| Budget Amount *help |
¥22,360,000 (Direct Cost: ¥17,200,000、Indirect Cost: ¥5,160,000)
Fiscal Year 2012: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2011: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2010: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
|
|---|
| Research Abstract |
iPS cells can be generated from somatic cells by forced expression of defined exogenous factors. We found that the gingiva, which is often resected during general dental treatments and treated as biomedical waste, is a promising source of iPS cells. These iPS cells were capable of osteogenic differentiation, which could be greatly enhanced by some small molecules. The generation of iPS cells from the gingiva offers a promising method for the facile production of iPS cells by dentists, which represent an important step toward the development of novel alveolar bone regeneration technology.
|
