research Report 2012 Annual Research Report
  • [Presentation] 性フェロモン受容体遺伝子ノックアウトカイコガの生理・行動学的解析2013

    • Author(s)
      櫻井健志,光野秀文,内野恵郎,田渕理史,Zhang Feng,瀬筒秀樹,神崎亮平
    • Organizer
      日本味と匂学会第47回大会
    • Place of Presentation
      仙台,仙台市民会館
    • Related Report
      2013 Final Research Report
  • [Presentation] 性フェロモン受容体遺伝子ノックアウトカイコガの生理・行動学的解析2013

    • Author(s)
      櫻井健志,光野秀文,内野恵郎,田渕理史,Zhang Feng,瀬筒秀樹,神崎亮平
    • Organizer
      日本味と匂学会第47回大会
    • Place of Presentation
      仙台,仙台市民会館
    • Related Report
      2012 Annual Research Report
  • [Presentation] オス蛾の性フェロモン選択性と高感度性の分子・神経基盤2012

    • Author(s)
      櫻井健志,田渕理史,神崎亮平
    • Organizer
      第46回日本味と匂学会大会
    • Place of Presentation
      大阪大学コンベンションセンター,大阪
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] Specificity and sensitivity of sex pheromone perception in the silkmoth Bombyx mori2012

    • Author(s)
      Sakurai T, Tabuchi M, Kanzaki R
    • Organizer
      The 12th International Society of Developmental & Comparative Immunology, JADCI sponsored special symposium "Recognition Mechanisms -Current topics in comparative biology-"
    • Place of Presentation
      Hilton Fukuoka Seahawk, Fukuoka, Japan
    • Related Report
      2013 Final Research Report
    • Invited
  • [Presentation] オス蛾の性フェロモン選択性と高感度性の分子・神経基盤2012

    • Author(s)
      櫻井健志,田渕理史,神崎亮平
    • Organizer
      第56回日本応用動物昆虫学会大会
    • Place of Presentation
      奈良,近畿大学
    • Related Report
      2013 Final Research Report
  • [Presentation] Specificity and sensitivity of sex pheromone perception in the silkmoth Bombyx mori2012

    • Author(s)
      Sakurai T, Tabuchi M, Kanzaki R
    • Organizer
      The 12th International Society of Developmental & Comparative Immunology, JADCI sponsored special symposium
    • Place of Presentation
      Hilton Fukuoka Seahawk, Fukuoka, Japan
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] オス蛾の性フェロモン選択性と高感度性の分子・神経基盤2012

    • Author(s)
      櫻井健志,田渕理史,神崎亮平
    • Organizer
      第46回日本味と匂学会大会
    • Place of Presentation
      大阪大学コンベンションセンター,大阪
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] オス蛾の性フェロモン選択性と高感度性の分子・神経基盤2012

    • Author(s)
      櫻井 健志
    • Organizer
      第56回日本応用動物昆虫学会大会
    • Place of Presentation
      近畿大学農学部奈良キャンパス
    • Related Report
      2011 Annual Research Report
  • [Presentation] フェロモン源定位行動発現の匂い特異性を決定する分子・神経基盤2011

    • Author(s)
      櫻 井健志, 光野秀文, Haupt Stephan Shuichi,内野恵郎,横張文男,小林功,西岡孝明,瀬筒秀樹,田村俊樹,神崎亮平
    • Organizer
      第55回日本応用動物昆虫学会大会
    • Place of Presentation
      九州
    • Year and Date
      2011-03-29
    • Related Report
      2013 Final Research Report
  • [Presentation] フェロモン源定位行動発現の匂い特異性を決定する分子・神経基盤2011

    • Author(s)
      櫻井健志
    • Organizer
      第55回日本応用動物昆虫学会
    • Place of Presentation
      九州大学,福岡
    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.brain.rcast.u-tokyo.ac.jp/

    • Related Report
      2013 Final Research Report
  • [Remarks] 東京大学先端科学技術研究センター 生命知能システム分野 神崎・高橋研究室

    • URL

      http://www.brain.rcast.u-tokyo.ac.jp/

    • Related Report
      2011 Annual Research Report
  • [Remarks]

    • URL

      http://www.brain.rcast.u-tokyo.ac.jp/

    • Related Report
      2010 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi