Elucidation of the mechanism of in vivo ketogenesis by astrocytes
Project/Area Number |
22689028
|
Research Category |
Grant-in-Aid for Young Scientists (A)
|
Allocation Type | Single-year Grants |
Research Field |
Neurology
|
Research Institution | Keio University |
Principal Investigator |
NAKAHARA Jin 慶應義塾大学, 医学部, 特任講師 (60537950)
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥25,090,000 (Direct Cost: ¥19,300,000、Indirect Cost: ¥5,790,000)
Fiscal Year 2012: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2011: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2010: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
|
Keywords | 神経分子病態学 / 脳代謝 / アストロサイト / ケトン体 / 遺伝子改変マウス / HMGCS2 / Conditionl KOマウス |
Research Abstract |
Regulation of brain metabolism is critical in the treatment or prevention of neurological diseases or in future regenerative medicine in central nervous system. Recently, ketone bodies were shown to have a pivotal role in brain metabolism and act as a neu
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Report
(4 results)
Research Products
(18 results)