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Genome tailor-made evaluation of gout risk by molecular epidemiologic analysis toward early prevention of gout

Research Project

Project/Area Number 22689021
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Hygiene
Research InstitutionNational Defense Medical College

Principal Investigator

MATSUO Hirotaka  防衛医科大学校, 医学教育部医学科専門課程, 講師 (00528292)

Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥23,790,000 (Direct Cost: ¥18,300,000、Indirect Cost: ¥5,490,000)
Fiscal Year 2012: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2011: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2010: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
Keywords分子遺伝疫学 / 予防医学 / 個人差医療 / 尿酸 / 遺伝統計学 / 個人差医療に基づく予防医学
Research Abstract

In this study, we collected genome samples and clinical information from gout/hyperuricemia cases and controls. As a case only study, we genotyped 644 hyperuricemia patients for ABCG2 dysfunctional variants, which revealed that “decrease of extra-renal urate excretion is a common cause of hyperuricemia”(Nature Communications, 2012). In addition, a genome wide association study of gout is also ongoing with the support of the Grant-in-Aid for Scientific Research on Innovative Areas ”Genome Sciences”. So far, we obtained several positive data by preliminary analysis, and we convince ourselves that we will report on the important gout susceptible genes soon.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (150 results)

All 2013 2012 2011 2010 Other

All Journal Article (30 results) (of which Peer Reviewed: 14 results) Presentation (96 results) Book (23 results) Remarks (1 results)

  • [Journal Article] Decreased extra-renal urate excretion is a common cause of hyperuricemia2012

    • Author(s)
      Ichida K, Matsuo H
    • Journal Title

      Nat Commun

      Volume: Vol.3 Pages: 764-764

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] L:-Leucine induces growth arrest and persistent ERK activation in glioma cells2012

    • Author(s)
      Takeuchi S
    • Journal Title

      Amino Acids

      Volume: Vol.43、No.2 Pages: 717-724

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Decreased extra-renal urate excretion is a common cause of hyperuricemia2012

    • Author(s)
      Kimiyoshi Ichida, Hirotaka Matsuo, Tappei Takada, et al (Hiroshi Suzuki)
    • Journal Title

      Nature Communication

      Volume: 3 Issue: 1 Pages: 1-7

    • DOI

      10.1038/ncomms1756

    • URL

      https://localhost/en/publications/719645f5-4ec4-4f6b-a2a8-f58d7f666857

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 代謝 臨床分野での進歩 腎性低尿酸血症の遺伝学2012

    • Author(s)
      松尾洋孝
    • Journal Title

      Annual Review糖尿病・代謝・内分泌 2012

      Volume: - Pages: 145-154

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 【臨床医のための高尿酸血症・痛風のABC】 その他 痛風の遺伝素因を教えてください2012

    • Author(s)
      松尾洋孝
    • Journal Title

      高尿酸血症と痛風

      Volume: 20 Pages: 84-86

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 【腎疾患治療マニュアル2012-13】 尿細管疾患 尿細管機能異常症 腎性低尿酸血症2012

    • Author(s)
      中山昌喜
    • Journal Title

      腎と透析

      Volume: - Pages: 370-373

    • Related Report
      2012 Annual Research Report
  • [Journal Article] テーマ:A.診断8.低尿酸血症の頻度(人種差も含め), 原因, 分類を教えてください2012

    • Author(s)
      千葉俊周
    • Journal Title

      腎と透析

      Volume: - Pages: 301-304

    • Related Report
      2012 Annual Research Report
  • [Journal Article] 尿酸動態の支配要因としての尿酸トランスポーター2012

    • Author(s)
      松尾洋孝
    • Journal Title

      細胞工学

      Volume: 31 Pages: 553-557

    • Related Report
      2012 Annual Research Report
  • [Journal Article] Decreased extra-renal urate excretion is a common cause of hyperuricemia2012

    • Author(s)
      K.Ichida, H.Matsuo. T.Takada, A.Nakayama, K.Murakami, T.Shimizu, Y.Yamanashi, H.Kasuga, H.Nakashima, T.Nakamura, Y.Takada, Y.Kawamura, H.Inoue, C.Okada, Y.Utsumi, Y.Ikebuchi, K.Ito, M.Nakamura, Y.Shinohara, M.Hosoyamada, Y.Sakurai, N.Shinomiya, T.Hosoya, H.Suzuki
    • Journal Title

      Nat Commun

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 代謝臨床分野での進歩腎性低尿酸血症の遺伝学2012

    • Author(s)
      松尾洋孝, 四ノ宮成祥
    • Journal Title

      Annual Review糖尿病・代謝・内分泌2012

      Pages: 145-154

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 【臨床医のための高尿酸血症・痛風のABC】その他痛風の遺伝素因を教えてください2012

    • Author(s)
      松尾洋孝
    • Journal Title

      高尿酸血症と痛風

      Pages: 84-86

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 腎性低尿酸血症2012

    • Author(s)
      中山昌喜, 松尾洋孝, 市田公美, 四ノ宮成祥
    • Journal Title

      腎と透析

      Volume: (印刷中)

    • NAID

      40021012150

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Kawamura Y, Matsuo H他 Pathogenic GLUT9 Mutations Causing Renal Hypouricemia Type 2 (RHUC2)2011

    • Author(s)
      Kawamura Y, Matsuo H
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: Vol.30、No.12 Pages: 1105-1111

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ABCG2 is a high-capacity urate transporter and its genetic impairment increases serum uric acid levels in humans2011

    • Author(s)
      Nakayama A, Matsuo H
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: Vol.30、No.12 Pages: 1091-1097

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Identification of ABCG2 dysfunction as a major factor contributing to gout2011

    • Author(s)
      Matsuo H
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: Vol.30、No.12 Pages: 1098-1104

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ABCG2/BCRP dysfunction as a major cause of gout2011

    • Author(s)
      Matsuo H
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: Vol.30、No.12 Pages: 1117-1128

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Significant association of serum uric acid levels with SLC2A9 rs11722228 among a Japanese population2011

    • Author(s)
      Hamajima N
    • Journal Title

      Mol Genet Metab

      Volume: Vol.103、No.4 Pages: 378-382

    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] ABCG2/BCRP dysfunction as a major cause of gout2011

    • Author(s)
      H.Matsuo, T.Takada, K.Ichida, T.Nakamura, A.Nakayama, H.Suzuki, T.Hosoya, N.Shinomiya
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: 30 Issue: 12 Pages: 1117-1128

    • DOI

      10.1080/15257770.2011.633954

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ABCG2 is a high-capacity urate transporter and its genetic impairment increases serum uric acid levels in humans2011

    • Author(s)
      A.Nakayama, H.Matsuo. T.Takada, K.Ichida, T.Nakamura, Y.Ikebuchi, K.Ito, T.Hosoya, Y.Kanai, H.Suzuki, N.Shinomiya
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: 30 Issue: 12 Pages: 1091-1097

    • DOI

      10.1080/15257770.2011.633953

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of ABCG2 dysfunction as a major factor contributing to gout2011

    • Author(s)
      H.Matsuo, T.Takada, K.Ichida, T.Nakamura, A.Nakayama, Y.Takada, C.Okada, Y.Sakurai, T.Hosoya, Y.Kanai, H.Suzuki, N.Shinomiya
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: 30 Issue: 12 Pages: 1098-1104

    • DOI

      10.1080/15257770.2011.627902

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Pathogenic GLUT9 mutations causing renal hypouricemia type 2 (RHUC2)2011

    • Author(s)
      Y.Kawamura, H.Matsuo. T.Chiba, S.Nagamori, A.Nakayama, H.Inoue, Y.Utsumi, T.Oda, J.Nishiyama, Y.Kanai, N.Shinomiya
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids

      Volume: 30 Issue: 12 Pages: 1105-1111

    • DOI

      10.1080/15257770.2011.623685

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 第7章尿酸のトランスポーター2011

    • Author(s)
      松尾洋孝
    • Journal Title

      栄養・食品機能とトランスポーター

      Pages: 145-166

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 【尿酸】高尿酸血症と腎輸送体2011

    • Author(s)
      松尾洋孝
    • Journal Title

      腎臓

      Volume: 34 Pages: 16-22

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 痛風・高尿酸血症の原因遺伝子(ABCG2)2011

    • Author(s)
      高田雄三, 松尾洋孝
    • Journal Title

      Medical Technology

      Volume: 39 Pages: 884-886

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 尿酸排出トランスポーターABCG2/BCRPと痛風発症リスク2011

    • Author(s)
      高田龍平, 松尾洋孝
    • Journal Title

      生化学

      Volume: 83 Pages: 1131-1135

    • NAID

      10030345996

    • Related Report
      2011 Annual Research Report
  • [Journal Article] 痛風・高尿酸血症の原因遺伝子(ABCG2)2011

    • Author(s)
      高田雄三, 松尾洋孝
    • Journal Title

      臨床検査学雑誌 Medical Technology

      Volume: (印刷中)

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 痛風の病因遺伝子2010

    • Author(s)
      松尾洋孝
    • Journal Title

      痛風と核酸代謝

      Volume: 34 Pages: 159-169

    • NAID

      10027722166

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Transient degradation of myelin basic protein in the rat hippocampus following acute carbon monoxide poisoning2010

    • Author(s)
      Watanabe S, Matsuo H, Kobayashi Y, Satoh Y, Fujita M, Nakayama A, Aizawa Y, Shinomiya N, Suzuki S
    • Journal Title

      Neurosci Res

      Volume: 68 Pages: 232-240

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 痛風の遺伝子2010

    • Author(s)
      中山昌喜, 松尾洋孝, 四ノ宮成祥
    • Journal Title

      リウマチ科

      Volume: 44 Pages: 689-694

    • Related Report
      2010 Annual Research Report
  • [Journal Article] 痛風診療最前線 1.遺伝要因2010

    • Author(s)
      中山昌喜, 松尾洋孝, 四ノ宮成祥
    • Journal Title

      内科系総合雑誌 Modern Physician

      Volume: 30 Pages: 1385-1388

    • Related Report
      2010 Annual Research Report
  • [Presentation] 尿酸の腸管排泄低下は高尿酸血症の主要な新規機序である2013

    • Author(s)
      市田公美、松尾洋孝
    • Organizer
      日本消化器学会第99回総会
    • Place of Presentation
      鹿児島
    • Related Report
      2012 Final Research Report
  • [Presentation] Decreased urate excretion from intestine is a common cause of hyperuricemia. 腸管における尿酸排泄の低下は高尿酸血症の新規機序である2013

    • Author(s)
      松尾洋孝
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京(学会賞受賞)
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2の機能低下による腎外の尿酸排泄低下:高尿酸血症の症例解析と動物モデル解析2013

    • Author(s)
      松尾洋孝
    • Organizer
      第46回日本痛風・核酸代謝学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 腎性低尿酸血症の実態把握調査について(第1報)2013

    • Author(s)
      中山昌喜、松尾洋孝
    • Organizer
      第46回日本痛風・核酸代謝学会総会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2遺伝子タイピングに基づく高尿酸血症における新規病型分類の提唱2013

    • Author(s)
      高田雄三、松尾洋孝
    • Organizer
      第23回生物試料分析科学学会年次集会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風病因遺伝子ABCG2の解析による高尿酸血症の新規病態の解明2013

    • Author(s)
      松尾洋孝
    • Organizer
      第23回日本疫学会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風病因遺伝子ABCG2の変異が血清尿酸値におよぼす影響2013

    • Author(s)
      中山昌喜、松尾洋孝、高田雄三、中島宏、佐藤弘樹、中村好宏、森厚嘉、内藤真理子、菱田朝陽、若井建志、清水聖子、及川雄二、丹羽和紀、櫻井裕、市田公美、浜島信之、四ノ宮成祥
    • Organizer
      第23回日本疫学会
    • Place of Presentation
      大阪
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風遺伝子ABCG2の迅速診断法の確立2012

    • Author(s)
      佐々木裕明, 高田雄三, 松尾洋孝
    • Organizer
      第57回防衛衛生学会
    • Place of Presentation
      東京
    • Year and Date
      2012-02-02
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] 不随意運動モデルハムスターdt^<sz>における候補遺伝子ME-1の解析2012

    • Author(s)
      寺重翔、松尾洋孝、岡田千沙、濱田剛、小懸開、加藤八重、尾上裕行、海田賢一、小林靖、鎌倉恵子、四ノ宮成祥
    • Organizer
      第57回防衛衛生学会
    • Place of Presentation
      東京
    • Year and Date
      2012-02-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 全自動SNPタイピング装置を利用した痛風の遺伝子タイピング2012

    • Author(s)
      高田雄三、松尾洋孝
    • Organizer
      日本DNA多型学会第21回学術集会
    • Place of Presentation
      京都
    • Related Report
      2012 Final Research Report
  • [Presentation] Common dysfunctional variants of ABCG2 decrease extra-renal urate excretion and cause hyperuricemia2012

    • Author(s)
      Matsuo H
    • Organizer
      2012 American Society of Human Genetics 62nd Annual Meeting
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2遺伝子変異に基づく高尿酸血症の病態解明と新規病型分類2012

    • Author(s)
      松尾洋孝
    • Organizer
      日本人類遺伝学会第57回大会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2機能低下による「腎外排泄低下型」高尿酸血症2012

    • Author(s)
      中山昌喜、松尾洋孝
    • Organizer
      日本薬理学会関東部会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] Genetic analysis of paroxysmal dystonic choreoathetosis (PDC/PNKD); Patient and hamster model study2012

    • Author(s)
      Matsuo H
    • Organizer
      the 16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland
    • Related Report
      2012 Final Research Report
  • [Presentation] 高尿酸血症の新たな発症機序の解明: ABCG2の機能低下による腸管からの尿酸排泄低下2012

    • Author(s)
      内海由貴、松尾洋孝
    • Organizer
      第7回日本トランスポーター研究会年会
    • Place of Presentation
      京都
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2/BCRPによる腸管への尿酸排泄の低下は腎外排泄低下型高尿酸血症を引き起こす2012

    • Author(s)
      高田龍平、市田公美、松尾洋孝
    • Organizer
      日本薬剤学会第25年会
    • Place of Presentation
      神戸
    • Related Report
      2012 Final Research Report
  • [Presentation] Influence of ABCG2 dysfunction on uric acid excretion pathways2012

    • Author(s)
      Kimiyoshi Ichida, Hirotaka Matsuo
    • Organizer
      European Human Genetics Conference 2012
    • Place of Presentation
      Nurnberg, Germany
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風リスク遺伝子検査法の確立2012

    • Author(s)
      高田雄三, 松尾洋孝
    • Organizer
      第22回生物試料分析科学会年次学術集会
    • Place of Presentation
      福岡
    • Related Report
      2012 Final Research Report
  • [Presentation] Genotyping ABCG2 to estimate gout risk- for practical use in the clinical setting2012

    • Author(s)
      Matsuo H
    • Organizer
      4th Federation of European Biochemical Societies (FEBS) special meeting on ATP-Binding Cassette (ABC) Proteins (ABC2012)
    • Place of Presentation
      Innsbruck, Austria
    • Related Report
      2012 Final Research Report
  • [Presentation] 実用化に向けた痛風リスク遺伝子タイピング2012

    • Author(s)
      高田雄三, 松尾洋孝
    • Organizer
      第9回臨床福祉研究学術集会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] 生薬からの尿酸トランスポーターURAT1阻害物質の探索2012

    • Author(s)
      中山昌喜, 松尾洋孝
    • Organizer
      日本生薬学会第59回年会
    • Place of Presentation
      千葉
    • Related Report
      2012 Annual Research Report 2012 Final Research Report
  • [Presentation] 痛風病因遺伝子ABCG2の変異と血清尿酸値との関連2012

    • Author(s)
      中山昌喜, 松尾洋孝
    • Organizer
      第22回日本疫学会学術総会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 高尿酸血症の新たな発症機序の解明:ABCG2の機能低下による腸管からの尿酸排泄低下2012

    • Author(s)
      内海由貴
    • Organizer
      第7回日本トランスポーター研究会年会
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
  • [Presentation] Genetic analysis of paroxysmal dystonic choreoathetosis (PDC/PNKD); Patient and hamster model study2012

    • Author(s)
      Matsuo H
    • Organizer
      the 16th International Congress of Parkinson's Disease and Movement Disorders
    • Place of Presentation
      Dublin, Ireland,
    • Related Report
      2012 Annual Research Report
  • [Presentation] ABCG2遺伝子変異に基づく高尿酸血症の病態解明と新規病型分類.2012

    • Author(s)
      松尾洋孝
    • Organizer
      日本人類遺伝学会第57回大会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] ABCG2機能低下による「腎外排泄低下型」高尿酸血症.2012

    • Author(s)
      中山昌喜
    • Organizer
      日本薬理学会関東部会
    • Place of Presentation
      東京
    • Related Report
      2012 Annual Research Report
  • [Presentation] Common dysfunctional variants of ABCG2 decrease extra-renal urate excretion and cause hyperuricemia2012

    • Author(s)
      Matsuo H
    • Organizer
      American Society of Human Genetics 62nd Annual Meeting
    • Place of Presentation
      San Francisco, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] 全自動SNPタイピング装置を利用した痛風の遺伝子タイピング.2012

    • Author(s)
      高田雄三
    • Organizer
      日本DNA多型学会第21回学術集会
    • Place of Presentation
      京都
    • Related Report
      2012 Annual Research Report
  • [Presentation] ABCG2/BCRPによる腸管への尿酸排泄の低下は腎外排泄低下型高尿酸血症を引き起こす.2012

    • Author(s)
      高田龍平
    • Organizer
      日本薬剤学会第25年会
    • Place of Presentation
      神戸
    • Related Report
      2012 Annual Research Report
  • [Presentation] 蛇床子の尿酸トランスポーターURAT1阻害作用とその活性成分.2012

    • Author(s)
      田代雄祐
    • Organizer
      第42回日本東洋医学会東海支部学術総会
    • Place of Presentation
      名古屋
    • Related Report
      2012 Annual Research Report
  • [Presentation] ABCG2/BCRPによる腸管への尿酸排泄の低下は腎外排泄低下型高尿酸血症をもたらす.2012

    • Author(s)
      高田龍平
    • Organizer
      第6回トランスポーター研究会九州部会
    • Place of Presentation
      福岡
    • Related Report
      2012 Annual Research Report
  • [Presentation] ABCG2/BCRPによる腸管への尿酸排泄の低下は腎外排泄低下型高尿酸血症の原因となる.2012

    • Author(s)
      高田龍平
    • Organizer
      医療薬学フォーラム2012/第20回クリニカルファーマシーシンポジウム
    • Place of Presentation
      福岡
    • Related Report
      2012 Annual Research Report
  • [Presentation] 痛風病因遺伝子ABCG2の変異と血清尿酸値との関連2012

    • Author(s)
      中山昌喜、松尾洋孝、及川雄二、高田雄三、中島宏、中村好宏、井上寛規、森厚嘉、内藤真理子、菱田朝陽、若井建志、丹羽和紀、櫻井裕、浜島信之、四ノ宮成祥
    • Organizer
      第22回日本疫学会
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report
  • [Presentation] 大規模健診サンプルを用いたABCG2遺伝子多型と血清尿酸値との関連解析2012

    • Author(s)
      中山昌喜、松尾洋孝、市田公美、高田龍平、中材好宏、井上寛規、岡田千沙、浜島信之、四ノ宮成祥
    • Organizer
      第45回日本痛風・核酸代謝学会総会
    • Place of Presentation
      奈良
    • Related Report
      2011 Annual Research Report
  • [Presentation] Changes in uric acid levels with dysfunctional ABCG2 and novel pathophysiological model of hyperuricemia2012

    • Author(s)
      Akiyoshi Nakayama, Hirotaka Matsuo, Kimiyoshi Ichida, Tappei Takada, Yuzo Takada, Hiroshi Nakashima, Takahiro Nakamura, Yutaka Sakurai, Nobuyuki Hamajima, Hiroshi Suzuki, Nariyoshi Shinomiya
    • Organizer
      4th FEBS special Meeting (ABC2012)
    • Place of Presentation
      Innsbruck, Austria
    • Related Report
      2011 Annual Research Report
  • [Presentation] Genotyping ABCG2 to estimate gout risk-for practical use in the clinical setting2012

    • Author(s)
      Hirotaka Matsuo, Yuzo Takada, Akiyoshi Nakayama, Yoshitaka Utsumi, Nariyoshi Shinomiya
    • Organizer
      4th FEBS Special Meeting (ABC2012)
    • Place of Presentation
      Innsbruck, Austria
    • Related Report
      2011 Annual Research Report
  • [Presentation] 不随意運動モデルハムスターdt^<sz>における病因分子の探索2012

    • Author(s)
      内海由貴、松尾洋孝、岡田千沙、Svenja E.Sander、Angelika Richter、中山昌喜、加藤八重、寺重翔、鎌倉恵子、四ノ宮成祥
    • Organizer
      第89回日本生理学会大会
    • Place of Presentation
      松本
    • Related Report
      2011 Annual Research Report
  • [Presentation] 痛風・高尿酸血症の主要病因遺伝子の同定と病態の解明2011

    • Author(s)
      松尾洋孝
    • Organizer
      東京大学医学部附属病院腎臓・内分泌内科リサーチカンファランス
    • Place of Presentation
      東京
    • Year and Date
      2011-11-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風・高尿酸血症の主要病因遺伝子の同定と病態の解明2011

    • Author(s)
      松尾洋孝
    • Organizer
      東京大学医学部附属病院腎臓・内分泌内科リサーチカンファランス
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-11-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] 細胞培養系を用いた一酸化炭素中毒神経障害メカニズム解析の試み2011

    • Author(s)
      四ノ宮成祥, 中山昌喜, 松尾洋孝, 守本祐司, 藤田真敬, 立花正一, 鈴木信哉
    • Organizer
      第8回日本臨床高気圧酸素・潜水医学会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] 尿酸排泄トランスポーターABCG2/BCRP:痛風の主要病因と個人裁量の展望2011

    • Author(s)
      松尾洋孝
    • Organizer
      金沢大学薬学シンポジウム2011 ?創薬動態フォーラムin金沢
    • Place of Presentation
      金沢
    • Year and Date
      2011-07-29
    • Related Report
      2012 Final Research Report
  • [Presentation] 尿酸排泄トランスポーターABCG2/BCRP:痛風の主要病因と個人差医療の展望2011

    • Author(s)
      松尾洋孝
    • Organizer
      金沢大学薬学シンポジウム2011
    • Place of Presentation
      金沢(招待講演)
    • Year and Date
      2011-07-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] 痛風の主要病因遺伝子ABCG2/BCRPの解明とオーダーメイド医療の可能性2011

    • Author(s)
      松尾洋孝
    • Organizer
      流山市医師会学術講演会
    • Place of Presentation
      流山
    • Year and Date
      2011-06-15
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風の主要病因遺伝子ABCG2/BCRPの解明とオーダーメイド医療の可能性2011

    • Author(s)
      松尾洋孝
    • Organizer
      流山市医師会学術講演会
    • Place of Presentation
      流山(招待講演)
    • Year and Date
      2011-06-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] 痛風・高尿酸血症の新規診断・治療ターゲット:主要病因遺伝子ABCG2/BCRP2011

    • Author(s)
      松尾洋孝
    • Organizer
      第2回福岡核酸代謝研究会
    • Place of Presentation
      福岡(招待講演)
    • Year and Date
      2011-06-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] 健康診断受検者における尿酸排泄輸送体ABCG2の機能低下の頻度解析2011

    • Author(s)
      内海由貴, 松尾洋孝, 河村優輔, 中山昌喜, 井上寛規, 高田雄三, 西山純一郎, 櫻井裕, 四ノ宮成祥
    • Organizer
      第56回防衛衛生学会
    • Place of Presentation
      東京
    • Year and Date
      2011-02-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] High Resolution Melting法によるABCG2遺伝子のSNPタイピング2011

    • Author(s)
      高田雄三, 松尾洋孝
    • Organizer
      日本DNA多型学会 第20回学術集会
    • Place of Presentation
      横浜
    • Related Report
      2012 Final Research Report
  • [Presentation] Gout is caused by common dysfunctional variants of ABCG2/BCRP2011

    • Author(s)
      Matsuo H
    • Organizer
      BioMedical Transporters 2011
    • Place of Presentation
      Grindelwald, Switzerland
    • Related Report
      2012 Final Research Report 2011 Annual Research Report
  • [Presentation] ABCG2 is a major causative gene for gout2011

    • Author(s)
      Matsuo H
    • Organizer
      The 1st Symposium of Asia Pacific League of Associations for Rheumatology (APLAR)
    • Place of Presentation
      Taipei, Taiwan(Young Investigator Award受賞)
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2/BCRP dysfunction as a major cause for gout2011

    • Author(s)
      Matsuo H
    • Organizer
      14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP11
    • Place of Presentation
      Tokyo
    • Related Report
      2012 Final Research Report
  • [Presentation] Pathogenic GLUT9 mutations causing renal hypouricemia type 2 (RHUC2)2011

    • Author(s)
      Kawamura Y, Matsuo H
    • Organizer
      14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP11
    • Place of Presentation
      Tokyo
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2 is a high-capacity urate transporter and its genetic impairment increase serum uric acid levels in humans2011

    • Author(s)
      Nakayama A, Matsuo H
    • Organizer
      14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP11
    • Place of Presentation
      Tokyo(国際学会賞・受賞)
    • Related Report
      2012 Final Research Report
  • [Presentation] Identification of ABCG2 dysfunction as a major cause for gout2011

    • Author(s)
      Matsuo H
    • Organizer
      14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP11
    • Place of Presentation
      Tokyo
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2 is a major causative gene for gout2011

    • Author(s)
      H.Matsuo, T.Takada, K.Ichida, T.Nakamura, A.Nakayama, T.Chiba, Y.Takada, H.Inoue, Y.Kawamura, Y.Utsumi, K.Suzuki, S.Watanabe, Y.Sakurai, T.Hosoya, H.Suzuki, N.Hamajima, N.Shinomiya
    • Organizer
      the 1st Symposium of Asia Pacific League of Associations for Rheumatology
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2011 Annual Research Report
  • [Presentation] 痛風リスク遺伝子の迅速SNPタイピング2011

    • Author(s)
      高田雄三、松尾洋孝、丹羽和紀、四ノ宮成祥
    • Organizer
      第60回日本医学検査学会
    • Place of Presentation
      東京
    • Related Report
      2011 Annual Research Report
  • [Presentation] 発作性神経疾患をきたす膜輸送体病:大家系症例の臨床遺伝学的解析と疾患モデル動物の評価2011

    • Author(s)
      河村優輔、松尾洋孝、岡田千沙、濱田剛、中山昌喜、内海由貴、尾上裕行、海田賢一、守本祐司、小林靖、鎌倉恵子、四ノ宮成祥
    • Organizer
      第6回トランスポーター研究会
    • Place of Presentation
      仙台
    • Related Report
      2011 Annual Research Report
  • [Presentation] Metチロシンキナーゼを標的とした低分子抗腫瘍薬開発の試み2011

    • Author(s)
      四ノ宮成祥, 吉森篤史, 高橋哲, 中山昌喜, 松尾洋孝, 守本祐司, 佐伯和徳, 高澤涼子, 田沼靖一
    • Organizer
      第29回日本ヒト細胞学会学術集会
    • Place of Presentation
      富山
    • Related Report
      2011 Annual Research Report
  • [Presentation] ABCG2の遺伝子多型と痛風リスク2011

    • Author(s)
      松尾洋孝
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] 発作性神経疾患をきたす膜輸送体病の病因分子の探索2011

    • Author(s)
      岡田千沙、松尾洋孝、濱田剛、中山昌喜、内海由貴、河村優輔、尾上裕行、海田賢一、守本祐司、小林靖、鎌倉恵子、四ノ宮成祥
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Related Report
      2011 Annual Research Report
  • [Presentation] Molecular pathogenesis for paroxysmal involuntary movements as a channelopathy : genetic analysis of human cases and an animal model2011

    • Author(s)
      H.Matsuo. C.Okada, S.E.Sander, M.Hamann, A.Richter, T.Hamada, A.Nakayama, Y.Utsumi, Y.Kawamura, H.Onoue, K.Kaida, Y.Kobayashi, K. Kamakura, N.Shinomiya
    • Organizer
      2011 International congress of human genetics
    • Place of Presentation
      Montreal, Canada
    • Related Report
      2011 Annual Research Report
  • [Presentation] 発作性ジストニー性舞踊アテトーゼの病因分子の探索;家系症例と疾患モデル動物の遺伝学的解析2011

    • Author(s)
      松尾洋孝, 岡田千沙, 濱田剛, 中山昌喜, 内海由貴, 河村優輔, 尾上裕行, 海田賢一, 守本祐司, 小林靖, 鎌倉恵子, 四ノ宮成祥
    • Organizer
      第56回日本人類遺伝学会・第11回東アジア人類遺伝学会
    • Place of Presentation
      千葉
    • Related Report
      2011 Annual Research Report
  • [Presentation] High Resolution Melting法によるABCG2遺伝子のSNPタイピング2011

    • Author(s)
      高田雄三、松尾洋孝、藤井安宇美、井上寛規、中山昌喜、松村耕治、鈴木洋史、濱嶋信之、四ノ宮成祥、丹羽和紀、小林靖
    • Organizer
      日本DNA多型学会第20回学術集会
    • Place of Presentation
      横浜
    • Related Report
      2011 Annual Research Report
  • [Presentation] 痛風のゲノムワイド関連解析(第1報)2011

    • Author(s)
      松尾洋孝、山本健、中山昌喜、市田公美、清水徹、高田雄三、中村好宏、中島宏、櫻井裕、四ノ宮成祥
    • Organizer
      「ゲノム支援」拡大班会議
    • Place of Presentation
      大阪
    • Related Report
      2011 Annual Research Report
  • [Presentation] 痛風リスク遺伝子検査法の確立2011

    • Author(s)
      高田雄三、松尾洋孝、中山昌喜、河村優輔、井上寛規、松村耕治、四ノ宮成祥、小林靖
    • Organizer
      第22回生物試料分析科学会年次学術集会
    • Place of Presentation
      福岡
    • Related Report
      2011 Annual Research Report
  • [Presentation] 痛風の主要病因遺伝子ABCG2の同定と分子遺伝疫学的解析2011

    • Author(s)
      松尾洋孝, 高田龍平, 市田公美, 中村好宏, 中島宏, 中山昌喜, 井上寛規, 高田雄三, 若井建志, 内藤真理子, 細谷龍男, 鈴木洋史, 櫻井裕, 浜島信之, 四ノ宮成祥
    • Organizer
      第21回日本疫学会学術総会
    • Place of Presentation
      札幌
    • Related Report
      2010 Annual Research Report
  • [Presentation] 痛風の主要病因遺伝子ABCG2の臨床遺伝学的解析2011

    • Author(s)
      松尾洋孝, 市田公美, 清水徹, 高田龍平, 中村好宏, 中山昌喜, 高田雄三, 井上寛規, 櫻井裕, 金井好克, 鈴木洋史, 浜島信之, 細谷龍男, 四ノ宮成祥
    • Organizer
      第44回日本痛風・核酸代謝学会総会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 痛風・高尿酸血症リスク遺伝子における迅速遺伝子検査法の確立2011

    • Author(s)
      高田雄三, 松尾洋孝, 中山昌喜, 井上寛規, 四ノ宮成祥, 鈴木晟幹
    • Organizer
      第8回臨床福祉研究学術集会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] ABCG2/BCRP as a major cause for gout2011

    • Author(s)
      Hirotaka Matsuo, Tappei Takada, Kimiyoshi Ichida, Takahiro Nakamura, Hiroshi Suzuki, Tatsuo Hosoya, Nariyoshi Shinomiya
    • Organizer
      14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP 11
    • Place of Presentation
      Tokyo(招待講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Identification of ABCG2 as a major cause for gout2011

    • Author(s)
      Hirotaka Matsuo, Tappei Takada, Kimiyoshi Ichida, Takahiro Nakamura, Akiyoshi Nakayama, Yuzo Takada, Yutaka Sakurai, Tatsuo Hosoya, Yoshikatsu Kanai, Hiroshi Suzuki, Nariyoshi Shinomiya
    • Organizer
      14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP 11
    • Place of Presentation
      Tokyo
    • Related Report
      2010 Annual Research Report
  • [Presentation] ABCG2 is a high-capacity urate transporter and its genetic impairment increase serum uric acid levels in humans2011

    • Author(s)
      Akiyoshi Nakayama, Hirotaka Matsuo, Tappei Takada, Kimiyoshi Ichida, Takahiro Nakamura, Yuki Ikebuchi, Kousei Ito, Tatsuo Hosoya, Yoshikatsu Kanai, Hiroshi Suzuki, Nariyoshi Shinomiya
    • Organizer
      14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP11
    • Place of Presentation
      Tokyo
    • Related Report
      2010 Annual Research Report
  • [Presentation] Pathogenic GLUT9 mutations causing renal hypouricemia type 2 (RHUC2)2011

    • Author(s)
      Yusuke Kawamura, Hirotaka Matsuo, Toshinori Chiba, Shushi Nagamori, Akiyoshi Nakayama, Hiroki Inoue, Yoshitaka Utsumi, Takashi Oda, Junichiro Nishiyama, Yoshikatsu Kanai, Nariyoshi Shinomiya
    • Organizer
      14th International Symposium on Purine and Pyrimidine Metabolism in Man, PP 11
    • Place of Presentation
      Tokyo
    • Related Report
      2010 Annual Research Report
  • [Presentation] 痛風の主要原因遺伝子ABCG2の同定2010

    • Author(s)
      松尾洋孝
    • Organizer
      第15回千葉尿酸懇話会
    • Place of Presentation
      千葉
    • Year and Date
      2010-11-25
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風の主要原因遺伝子ABCG2の同定2010

    • Author(s)
      松尾洋孝
    • Organizer
      第15回千葉尿酸懇話会
    • Place of Presentation
      千葉(招待講演)
    • Year and Date
      2010-11-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] シンポジウム; トランスポーター研究から生活習慣病克服を目指す, 生活習慣病発症に関わる尿酸トランスポーター ~ゲノムワイド解析後の新展開~2010

    • Author(s)
      松尾洋孝
    • Organizer
      第64回日本栄養・食糧学会大会
    • Place of Presentation
      徳島
    • Year and Date
      2010-05-23
    • Related Report
      2012 Final Research Report
  • [Presentation] シンポジウム;トランスポーター研究から生活習慣病克服を目指す,生活習慣病発症に関わる尿酸トランスポーター-ゲノムワイド解析後の新展開-2010

    • Author(s)
      松尾洋孝, 高田龍平, 市田公美, 鈴木洋史, 四ノ宮成祥
    • Organizer
      第64回日本栄養・食糧学会大会
    • Place of Presentation
      徳島(招待講演)
    • Year and Date
      2010-05-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] 痛風遺伝子の解明とオーダーメイド医療の可能性~生活習慣病で初の主要病因遺伝子~2010

    • Author(s)
      松尾洋孝
    • Organizer
      第1回 所沢生活習慣病研究会
    • Place of Presentation
      川越
    • Year and Date
      2010-05-17
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風遺伝子の解明とオーダーメイド医療の可能性-生活習慣病で初の主要病因遺伝子-2010

    • Author(s)
      松尾洋孝
    • Organizer
      第1回所沢生活習慣病研究会
    • Place of Presentation
      川越(招待講演)
    • Year and Date
      2010-05-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] 痛風原因遺伝子の解明2010

    • Author(s)
      松尾洋孝
    • Organizer
      第1回 佐賀尿酸研究会
    • Place of Presentation
      佐賀
    • Year and Date
      2010-04-01
    • Related Report
      2012 Final Research Report
  • [Presentation] 痛風原因遺伝子の解明2010

    • Author(s)
      松尾洋孝
    • Organizer
      第1回佐賀尿酸研究会
    • Place of Presentation
      佐賀(招待講演)
    • Year and Date
      2010-04-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] hypouricemia type 22010

    • Author(s)
      Kawamura Y, Matsuo H
    • Organizer
      Gordon Research Conferences on Membrane Transport Proteins
    • Place of Presentation
      Biddeford, ME, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2/BCRP is a high-capacity urate transporter and its common variant increases serum uric acid levels in humans2010

    • Author(s)
      Nakayama A, Matsuo H
    • Organizer
      Gordon Research Conference on Membrane Transport Proteins
    • Place of Presentation
      Biddeford, ME, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] Common variants of ABCG2/BCRP cause gout2010

    • Author(s)
      Matsuo H
    • Organizer
      Gordon Research Conference on Membrane Transport Proteins
    • Place of Presentation
      Biddeford, ME, USA
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] ABCG2/BCRP encodes a high-capacity urate transporter and its common variant increases serum uric acid levels in humans2010

    • Author(s)
      Inoue H, Matsuo H
    • Organizer
      American Society of Human Genetics Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Related Report
      2012 Final Research Report
  • [Presentation] ABCG2/BCRP as a major causative gene for gout2010

    • Author(s)
      Matsuo H
    • Organizer
      2010 American Society of Human Genetics Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] ABCG2/BCRPは痛風の主要な病因遺伝子である2010

    • Author(s)
      中山昌喜, 松尾洋孝
    • Organizer
      第5回トランスポーター研究会年会
    • Place of Presentation
      東京(最優秀発表賞・受賞)
    • Related Report
      2012 Final Research Report 2010 Annual Research Report
  • [Presentation] シンポジウム; 疾患の原因そして治療の標的分子としてのトランスポーター, Idetification of ABCG2/BCRP as major cause for gout2010

    • Author(s)
      Matsuo H
    • Organizer
      日本薬物動態学会第25回年会
    • Place of Presentation
      東京
    • Related Report
      2012 Final Research Report
  • [Presentation] 尿酸排出トランスポーターABCG2/BCRPは痛風の主要病因遺伝子である2010

    • Author(s)
      高田龍平, 松尾洋孝, 市田公美, 中村好宏, 池淵祐樹, 伊藤晃成, 四ノ宮成祥, 鈴木洋史
    • Organizer
      日本薬剤学会第25回年会
    • Place of Presentation
      徳島
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular mechanism of urate reabsorption and excretion in humans2010

    • Author(s)
      Hirotaka Matsuo, Tappei Takada, Kimiyoshi Ichida, Takahiro Nakamura, Akiyoshi Nakayama, Yuki Ikebuchi, Kousei Ito, Yuzo Takada, Hiroki Inoue, Yutaka Sakurai, Tatsuo Hosoya, Hiroshi Suzuki, Nariyoshi Shinomiya
    • Organizer
      第87回日本生理学会大会
    • Place of Presentation
      盛岡
    • Related Report
      2010 Annual Research Report
  • [Presentation] シンポジウム;疾患の原因そして治療の標的分子としてのトランスポーター, Idetification of ABCG2/BCRP as major cause for gout2010

    • Author(s)
      Hirotaka Matsuo, Tappei Takada, Kimiyoshi Ichida, Hiroshi Suzuki, Nariyoshi Shinomiya
    • Organizer
      日本薬物動態学会第25回年会
    • Place of Presentation
      東京(招待講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] 痛風の主要病因遺伝子ABCG2/BCRPの同定2010

    • Author(s)
      松尾洋孝, 高田龍平, 市田公美, 中村好宏, 中山昌喜, 高田雄三, 井上寛規, 櫻井裕, 細谷龍男, 金井好克, 鈴木洋史, 四ノ宮成祥
    • Organizer
      日本人類遺伝学会第55回大会
    • Place of Presentation
      大宮
    • Related Report
      2010 Annual Research Report
  • [Presentation] ABCG2/BCRP, a high-capacity urate transporter, is a major causative gene for gout2010

    • Author(s)
      Tappei Takada, Hirotaka Matsuo, Kimiyoshi Ichida, Nariyoshi Shinomiya, Hiroshi Suzuki
    • Organizer
      第4回次世代を担う若手医療薬科学シンポジウム
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] 尿酸排出トランスポーターABCG2は痛風の主要な病因遺伝子である2010

    • Author(s)
      高田龍平, 松尾洋孝, 市田公美, 四ノ宮成祥, 鈴木洋史
    • Organizer
      第32回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      富山
    • Related Report
      2010 Annual Research Report
  • [Presentation] 痛風の主要病因遺伝子の探索と同定2010

    • Author(s)
      松尾洋孝, 高田龍平, 市田公美, 中村好宏, 中山昌喜, 池淵祐樹, 伊藤晃成, 高田雄三, 井上寛規, 河村優輔, 内海由貴, 櫻井裕, 細谷龍男, 金井好克, 鈴木洋史, 四ノ宮成祥
    • Organizer
      BMB2010(第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会)
    • Place of Presentation
      神戸
    • Related Report
      2010 Annual Research Report
  • [Presentation] (学会賞・受賞)ABCG2/BCRP is a high-capacity urate transporter and its common variant increases serum uric acid levels in humans2010

    • Author(s)
      Akiyoshi Nakayama, Hirotaka Matsuo, Tappei Takada, Kimiyoshi Ichida, Takahiro Nakamura, Yuki Ikebuchi, Kousei Ito, Tatsuo Hosoya, Yoshikatsu Kanai, Hiroshi Suzuki, Nariyoshi Shinomiya
    • Organizer
      Gordon Research Conference on Membrane Transport Proteins
    • Place of Presentation
      Biddeford, ME, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] Pathogenic GLUT9 mutations in renal hypouricemia type 2, Gordon Research Conference on Membrane Transport Proteins2010

    • Author(s)
      Yusuke Kawamura, Hirotaka Matsuo, Toshinori Chiba, Shushi Nagamori, Akiyoshi Nakayama, Hiroki Inoue, Hideharu Domoto, Yuichi Kikuchi, Takashi Oda, Junichiro Nishiyama, Yoshikatsu Kanai, Nariyoshi Shinomiya
    • Organizer
      Gordon Research Conference on Membrane Transport Proteins
    • Place of Presentation
      Biddeford, ME, USA
    • Related Report
      2010 Annual Research Report
  • [Presentation] ABCG2/BCRP encodes a high-capacity urate transporter and its common variant increases serum uric acid levels in humans2010

    • Author(s)
      Hiroki Inoue, Hirotaka Matsuo, Tappei Takada, Kimiyoshi Ichida, Takahiro Nakamura, Akiyoshi Nakayama, Koji Suzuki, Tatsuo Hosoya, Hiroshi Suzuki, Nobuyuki Hamajima, Nariyoshi Shinomiya
    • Organizer
      2010 American Society of Human Genetics Annual Meeting
    • Place of Presentation
      Washington DC, USA
    • Related Report
      2010 Annual Research Report
  • [Book] ABCG2と高尿酸血症高尿酸血症と痛風2013

    • Author(s)
      中山昌喜, 松尾洋孝
    • Publisher
      メディカルレビュー社
    • Related Report
      2012 Final Research Report
  • [Book] 一週一話2013

    • Author(s)
      高田龍平, 松尾洋孝
    • Publisher
      日本医事新報社
    • Related Report
      2012 Final Research Report
  • [Book] 尿酸動態の支配要因としての尿酸トランスポーター2012

    • Author(s)
      松尾洋孝
    • Publisher
      細胞工学
    • Related Report
      2012 Final Research Report
  • [Book] 日本臨床2012

    • Author(s)
      千葉俊周,松尾洋孝
    • Publisher
      遺伝性腎性低尿酸血症
    • Related Report
      2012 Final Research Report
  • [Book] 腎と透析2012

    • Author(s)
      千葉俊周,松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 腎疾患治療マニュアル2012-132012

    • Author(s)
      中山昌喜, 松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] Annual Review 糖尿病・代謝・内分泌.腎性低尿酸血症の遺伝学2012

    • Author(s)
      松尾洋孝
    • Publisher
      中外医薬社
    • Related Report
      2012 Final Research Report
  • [Book] 臨床医のための高尿酸血症・痛風のABC2012

    • Author(s)
      松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 細胞工学2012

    • Author(s)
      松尾洋孝, 市田公美, 高田龍平, 中山昌喜, 四ノ宮成祥
    • Publisher
      秀潤社(印刷中)
    • Related Report
      2011 Annual Research Report
  • [Book] 尿酸2011

    • Author(s)
      松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 痛風・高尿酸血症の原因遺伝子(ABCG2)2011

    • Author(s)
      高田雄三,松尾洋孝
    • Publisher
      Medical Technology
    • Related Report
      2012 Final Research Report
  • [Book] 尿酸排出トランスポーターABCG2/BCRPと痛風発症リスク. 生化学2011

    • Author(s)
      高田雄三,松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 第7章 尿酸のトランスポーター. 栄養・食品機能とトランスポーター2011

    • Author(s)
      松尾洋孝
    • Publisher
      建帛社
    • Related Report
      2012 Final Research Report
  • [Book] 遺伝子医学MOOK2011

    • Author(s)
      松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 尿酸輸送. トランスポートソームの世界 -膜輸送研究の源流から未来へ-2011

    • Author(s)
      松尾洋孝
    • Publisher
      京都廣川書店
    • Related Report
      2012 Final Research Report
  • [Book] トランスポートソーム・生体膜輸送機構の全体像に迫る-基礎、臨床、創薬応用研究の最新成果(遺伝子医学MOOK 19号)2011

    • Author(s)
      松尾洋孝
    • Total Pages
      10
    • Publisher
      メディカルドゥ
    • Related Report
      2010 Annual Research Report
  • [Book] トランスポートソームの世界-膜輸送体研究の源流から未来へ-2011

    • Author(s)
      松尾洋孝
    • Total Pages
      13
    • Publisher
      京都廣川書店
    • Related Report
      2010 Annual Research Report
  • [Book] Annual Review 腎臓 20102010

    • Author(s)
      松尾洋孝
    • Publisher
      中外医薬社
    • Related Report
      2012 Final Research Report
  • [Book] 痛風の病因遺伝子. 痛風と核酸代謝2010

    • Author(s)
      松尾洋孝
    • Related Report
      2012 Final Research Report
  • [Book] 痛風の主要な病因遺伝子ABCG2の同定. 実験医学2010

    • Author(s)
      松尾洋孝
    • Publisher
      羊土社
    • Related Report
      2012 Final Research Report
  • [Book] 遺伝要因. 内科系総合雑誌Modern Physician2010

    • Author(s)
      中山昌喜, 松尾洋孝
    • Publisher
      新興医学出版社
    • Related Report
      2012 Final Research Report
  • [Book] 痛風の遺伝子. リウマチ科2010

    • Author(s)
      中山昌喜, 松尾洋孝
    • Publisher
      科学評論社
    • Related Report
      2012 Final Research Report
  • [Book] 実験医学2010

    • Author(s)
      松尾洋孝, 高田龍平, 市田公美, 中村好宏, 鈴木洋史, 四ノ宮成祥
    • Total Pages
      5
    • Publisher
      羊土社
    • Related Report
      2010 Annual Research Report
  • [Remarks] 現在、研究内容および研究成果に関するwebページを作成中である。

    • Related Report
      2011 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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