Research Project
Grant-in-Aid for Young Scientists (B)
Compulsive-repetitive behaviors are common core symptom that are shared between autism spectrum disorders and obsessive-compulsive spectrum disorders. The underlying pathogenic mechanisms of compulsive-repetitive behaviors are largely unknown. Here we show glutamate transporter conditional knockout mice exhibit compulsive-repetitive behaviors due to increased glutamate neural transmission. These findings demonstrate glutamatergic hyperactivity is important for pathogenesis of compulsive-repetitive behaviors.
All 2011 2010 Other
All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (7 results) Book (8 results)
Plos One
Volume: (in press)
