Analysis of dendrite specific Rab protein in neuron
| Project/Area Number |
22700324
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Neuroscience in general
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
MORI Yasunori 東北大学, 大学院・生命科学研究科, 助教 (80443042)
|
|---|
| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
|
|---|
| Keywords | 分子 / 細胞神経科学 / 神経 / 樹状突起 / 極性 / 小胞輸送 / Rab |
|---|
| Research Abstract |
It has been reported that several members of the Rab family small GTPases, which are key mediators of membrane trafficking, regulate axon-specific trafficking events, but little has been elucidated regarding the molecular mechanisms that underlie dendrite-specific membrane trafficking. We showed that Rab17 regulates dendritic morphogenesis and postsynaptic development in mouse hippocampal neurons.
|
Report
(3 results)
Research Products
(13 results)
-
-
-
-
-
[Journal Article] Role of the polybasic sequence in the Doc2alpha C2B domain in dense-core vesicle exocytosis in PC12 cells.2010
Author(s)
Sato, M, Mori, Y., Matsui, T., Aoki, R., Ohya, M., Yanagihara, Y., Fukuda, M. and Tuboi, T
-
Journal Title
J. Neurochem
Volume: 114
Pages: 171-181
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
