Development of algorithms for genome sequencing using next-generationDNA sequencers

Research Project

Project/Area Number	22700307
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Bioinformatics/Life informatics
Research Institution	The University of Tokyo
Principal Investigator	KASAHARA Masahiro 東京大学, 大学院・新領域創成科学研究科, 講師 (60376605)
Project Period (FY)	2010 – 2012
Project Status	Completed (Fiscal Year 2012)
Budget Amount *help	¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000) Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000) Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000) Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords	ゲノム / アルゴリズム / ゲノムアセンブリ / 遺伝学的地図
Research Abstract	Genome sequencing using so-called next-generation DNA sequencers often results in rather fragmented sequences, and the positions of the fragmented sequences on chromosomes are usually unknown. We developed a system/algorithm that constructs a genetic map in a short time with less labor using next-generation DNA sequencers. Genetic maps generated by our algorithm can arrange fragmented sequences on chromosomes.

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