Understanding the mechanisms that generate sex differences in the teleost brain
| Project/Area Number |
22688015
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
General fisheries
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| Research Institution | The University of Tokyo |
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Principal Investigator |
OKUBO Kataaki 東京大学, 大学院・農学生命科学研究科, 准教授 (10370131)
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥19,760,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥4,560,000)
Fiscal Year 2012: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2011: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2010: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
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| Keywords | 魚類 / 脳 / メダカ / 性差 |
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| Research Abstract |
Teleost fish exhibit sex differences in a variety of behavioral and endocrine patterns. However, virtually nothing is known about what brain mechanisms underlie these sex differences. The present study has revealed that a steroidogenic enzyme and sex steroid receptors are female-specifically or female-preferentially expressed in several regions of the medaka brain, resulting from the action of estrogen derived from the ovary. These systems within the brain may be relevant to sex differences in some behavioral and/or physiological traits.
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Report
(4 results)
Research Products
(27 results)
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[Journal Article] Sex differences in aromatase gene expression in the medaka brain2011
Author(s)
Okubo, K., Takeuchi, A., Chaube, R., Paul-Prasanth, B., Kanda, S., Oka, Y., and Nagahama, Y.
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Journal Title
Journal of Neuroendocrinology
Volume: 23
Issue: 5
Pages: 412-423
DOI
Related Report
Peer Reviewed
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