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Identifying genetic factors for deficits in interpersonal behaviors by utilizing multimodal Magnetic Resonance Imaging

Research Project

Project/Area Number 22689034
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Psychiatric science
Research InstitutionThe University of Tokyo

Principal Investigator

YAMASUE Hidenori  東京大学, 医学部附属病院, 准教授 (80436493)

Project Period (FY) 2010-04-01 – 2014-03-31
Project Status Completed (Fiscal Year 2013)
Budget Amount *help
¥25,220,000 (Direct Cost: ¥19,400,000、Indirect Cost: ¥5,820,000)
Fiscal Year 2013: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2012: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2011: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2010: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
Keywords社会性の障害 / 自閉症スペクトラム障害 / 統合失調症 / オキシトシン受容体遺伝子多型 / 内側前頭前野 / 島皮質 / 自閉症的社会行動傾向 / Nーアセチルアスパラギン酸 / グルタミン酸-グルタミン総和 / 批判的な聴覚言葉 / 対人行動 / 自閉症 / 広汎性発達障害 / MRI / functional MRI / MR-spectroscopy / 中間表現型 / 脳画像 / 対人行動の障害 / 男女差 / マルチモダリティ脳MRI / ゲノム要因 / マルチモダリティ脳MRI解析
Research Abstract

This study project revealed associations between OXTR rs2254298a, a risk allele for autism spectrum disorders (ASD) in Asian populations, and regional gray matter volumes in limbic and paralimbic brain structures (Biol Psychiatry 2010a; 2011; SCAN 2013). Effects of exogenous oxytocin on phenotype/endophenotype of oxytocin related genetic factors were further tested by conducting a randomized controlled double-blind trial (J Neurosci 2012; JAMA psychiatry 2014). Furthermore, common and distinct contributions of medial prefrontal and inferior frontal cortices to the brain pathophysiology for schizophreina and ASD were revealed (e.g. Biol Psychiatry 2010b; Transl Psychiatry 2012; Schizophr Bull 2013).

Report

(5 results)
  • 2013 Annual Research Report   Final Research Report ( PDF )
  • 2012 Annual Research Report
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (140 results)

All 2014 2013 2012 2011 2010 Other

All Journal Article (61 results) (of which Peer Reviewed: 56 results,  Open Access: 3 results) Presentation (65 results) (of which Invited: 10 results) Book (14 results)

  • [Journal Article] Two distinct neural mechanisms underlying indirect reciprocity2014

    • Author(s)
      Watanabe T, Takezawa M, Nakawake Y, Kunimatsu A, Yamasue H, Nakamura M, et al
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 111(11) Issue: 11 Pages: 3990-3995

    • DOI

      10.1073/pnas.1318570111

    • Related Report
      2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A snapshot of plasma metabolites in first-episode schizophrenia : A capillary electrophoresis time-of-flight mass spectrometry study (131 characters)2014

    • Author(s)
      Koike S, Bundo M, Iwamoto K, Suga M, Kuwabara H, Ohashi Y, Shinoda K, Takano Y, Iwashiro N, Satomura Y, Nagai T, Natsubori T, Tada M, Yamasue H, and Kasai K
    • Journal Title

      Translational Psychiatry

      Volume: 4 Issue: 4 Pages: e379-e379

    • DOI

      10.1038/tp.2014.19

    • Related Report
      2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of decreased prefrontal hemodynamic response during a verbal fluency task with EGR3 gene polymorphism in patients with schizophrenia and in healthy individuals2014

    • Author(s)
      Nishimura Y, Takizawa R, Koike S, Kinoshita A, Satomura Y, Kawasaki S, Yamasue H, Tochigi M, Kakiuchi C, Sasaki T, Iwayama Y, Yamada K, Yoshikawa T, and Kasai K
    • Journal Title

      NeuroImage

      Volume: 1 Pages: 527-34

    • DOI

      10.1016/j.neuroimage.2013.08.021

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Aberrant interference of auditory negative words on attention in patients with schizophrenia2013

    • Author(s)
      Iwashiro N, Yahata N, Kawamuro Y, Kasai K, and Yamasue H
    • Journal Title

      PLOS ONE

      Volume: 8 Issue: 12 Pages: e83201-e83201

    • DOI

      10.1371/journal.pone.0083201

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Prefrontal activation during inhibitory control measured by near-infrared spectroscopy for differentiating between autism spectrum disorders and attention deficit hyperactivity disorder in adults2013

    • Author(s)
      Ishii-Takahashi A, Takizawa R, Nishimura Y, Kawakubo Y, Kuwabara H, Matsubayashi J, Hamada K, Okuhata S, Yahata N, Igarashi T, Kawasaki S, Yamasue H, Kato N, Kasai K, and Kano Y
    • Journal Title

      Neuroimage : Clinical

      Volume: 4 Pages: 53-63

    • DOI

      10.1016/j.nicl.2013.10.002

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural correlate of autistic-like traits and a common allele in the oxytocin receptor gene2013

    • Author(s)
      Saito Y, Suga M, Tochigi M, Abe O, Yahata N, Kawakubo Y, Liu X, Kawamura Y, Sasaki T, Kasai K, and Yamasue H
    • Journal Title

      Social Cognitive and Affective Neuroscience

      Volume: (published online) Issue: 10 Pages: 1443-1450

    • DOI

      10.1093/scan/nst136

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reduced frontal Glutamate+Glutamine and N-acetylaspartate levels in patients with chronic schizophrenia but not in those at clinical-high risk for psychosis or with first-episode schizophrenia2013

    • Author(s)
      Natsubori T, Inoue H, Abe O, Takano Y, Iwashiro N, Aoki Y, Koike S, Yahata N, Katsura M, Gonoi W, Sasaki H, Takao H, Kasai K, and Yamasue H
    • Journal Title

      Schizophrenia Bulletin

      Volume: (published online) Issue: 5 Pages: 1128-1139

    • DOI

      10.1093/schbul/sbt124

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Altered metabolites in the plasma of autism spectrum disorder : a capillary electrophoresis time-of-flight mass spectroscopy study2013

    • Author(s)
      Kuwabara H, Yamasue H, Koike S, Inoue H, Kawakubo Y, Kuroda M, Takano Y, Iwashiro N, Natsubori T, Aoki Y, Kano Y, and Kasai K
    • Journal Title

      PLOS ONE

      Volume: 8 Issue: 9 Pages: e73814-e73814

    • DOI

      10.1371/journal.pone.0073814

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural bases of antisocia behavior : a voxel-based meta-analysis2013

    • Author(s)
      Aoki Y, Inokuchi R, Nakao T and Yamasue H
    • Journal Title

      Social Cognitive and Affective Neuroscience

      Volume: (published online) Issue: 8 Pages: 1223-1231

    • DOI

      10.1093/scan/nst104

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mitigation of Sociocommunicational Deficits of Autism Through Oxytocin-Induced Recovery of Medial Prefrontal Activity : A Randomized Trial2013

    • Author(s)
      Watanabe T, Abe O, Kuwabara H, Yahata N, Takano Y, Iwashiro N, Natsubori T, Aoki Y, Takao H, Kawakubo Y, Kamio Y, Kato N, Miyashita Y, Kasai K, and Yamasue H
    • Journal Title

      JAMA psychiatry

      Volume: 71 Issue: 2 Pages: 166-75

    • DOI

      10.1001/jamapsychiatry.2013.3181

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of white matter integrity between autism spectrum disorder subjects and typically developing individuals. A meta-analysis of diffusion tensor imaging tractography studies2013

    • Author(s)
      Aoki Y, Abe O, Nippashi Y and Yamasue H
    • Journal Title

      Molecular Autism

      Volume: 4(1) Issue: 1 Pages: 25-25

    • DOI

      10.1186/2040-2392-4-25

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Volume reductions in frontopolar and left perisylvian cortices in methamphetamine induced psychosis2013

    • Author(s)
      Aoki Y, Orikabe L, Takayanagi Y, Yahata N, Mozue Y, Sudo Y, Ishii T, Itokawa M, Suzuki M, Kurachi M, Okazaki Y, Kasai K, Yamasue H
    • Journal Title

      Schizophrenia Research

      Volume: 147 Issue: 2-3 Pages: 355-361

    • DOI

      10.1016/j.schres.2013.04.029

    • Related Report
      2013 Annual Research Report 2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Network structure underlying resolution of conflicting nonverbal and verbal social information.2013

    • Author(s)
      渡部喬光
    • Journal Title

      Social Cognition and Affective Neuroscience

      Volume: (掲載確定) Issue: 6 Pages: 767-775

    • DOI

      10.1093/scan/nst046

    • Related Report
      2013 Annual Research Report 2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Absence of age-related prefrontal NAA change in adults with autism spectrum disorders2013

    • Author(s)
      Aoki, Y., Abe, O., Yahata, N., Kuwabara, H., Natsubori, T., Iwashiro, N., Takano, Y., Inoue,H., Kawakubo, Y., Gonoi, W., Sasaki, H., Murakami, M., Katsura, M., Nippashi, Y., Takao, H., Kunimatsu, A., Matsuzaki, H., Tsuchiya, K. J., Kato, N., Kasai, K. & Yamasue, H
    • Journal Title

      Transl Psychiatry

      Volume: 2 Issue: 10 Pages: e178-e178

    • DOI

      10.1038/tp.2012.108

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Function and structure in social brain regions can link oxytocin-receptor genes with autistic social behavior.2013

    • Author(s)
      Yamasue H(First & Corresponding author)
    • Journal Title

      Brain and Development

      Volume: 35 Issue: 2 Pages: 111-118

    • DOI

      10.1016/j.braindev.2012.08.010

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Volume reductions in frontopolar and left perisylvian cortices in methamphetamine induced psychosis.2013

    • Author(s)
      Aoki Y, (途中11名), Yamasue H (Last & Corresponding author)
    • Journal Title

      Schizophrenia Research

      Volume: 印刷中

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A multimodal approach to investigate biomarkers for psychosis in a clinical setting: the integrative neuroimaging studies in schizophrenia targeting for early intervention and prevention (IN-STEP) project2013

    • Author(s)
      Koike, S., Takano, Y., Iwashiro, N., Satomura, Y., Suga, M., Nagai, T., Natsubori, T., Tada, M., Nishimura, Y., Yamasaki, S., Takizawa, R., Yahata, N., Araki, T., Yamasue, H. & Kasai, K
    • Journal Title

      Schizophr Res

      Volume: 143(1) Issue: 1 Pages: 116-24

    • DOI

      10.1016/j.schres.2012.11.012

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Anxiety and Performance: The disparate roles of prefrontal sub-regions under maintained psychological stress.2013

    • Author(s)
      Takizawa R, Nishimura Y, Yamasue H, Kasai K
    • Journal Title

      Cerebral Cortex

      Volume: Advanced online publication Issue: 7 Pages: 1858-1866

    • DOI

      10.1093/cercor/bht036

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Genetic influences on prefrontal activation during a verbal fluency task in adults: A twin study based on multichannel near-infrared spectroscopy.2013

    • Author(s)
      Sakakibara E, (途中19名), Yamasue H, (以下9名)
    • Journal Title

      Neuroimage

      Volume: Advanced online publication Pages: 508-517

    • DOI

      10.1016/j.neuroimage.2013.03.052

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical and psychosocial characteristics in adults with pervasive development disorders : A survey in Japan2012

    • Author(s)
      Yukawa Y, Ota H, Kanai C, Tani M, Yamada T, Hashimoto R, Yamasue H, Kato N, Iwanami A
    • Journal Title

      International Journal on Disability and Human Development

      Volume: 12 Issue: 1 Pages: 25-29

    • DOI

      10.1515/ijdhd-2012-0121

    • Related Report
      2013 Final Research Report
  • [Journal Article] Localized gray matter volume reductions in the pars triangularis of the inferior frontal gyrus in individuals at clinical high-risk for psychosis and first episode for schizophrenia2012

    • Author(s)
      Iwashiro, N., Suga, M., Takano, Y., Inoue, H., Natsubori, T., Satomura, Y., Koike, S., Yahata, N., Murakami, M., Katsura, M., Gonoi, W., Sasaki, H., Takao, H., Abe, O., Kasai, K. & Yamasue, H
    • Journal Title

      Schizophr Res

      Volume: 137(1-3) Issue: 1-3 Pages: 124-31

    • DOI

      10.1016/j.schres.2012.02.024

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Age-related change in brain metabolite abnormalities in autism : A meta-analysis of proton magnetic resonance spectroscopy studies2012

    • Author(s)
      Aoki Y, Kasai K, Yamasue H
    • Journal Title

      Translational Psychiatry

      Volume: 2 Issue: 1 Pages: e69-e69

    • DOI

      10.1038/tp.2011.65

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
  • [Journal Article] Diminished Medial Prefrontal Activity Behind Autistic Social Judgments of Incongruent Information.2012

    • Author(s)
      渡部喬光
    • Journal Title

      PLoS One

      Volume: 7 Issue: 6 Pages: e39561-e39561

    • DOI

      10.1371/journal.pone.0039561

    • Related Report
      2013 Final Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Integrative approaches utilizing oxytocin to enhance prosocial behavior: from animal and human social behavior to autistic social dysfunction.2012

    • Author(s)
      Yamasue H(以下6名)(First & Corresponding author)
    • Journal Title

      The Jounal of Neuroscience

      Volume: 32 Issue: 41 Pages: 14109-14117

    • DOI

      10.1523/jneurosci.3327-12.2012

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tract-specific analysis of white matter integrity disruption in schizophrenia2012

    • Author(s)
      Kunimatsu N, Aoki S, Kunimatsu A, Abe O, et al
    • Journal Title

      Psychiatry Res.

      Volume: 201 Issue: 2 Pages: 136-143

    • DOI

      10.1016/j.pscychresns.2011.07.010

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 社会性オキシトシンと神経画像2012

    • Author(s)
      山末英典
    • Journal Title

      Clinical Neuroscience

      Volume: 30 Pages: 209-211

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reply to "Neurogenetic effects of OXTR rs2254298 in the extended limbic system of healthy Caucasian adults"2011

    • Author(s)
      Yamasue H, Suga M, Yahata N, Inoue H, Tochigi M Abe O, Liu X, Kawamura Y, Rogers MA, Takei K, Yamada H, Aoki S, Sasaki T, Kasai K
    • Journal Title

      Biological Psychiatry

      Volume: 70 Issue: 9 Pages: 41-42

    • DOI

      10.1016/j.biopsych.2011.06.034

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reduced amygdala and hippocampal volumes in patients with methamphetamine psychosis2011

    • Author(s)
      Orikabe L, Yamasue H, Inoue H, T Yoichiro, Mozue Y, Sudo Y, Ishii T, Itokawa M, Suzuki M, Kurachi M, Okazaki Y, Kasai K
    • Journal Title

      Schizophrenia Research

      Volume: 132 Issue: 2-3 Pages: 183-189

    • DOI

      10.1016/j.schres.2011.07.006

    • Related Report
      2013 Final Research Report 2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical characteristics of adults with Asperger's Syndrome assessed with self-report questionnaires. Research in Autism Spectrum Disorders2011

    • Author(s)
      Kanai C, H, Yamasue H, 他6名4番目
    • Journal Title

      Research in Autism Spectrum Disorders

      Volume: 5 Issue: 1 Pages: 185-190

    • DOI

      10.1016/j.rasd.2010.03.008

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Task dependent prefrontal dysfunction in persons with Asperger's disorder investigated with multi-channel near-infrared spectroscopy2011

    • Author(s)
      Iwanami A, Yamasue H, 他9名9番目
    • Journal Title

      Research in Autism Spectrum Disorders

      Volume: 5 Issue: 3 Pages: 1187-1193

    • DOI

      10.1016/j.rasd.2011.01.005

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cortical thickness, gray matter volume, and white matter anisotropy and diffusivity in schizophrenia2011

    • Author(s)
      Murakami M, Yamasue H, 他8名4番目
    • Journal Title

      Neuroradiology

      Volume: 53 Issue: 11 Pages: 859-866

    • DOI

      10.1007/s00234-010-0830-2

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] et al. Gray and white matter asymmetries in healthy individuals aged 21-29 years: A voxel-based morphometry and diffusion tensor imaging study2011

    • Author(s)
      Takao H.,Abe O.
    • Journal Title

      Hum Brain Mapp

      Volume: 32 Issue: 10 Pages: 1762-73

    • DOI

      10.1002/hbm.21145

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 【精神発達遅滞・自閉症の分子医学】発達障害・自閉症のゲノム研究自閉症のイメージングジェネティクス2011

    • Author(s)
      山末英典
    • Journal Title

      医学のあゆみ

      Volume: 239 Pages: 733-738

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical characteristics of adults with Asperger's Syndrome assessed with self-report questionnaires.2011

    • Author(s)
      Kanai C, Yamasue H, 他6名4番目
    • Journal Title

      Research in Autism Spectrum Disorders

      Volume: 5 Pages: 185-190

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 自閉症とオキシトシン2011

    • Author(s)
      山末英典, 他1名1番目
    • Journal Title

      Clinical Neuroscience

      Volume: 28 Pages: 1336-1337

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 性差と自閉症2011

    • Author(s)
      山末英典, 他1名1番目
    • Journal Title

      臨床精神医学

      Volume: 40 Pages: 153-160

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] et al Association between the oxytocin receptor gene and amygdalar volume in healthy adults .2010

    • Author(s)
      Inoue H.,Yamasue H.,Tochigi M.,Abe O.
    • Journal Title

      Biol Psychiatry

      Volume: 68 Issue: 11 Pages: 1066-1072

    • DOI

      10.1016/j.biopsych.2010.07.019

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Reduced gray matter volume of Brodmann's Area 45 is associated with severe psychotic symptoms in patients with schizophrenia2010

    • Author(s)
      Suga M, Yamasue H, Abe O, Yamasaki S, Yamada H, Inoue H, Takei K, Aoki S, Kasai K
    • Journal Title

      European Archives of Psychiatry and Clinical Neuroscience

      Volume: 260 Issue: 6 Pages: 465-473

    • DOI

      10.1007/s00406-009-0094-1

    • Related Report
      2013 Final Research Report
  • [Journal Article] Reduced gray matter volume of pars opercularis is associated with impaired social communication in high-functioning autism spectrum disorders2010

    • Author(s)
      Yamasaki, S., Yamasue, H., Abe, O., Suga, M., Yamada, H., Inoue, H., Kuwabara, H., Kawakubo, Y., Yahata, N., Aoki, S., Kano, Y., Kato, N. & Kasai, K
    • Journal Title

      Biol Psychiatry

      Volume: 68 Issue: 12 Pages: 1141-1147

    • DOI

      10.1016/j.biopsych.2010.07.012

    • Related Report
      2013 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of tryptophan hydroxylase-2 gene variants on amygdalar and hippocampal volumes2010

    • Author(s)
      Inoue H, Yamasue H, Tochigi M, Takei K, Suga M, Abe O, Yamada H, Rogers MA, Aoki S, Sasaki T, Kasai K
    • Journal Title

      Brain Research

      Volume: 1331 Pages: 51-57

    • DOI

      10.1016/j.brainres.2010.03.057

    • Related Report
      2013 Final Research Report
  • [Journal Article] Functional (GT)n polymorphismsin promoter region of N-methyl-D-aspartate receptor 2A subunit (GRIN2A) gene affect hippocampal and amygdala volumes2010

    • Author(s)
      Inoue H, Yamasue H, Tochigi M, Suga M, Iwayama Y, Abe O, Yamada H, Rogers MA, Aoki S, Kato T, Sasaki T, Yoshikawa T, Kasai K
    • Journal Title

      Genes, Brain and Behavior

      Volume: 9 Issue: 3 Pages: 269-275

    • DOI

      10.1111/j.1601-183x.2009.00557.x

    • Related Report
      2013 Final Research Report
  • [Journal Article] Functional (GT)n polymorphismsin promoter region of N-methyl-D-aspartate receptor 2A subunit (GRIN2A) gene affect hippocampal and amygdala volumes.2010

    • Author(s)
      Inoue H, Yamasue H, 他11名2番目
    • Journal Title

      Genes, Brain and Behavior

      Volume: 9 Pages: 269-275

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of tryptophan hydroxylase-2 gene variants on amygdalar and hippocampal volumes.2010

    • Author(s)
      Inoue H, Yamasue H, 他9名2番目
    • Journal Title

      Brain Research

      Volume: 1331 Pages: 51-57

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two genetic variants of CD38 in subjects with autism spectrum disorder and controls.2010

    • Author(s)
      Munesue T, Yamasue H, 他53名34番目
    • Journal Title

      Neuroscience Research

      Volume: 67 Pages: 181-191

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Volume reduction and altered sulco-gyral pattern of the orbitofrontal cortex in first-episode schizophrenia.2010

    • Author(s)
      Takayanagi Y, Yamasue H, 他11名10番目
    • Journal Title

      Schizophrenia research

      Volume: 121 Pages: 55-65

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Voxel-based analysis of the diffusion tensor.2010

    • Author(s)
      Abe O, Yamasue H, 他11名10番目
    • Journal Title

      Neuroradiology

      Volume: 52 Pages: 699-710

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reduced gray matter volume of pars opercularis is associated with impaired social communication in high-functioning autism spectrum disorders.2010

    • Author(s)
      Yamasaki S, Yamasue H, 他11名2番目
    • Journal Title

      Biological Psychiatry

      Volume: 68 Pages: 1141-1147

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reduced gray matter volume of Brodmann's Area 45 is associated with severe psychotic symptoms in patients with schizophrenia.2010

    • Author(s)
      Suga M, Yamasue H, 他7名2番目
    • Journal Title

      European Archives of Psychiatry and Clinical Neuroscience

      Volume: 260 Pages: 467-473

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between the oxytocin receptor gene (OXTR) and amygdalar volume in healthy adults.2010

    • Author(s)
      Inoue H, Yamasue H, 他11名2番目
    • Journal Title

      Biological Psychiatry

      Volume: 68 Pages: 1066-1072

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Age-related changes in regional brain volume evaluated by atlas-based method.2010

    • Author(s)
      Gonoi W, Yamasue H, 他7名3番目
    • Journal Title

      Neuroradiology

      Volume: 52 Pages: 865-873

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Frontal dysfunction during a cognitive task in persons with Asperger disorder investigated with multi-channel near-infrared spectroscopy.2010

    • Author(s)
      Iwanami A, Yamasue H, 他8名9番目
    • Journal Title

      International Journal of Psychophysiology

      Volume: 77 Pages: 255-255

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] P3a and P3b of event-related potentials in persons with Asperger disorder.2010

    • Author(s)
      Iwanami A, Yamasue H, 他8名9番目
    • Journal Title

      International Journal of Psychophysiology

      Volume: 77 Pages: 255-256

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Gray and White Matter Asymmetries in Healthy Individuals Aged 21-29Years : A Voxel-Based Morphometry and Diffusion Tensor Imaging Study.2010

    • Author(s)
      Takao H, Yamasue H, 他6名3番目
    • Journal Title

      Human Brain Mapping

      Volume: 30.Sep(Epub)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Continuous positive airway pressure for obstructive sleep apnea improved negative symptoms in a patient with schizophrenia.2010

    • Author(s)
      Sugishita K, Yamasue H, 他1名2番目
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: 64 Pages: 665-665

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cortical thickness, gray matter volume, and white matter anisotropy and diffusivity in schizophrenia.2010

    • Author(s)
      Murakami M, Yamasue H, 他8名4番目
    • Journal Title

      Neuroradiology

      Volume: 7.Jan(Epub)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] アスペルガー障害の形態画像2010

    • Author(s)
      太田晴久、山末英典, 他1名3番目
    • Journal Title

      精神科

      Volume: 16 Pages: 59-65

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 社会行動の障害の脳解剖学的基盤2010

    • Author(s)
      山末英典
    • Journal Title

      実験医学

      Volume: 28 Pages: 712-719

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 自閉症スペクトラム障害の脳科学-社会性の障害に着目して2010

    • Author(s)
      加藤進昌、山末英典, 他3名2番目
    • Journal Title

      BRAIN and NERVE

      Volume: 62 Pages: 975-986

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 精神医学研究における出生コホートの必要性発達環境個体の相互作用の解明2010

    • Author(s)
      西田淳志、山末英典
    • Journal Title

      医学のあゆみ

      Volume: 別冊 Pages: 123-127

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 自閉症スペクトラム障害の脳形態異常とその起源2010

    • Author(s)
      山末英典
    • Journal Title

      医学のあゆみ

      Volume: 別冊 Pages: 128-133

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical and psychosocial characteristics in adults with pervasivedevelopment disorders

    • Author(s)
      Yukawa Y, Yamasue H, 他7名7番目
    • Journal Title

      International Journal on Disability and Human Development

      Volume: (in press)

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] Absence of age-related prefrontal NAA change in adults with autism-spectrum disorders2012

    • Author(s)
      Aoki Y, Abe O, Yahata N, Kuwabara H, Iwashiro N, Natsubori T, Takano Y, Inoue H, Kawakubo Y, Gonoi W, Sasaki H, Murakami M, Katsura M, Nippashi Y, Takao H, Kunimatsu A, Matsuzaki H, Tsuchiya KJ, Kato N, Kasai K, Yamasue H
    • Organizer
      Neuroscience 2012, SfN's 42nd annual meeting
    • Place of Presentation
      New Orleans
    • Year and Date
      2012-10-13
    • Related Report
      2013 Final Research Report
  • [Presentation] Atypical age-related change ofmedial prefrontal N-acetylaspartate in adults with autismspectrum disorder : a protonmagnetic resonance2012

    • Author(s)
      Aoki Y, Abe O, Yahata N, Kuwabara H, Natsubori T, Iwashiro N, Takano Y, Takao H, Kato N, Yamasue H
    • Organizer
      20th WORLD CONGRESS PARIS IACAPAP 2012
    • Place of Presentation
      Paris, France
    • Year and Date
      2012-07-24
    • Related Report
      2013 Final Research Report
  • [Presentation] A Meta Analytic Approach of Proton Magnetic Resonance Spectroscopy Studies to Uncover the Background of Transient Overgrowth of Autistic Brain2012

    • Author(s)
      Aoki Y, Kasai K, Yamasue H
    • Organizer
      2012 SOBP 67th Annual Scientific Convention
    • Place of Presentation
      Philadelphia
    • Year and Date
      2012-05-04
    • Related Report
      2013 Final Research Report
  • [Presentation] Are Autistic Brain Structural Abnormalities Associated with Perinatal and Genetic Factors?2012

    • Author(s)
      Yamasue H, Kuwabara H, Aoki Y, Saito Y, Yahata N, Natsubori T, , Iwashiro N, Takano Y, Inoue H, Nippashi Y, Takao H, Abe O, Sasaki T, Kasai K
    • Organizer
      2012 SOBP 67th Annual Scientific Convention
    • Place of Presentation
      Philadelphia
    • Year and Date
      2012-05-04
    • Related Report
      2013 Final Research Report
  • [Presentation] 双生児研究法による近赤外線スペクトロスコピーの前頭側頭部血流変化における遺伝的要因の検討2012

    • Author(s)
      榊原英輔, 滝沢龍, 西村幸香, 木納賢, 丸茂浩平, 山崎修道, 江口聡, 武井邦夫, 井上秀之, 管心, 山末英典, 川久保友紀, 笠井清登
    • Organizer
      第7回統合失調症学会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-03-17
    • Related Report
      2013 Final Research Report
  • [Presentation] 統合失調症および臨床的ハイリスク群に置ける下前頭回の脳機能・形態異常:言語的情報処理および対人情報処理の障害の脳基盤2012

    • Author(s)
      山末英典
    • Organizer
      第7回統合失調症学会
    • Place of Presentation
      名古屋(招待講演)
    • Year and Date
      2012-03-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 所初統合失調症群と精神病状態の高リスク群に共通して認められる下前頭回における三角部に局限した灰白質体積減少とその陽性症状発現との関連2012

    • Author(s)
      岩白訓周, 管心, 高野洋輔, 井上秀之, 夏堀龍暢, 里村嘉弘, 小池進介, 八幡憲明, 村上瑞穂, 五ノ井渉, 佐々木弘喜, 高尾英正, 阿部修, 笠井清登, 山末英典
    • Organizer
      第7回統合失調症学会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-03-16
    • Related Report
      2013 Final Research Report
  • [Presentation] 初発統合失調症群と精神病状態の高リスク群に共通して認められる下前頭回における三角部に限局した灰白質体積減少とその陽性症状発現との関連2012

    • Author(s)
      岩白訓周、山末英典, 他13名15番目
    • Organizer
      第7回日本統合失調症学会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-03-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] 双生児研究法による新版S タイ状態-特性不安検査と近赤外線スペクトロスコピーにおける遺伝的要因の検討2012

    • Author(s)
      榊原英輔, 滝沢龍, 西村幸香, 木納賢, 丸茂浩平, 山崎修道, 江口聡, 武井邦夫, 井上秀之, 管心, 山末英典, 川久保友紀, 笠井清登
    • Organizer
      第4回日本不安障害学会学術大会
    • Place of Presentation
      東京
    • Year and Date
      2012-02-04
    • Related Report
      2013 Final Research Report
  • [Presentation] “Oxytocin, sexually-dimorphic social brain and behavior”, Symposium “SEARCHING INTERMEDIATE PHENOTYPE: NEUROIMAGING STUDIES TO LINK AUTISTIC BEHAVIORAL DEFICITS WITH HERITABLE FACTORS”2012

    • Author(s)
      Yamasue H
    • Organizer
      20th WORLD CONGRESS PARIS IACAPAP 2012
    • Place of Presentation
      Paris, France
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] Oxytocin, Sexually-dimorphic feature of social brain, and autistic ocial dyfunction2011

    • Author(s)
      Yamasue H
    • Organizer
      Exploring Autism Research Collaboration Between Japan and United States Joint Academic Conference on Autism spectrum Disorders
    • Place of Presentation
      Tokyo, Japan(招待講演)
    • Year and Date
      2011-12-02
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脳神経画像とゲノム2011

    • Author(s)
      山末英典
    • Organizer
      第二回脳表現型の分子メカニズム研究会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-11-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] Investigating neural mechanisms that interface between self and others : An fMRI study on the theory of mind and empathy2011

    • Author(s)
      Yahata N, Yamasue H, Takano Y, Kawakubo Y, Inoue H, Iwashiro N, Natsubori T, Aoki Y, Takao H, Sasaki H, Gonoi W, Katsura M, Murakami M, Kunimatsu A, Abe O, Kasai K
    • Organizer
      Neuroscience 2011, SfN's 41th annual meeting
    • Place of Presentation
      Washington, DC
    • Year and Date
      2011-11-16
    • Related Report
      2013 Final Research Report
  • [Presentation] Investigating neural mechanisms that interface between self and others : An fMRI study on the theory of mind and empathy2011

    • Author(s)
      Yahata N, Yamasue H, 他14名2番目
    • Organizer
      SfN's 41th annual meeting
    • Place of Presentation
      Washington, DC, USA
    • Year and Date
      2011-11-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Intranasal administration of oxytocin recovers deficits in social interaction with increase of originally decreased medial prefrontal activity in autism spectrum disorder2011

    • Author(s)
      Yamasue H, Wtanabe T, Abe O. Yahata N, Kuwabara H, Inoue H, Takanano Y, Iwashiro N, Natsubori T, Aoki Y, Takao H, Sasaki H, Gonoi W, Murakami M, Katsura M, Kunimatsu A, Kawakubo Y, Ando T, Suga M, Matsuzaki H, Tsuchiya K, Kamio Y, Kato N, Kano Y, Miyashita Y, Kasai K
    • Organizer
      Neuroscience 2011, SfN's 41th annual meeting
    • Place of Presentation
      Washington, DC
    • Year and Date
      2011-11-15
    • Related Report
      2013 Final Research Report
  • [Presentation] Intranasal administration of oxytocin recovers deficits in social interaction with increase of originally decreased medial pre frontal activity in autism spectrum disorder2011

    • Author(s)
      Yamasue H, 他25名
    • Organizer
      Neuroscience 2011, SfN's 41th annual meeting
    • Place of Presentation
      Washington, DC, USA
    • Year and Date
      2011-11-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] 広汎性発達障害当事者に対する心理社会的介入プログラムによる有効性の検討と精神的ケア向上に関する研究2011

    • Author(s)
      山末英典
    • Organizer
      第18回ヘルスリサーチフォーラム
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Related Report
      2011 Annual Research Report
  • [Presentation] 自閉症の社会行動障害の脳神経基盤2011

    • Author(s)
      山末英典
    • Organizer
      第21回日本臨床精神神経薬理学会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-10-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] 精神疾患研究における脳MRI解析の果たす役割2011

    • Author(s)
      笠井清登、八幡憲明、山末英典
    • Organizer
      第39回日本磁気共鳴医学会大会
    • Place of Presentation
      小倉
    • Year and Date
      2011-09-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] Voxel-based Morphometryを応用した対人行動とその障害の脳神経基盤の研究2011

    • Author(s)
      山末英典
    • Organizer
      第39回日本磁気共鳴医学会大会
    • Place of Presentation
      小倉(招待講演)
    • Year and Date
      2011-09-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 精神疾患におけるDTI解析成果2011

    • Author(s)
      阿部修、山末英典、笠井清登、青木茂樹
    • Organizer
      第39回日本磁気共鳴医学会大会
    • Place of Presentation
      小倉
    • Year and Date
      2011-09-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] 広汎性発達障害成人の脳画像研究からわかること2011

    • Author(s)
      山末英典
    • Organizer
      国立精神・神経センター「第4回発達障害精神医療研修」
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-09-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] Oxytocin and ASD, Imaging Genetics and Pharmacotherapeutic Implication2011

    • Author(s)
      Yamasue H
    • Organizer
      2^<nd> Congress of AsCNP
    • Place of Presentation
      Seoul, South Korea(招待講演)
    • Year and Date
      2011-09-24
    • Related Report
      2011 Annual Research Report
  • [Presentation] 自閉症当事者の内側前頭前野における神経科学的変化2011

    • Author(s)
      青木悠太, 山末英典, 阿部修, 八幡憲明, 夏堀龍暢, 岩白訓周, 高野洋輔, 井上秀之, 桑原斉, 川久保友紀, 五ノ井渉, 佐々木弘喜, 村上瑞穂, 桂正樹, 新橋靖真, 高尾英正, 国松聡, 松崎秀夫, 土屋賢治, 笠井清登
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-17
    • Related Report
      2013 Final Research Report 2011 Annual Research Report
  • [Presentation] 自閉症の脳形態特徴 : VBM 研究2011

    • Author(s)
      齋藤有希, 山末英典, 八幡憲明, 夏堀龍暢, 青木悠太, 岩白訓周, 高野洋輔, 桑原斉, 川久保友紀, 五ノ井渉, 佐々木弘喜, 村上瑞穂, 桂正樹, 新橋靖真, 高尾英正, 国松聡, 阿部修, 松崎秀夫, 土屋賢治, 笠井清登
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-17
    • Related Report
      2013 Final Research Report
  • [Presentation] 統合失調症患者における作動記憶の下位項目の障害の神経関連 : fMRI 研究2011

    • Author(s)
      夏堀龍暢, 山末英典, 八幡憲明, 岩白訓周, 高野洋輔, 井上秀之, 五ノ井渉, 村上瑞穂, 桂正樹, 佐々木弘喜, 高尾英正, 国松聡, 阿部修, 笠井清登
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-17
    • Related Report
      2013 Final Research Report
  • [Presentation] 統合失調症患者における作動記憶の下位項目の障害の神経関連:fMRI研究2011

    • Author(s)
      夏堀龍暢、山末英典, 他12名2番目
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 自閉症の脳形態特徴:VBM研究2011

    • Author(s)
      齋藤有希、山末英典, 他18名2番目
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] 統合失調症発症前後における下前頭回の灰白質体積の変化2011

    • Author(s)
      岩白訓周, 山末英典, 管心, 夏堀龍暢, 高野洋輔, 井上秀之, 里村嘉弘, 小池進介, 八幡憲明, 村上瑞穂, 桂正樹, 五ノ井渉, 佐々木弘喜, 高尾英正, 阿部修, 笠井清登
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-16
    • Related Report
      2013 Final Research Report 2011 Annual Research Report
  • [Presentation] 自閉症における非定型な社会認知の神経基盤2011

    • Author(s)
      山末英典
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      横浜(招待講演)
    • Year and Date
      2011-09-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] 対人交渉の障害を生み出す脳神経基盤の同定と治療法開発の試み~男女差とオキシトシンに着目して~2011

    • Author(s)
      山末英典
    • Organizer
      第55回GHP研究会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-07-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脳障害から解く他者への協調や共感の物質機構、社会性の男女差2011

    • Author(s)
      山末英典
    • Organizer
      セルツーボディダイナミクスラボ主催第1回「身心一体科学研究会レクチャーシリーズ」
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-06-20
    • Related Report
      2011 Annual Research Report
  • [Presentation] Genetic social neuroimaging and autism2011

    • Author(s)
      Yamasue H
    • Organizer
      Genetic, cellular, and cognitive approaches to und erstanding social behavior-A joint Tamagawa University-Caltech Lecture Course, The 15^<th> annual meeting of the ASSC
    • Place of Presentation
      Kyoto, Japan(招待講演)
    • Year and Date
      2011-06-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Neuroanatomical basis of subclinical autistic trait2011

    • Author(s)
      Saito H, Yamasue H, Abe O, Suga M, Yahata N, Kawakubo Y, Kasai K, Yamada H, Aoki S
    • Organizer
      10th WFSBP Congres
    • Place of Presentation
      Prague, Czeck Republic
    • Year and Date
      2011-06-01
    • Related Report
      2013 Final Research Report
  • [Presentation] Gray matter volume changes of subregions in inferior frontal gyrus around the onset of psychosis2011

    • Author(s)
      Iwashiro N, Yamasue H, Suga M, Takano Y, Inoue H, Yahata N, Sasaki H, Takao H, Abe O, Kasai K
    • Organizer
      10th WFSBP Congres
    • Place of Presentation
      Prague, Czeck Republic
    • Year and Date
      2011-05-30
    • Related Report
      2013 Final Research Report
  • [Presentation] Neural basis of oxytocin effect on social deficits in autism spectrum disorders2011

    • Author(s)
      Yamasue H
    • Organizer
      10^<th> WFSBP Congres
    • Place of Presentation
      Prague, Czeck Republic(招待講演)
    • Year and Date
      2011-05-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] アスペルガー障害のNIRS 所見 : 言語流暢性課題を用いて2011

    • Author(s)
      岩波明, 岡島由佳, 太田晴久, 山田貴志, 谷将之, 橋本龍一郎, 金井智恵子, 渡部洋実, 川久保友紀, 山末英典, 加藤進昌
    • Organizer
      第33回生物学的精神医学会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-22
    • Related Report
      2013 Final Research Report
  • [Presentation] 自閉症の非定型な社会認知の脳神経基盤:子供から成人へ発達障害の予後、治療効果予測への取り組み2011

    • Author(s)
      山末英典
    • Organizer
      第33回生物学的精神医学会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-05-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 社会脳とは-発達的観点も含めて-2011

    • Author(s)
      山末英典
    • Organizer
      第21回太田ステージ研究会
    • Place of Presentation
      東京
    • Year and Date
      2011-01-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] 脳画像からみた広汎性発達障害の特徴2010

    • Author(s)
      山末英典
    • Organizer
      第一回金沢大学子どものこころサミット
    • Place of Presentation
      金沢
    • Year and Date
      2010-11-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] Association between the oxytocin receptor gene (OXTR) and amygdalar volume in healthy adults2010

    • Author(s)
      Inoue H, Yamasue H, Tochigi M , Abe O, Takei K, Suga M, Yamada H, Rogers MA, Aoki S, Liu X, Kawamura Y, Sasaki T, Kasai K
    • Organizer
      Neuroscience 2010, SfN's 40th annual meeting
    • Place of Presentation
      San Diego
    • Year and Date
      2010-11-16
    • Related Report
      2013 Final Research Report
  • [Presentation] Association between the oxytocin receptor gene (OXTR) and amygdalar volume in healthy adults.2010

    • Author(s)
      Inoue H, Yamasue H, 他11名2番目
    • Organizer
      Neuroscience 2010, SfN's 40th annual meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2010-11-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Reduced gray matter volumeof pars opercularis is associated with impaired social communication in high-functioning autism spectrum disorders2010

    • Author(s)
      Yamasue H, Yamasaki S, Abe O, Suga M, Yamada H, Inoue H, Kuwabara H, Kawakubo Y, Aoki S, Kano Y, Kato N, Kasai K
    • Organizer
      Neuroscience 2010, SfN's 40th annual meeting
    • Place of Presentation
      San Diego
    • Year and Date
      2010-11-14
    • Related Report
      2013 Final Research Report
  • [Presentation] Reduced gray matter volumeof pars opercularis is associated with impaired social communication in high-functioning autism spectrum disorders.2010

    • Author(s)
      Yamasue H, 他11名1番目
    • Organizer
      Neuroscience 2010, SfN's 40th annual meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2010-11-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 自閉症傾向の脳形態基盤2010

    • Author(s)
      齋藤有希, 山末英典, 阿部修, 管心, 八幡憲明, 川久保友紀, 山田晴耕, 青木茂樹, 笠井清登
    • Organizer
      第32回日本生物学的精神医学会
    • Place of Presentation
      北九州
    • Year and Date
      2010-10-09
    • Related Report
      2013 Final Research Report
  • [Presentation] ARMS(at risk mental state)群と初発統合失調症群における下前頭回の灰白質体積減少2010

    • Author(s)
      岩白訓周, 山末英典, 管心, 夏堀龍暢, 高野洋輔, 井上秀之, 里村嘉弘, 小池進介, 八幡憲明, 村上瑞穂, 桂正樹, 五ノ井渉, 佐々木弘喜, 高尾英正, 阿部修, 笠井清登
    • Organizer
      第32回日本生物学的精神医学会
    • Place of Presentation
      北九州
    • Year and Date
      2010-10-09
    • Related Report
      2013 Final Research Report
  • [Presentation] 統合失調症における単語の意味および語彙判断のプログラミング効果のfMRI 研究2010

    • Author(s)
      夏堀龍暢, 山末英典, 八幡憲明, 橋本龍一郎, 井上秀之, 高野洋輔, 岩白訓周, 武井邦夫, 五ノ井渉, 佐々木弘喜, 高尾英正, 阿部修, 笠井清登
    • Organizer
      第32回日本生物学的精神医学会
    • Place of Presentation
      北九州
    • Year and Date
      2010-10-09
    • Related Report
      2013 Final Research Report
  • [Presentation] 統合失調症における対人認知の障害の臨床病期による変化-Functional MRI研究2010

    • Author(s)
      高野洋輔、山末英典, 他2名2番目
    • Organizer
      第32回日本生物学的精神医学会
    • Place of Presentation
      北九州
    • Year and Date
      2010-10-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 統合失調症における臨床病期の進行に伴うグルタミン酸神経系の異常 : 3 テスラMRS を用いた検討2010

    • Author(s)
      井上秀之, 山末英典, 阿部修, 八幡憲明, 高野洋輔, 岩白訓周, 夏堀龍暢, 武井邦夫, 小池進介, 村上瑞穂, 桂正樹, 五ノ井渉, 佐々木弘喜, 高尾英正, 笠井清登
    • Organizer
      第32回日本生物学的精神医学会
    • Place of Presentation
      北九州
    • Year and Date
      2010-10-08
    • Related Report
      2013 Final Research Report
  • [Presentation] 広汎性発達障害成人の脳画像研究からわかること2010

    • Author(s)
      山末英典
    • Organizer
      国立精神・神経センター「第3回発達障害精神医療研修」
    • Place of Presentation
      東京
    • Year and Date
      2010-09-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 対人行動の障害の脳画像指標とその候補遺伝子との関連:社会的意思決定の生物学的基盤(1)-社会性・精神疾患・発達障害-2010

    • Author(s)
      山末英典
    • Organizer
      日本社会心理学会第51回大会
    • Place of Presentation
      東広島
    • Year and Date
      2010-09-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 共感の神経基盤における男女差の検討 : fMRI 研究2010

    • Author(s)
      高野洋輔, 山末英典, 八幡憲明, 橋本龍一郎, 五ノ井渉, 佐々木弘喜, 高尾英正, 夏堀龍暢, 岩白訓周, 井上秀之武井邦夫, 阿部修, 笠井清登
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-04
    • Related Report
      2013 Final Research Report
  • [Presentation] 対人行動の障害の神経基盤を求めて:対人社会系の神経科学:神経基盤の探索から自閉症の病態解明・治療法開発まで2010

    • Author(s)
      山末英典
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] オキシトシン受容体多型(OXTR)が扁桃体体積に与える影響2010

    • Author(s)
      井上秀之, 山末英典, 栃木衛, 阿部修, 武井邦夫, 管心, 山田晴耕, Rogers MA, 青木茂樹, 劉暁渓, 河村代志也, 佐々木司, 笠井清登
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Related Report
      2013 Final Research Report
  • [Presentation] 対人行動の障害の脳画像指標とその候補遺伝子との関連2010

    • Author(s)
      山末英典
    • Organizer
      Neuro 2010サテライトシンポジウム2010年度文部科学省関連脳科学研究事業合同ワークショップ「脳科学におけるヒト研究と動物研究のクロスオーバー」
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Blonanserin内服中に高度徐脈を呈した統合失調症の一例2010

    • Author(s)
      杉下和行, 音羽健司, 蒲谷洋平, 荒木剛, 山末英典, 笠井清登
    • Organizer
      第106回日本精神神経学会学術総会
    • Place of Presentation
      広島
    • Related Report
      2013 Final Research Report
  • [Presentation] Clinical trails utilizing bio-markers as outcome measures to develop therapeutics for core symptoms of autism spectrum disorders

    • Author(s)
      山末英典
    • Organizer
      脳科学総合研究センター主催フォーラム
    • Place of Presentation
      理化学研究所(和光)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Neural basis of recovery of autistic socio-communicative deficits induced by intranasal oxytocin

    • Author(s)
      Hidenori Yamasue
    • Organizer
      International symposium - New Horizon on Neuroscience of Development and Developmental Disorders -
    • Place of Presentation
      東北大学加齢医学研究所
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 自閉症スペクトラム障害の脳画像解析から治療開発へ

    • Author(s)
      山末英典
    • Organizer
      「発達障害研究の最前線」、東京医科歯科大学難治疾患研究所・国立環境研究所共催シンポジウム
    • Place of Presentation
      東京医科歯科大学
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] ASD中核症状治療薬の開発~オキシトシン点鼻剤の臨床試験~

    • Author(s)
      山末英典
    • Organizer
      第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会
    • Place of Presentation
      沖縄
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Neurogenetic correlates of autistic social dysfunction

    • Author(s)
      Hidenori Yamasue
    • Organizer
      WFSBP Congress 2013 11th World Congress of Biological Psychiatry
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] “Neural correlates of autistic social deficits and its association with candidate genotypes”, Symposium “Multimodal neuroimaging studies in autism: Neuroanatomical, chemical, and genetic aspects of social cognition deficits”

    • Author(s)
      Yamasue H
    • Organizer
      Neuroscience 2012 the 35th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Nagoya, Japan
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] “Neurobiological correlatesof autistic social behavior” APSN/JSN-JSBP Joint Symposium “広汎性発達障害の過去、現在、未来”

    • Author(s)
      Yamasue H
    • Organizer
      31th Annual Meeting of Japanese Society of Biological Psychiatry
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] “OXTR and neuroanatomy in limbic and paralimbic brain regions: implicatin s for autism research and treatment”, Minisymposium “Integrative Approaches Utilizing Oxytocin To Enhance Prosocial Behavior: From Animal and Human Social Behavior to Autistic Social Dysfunction”

    • Author(s)
      Yamasue H
    • Organizer
      Neuroscience 2012, SfN's 42nd annual meeting
    • Place of Presentation
      New Orleans, USA
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Presentation] 「性差からみた自閉症スペクトラム障害」、シンポジウム脳科学から見た性差医学・医療

    • Author(s)
      山末英典
    • Organizer
      第6回日本性差医学・医療学会学術集会
    • Place of Presentation
      宮城(仙台)
    • Related Report
      2012 Annual Research Report
    • Invited
  • [Book] ブレインサイエンスレビュー2012, 多面的脳MRI による対人行動の障害の研究2012

    • Author(s)
      山末英典
    • Publisher
      クバプロ
    • Related Report
      2013 Final Research Report
  • [Book] 多面的脳MRIによる対人行動の障害の研究.ブレインサイエンスレビュー20122012

    • Author(s)
      山末英典
    • Publisher
      クバプロ
    • Related Report
      2011 Annual Research Report
  • [Book] アスペハート, 特集 自閉症はどこまでわかってきたのか-生物学的精神医学研究と支援をつなげる, 脳の機能・形態の問題として明らかになったこと-MRI 研究が明らかにしたこと2011

    • Author(s)
      山末英典
    • Publisher
      アスペ・ベルデの会
    • Related Report
      2013 Final Research Report
  • [Book] 精神医学キーワード事典, 12章脳画像, 脳生理学, 208「自閉症スペクトラム障害の脳画像研究」2011

    • Author(s)
      山末英典
    • Publisher
      中山書店
    • Related Report
      2013 Final Research Report
  • [Book] 精神医学キーワード事典, 12章脳画像, 脳生理学, 206「初期統合失調症の脳画像」2011

    • Author(s)
      山末英典
    • Publisher
      中山書店
    • Related Report
      2013 Final Research Report
  • [Book] 『精神科 研修ノート』 第2章 精神科研修でマスターすべきこと, B 脳科学からのアプローチ, 2.脳と精神障害の関連2011

    • Author(s)
      山末英典
    • Publisher
      診断と治療社
    • Related Report
      2013 Final Research Report
  • [Book] 脳と精神障害の関連.精神科研修ノート2011

    • Author(s)
      山末英典
    • Publisher
      診断と治療社
    • Related Report
      2011 Annual Research Report
  • [Book] 初期統合失調症の脳画像.精神医学キーワード事典2011

    • Author(s)
      山末英典
    • Publisher
      中山書店
    • Related Report
      2011 Annual Research Report
  • [Book] 特集自閉症はどこまでわかってきたのか-生物学的精神医学研究と支援をつなげる、脳の機能・形態の問題として明らかになったこと-MRI研究が明らかにしたこと、アスペハートvol.282011

    • Author(s)
      山末英典
    • Publisher
      アスペ・エルデの会
    • Related Report
      2011 Annual Research Report
  • [Book] Rutter's Child and Adolescent Psychiatry」Chapter 11 What Can We Learn from Structural and Functional Brain Imaging?、邦題「(仮)児童青年精神医学」2011

    • Author(s)
      山末英典
    • Publisher
      明石書店(印刷中)(刊行確定)
    • Related Report
      2010 Annual Research Report
  • [Book] 『専門医のための精神科臨床リュミエール』21巻 前頭葉でわかる精神疾患の臨床, III. 精神疾患における前頭葉の構造と機能 4. PTSD2010

    • Author(s)
      山末英典
    • Publisher
      中山書店
    • Related Report
      2013 Final Research Report
  • [Book] 『専門医のための精神科臨床リュミエール』19巻 広汎性発達障害-自閉症へのアプローチ, II. 理論編 5. 広汎性発達障害の画像研究2010

    • Author(s)
      山末英典
    • Publisher
      中山書店
    • Related Report
      2013 Final Research Report
  • [Book] 『専門医のための精神科臨床リュミエール』16巻 脳科学エッセンシャル-精神疾患の生物学的理解のために, III. 中枢神経の構造と機能 I.辺縁系と視床下部, 2.帯状皮質と情動2010

    • Author(s)
      山末英典
    • Publisher
      中山書店
    • Related Report
      2013 Final Research Report
  • [Book] 『専門医のための精神科臨床リュミエール』19巻広汎性発達障害-自閉症へのアプローチ、II.理論編5.広汎性発達障害の画像研究2010

    • Author(s)
      山末英典
    • Total Pages
      7
    • Publisher
      中山書店
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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