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Regulation of retinotopy by Wnt signaling in the higher order visual center

Research Project

Project/Area Number 22700333
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Neuroscience in general
Research InstitutionKanazawa University

Principal Investigator

SATO Makoto  金沢大学, フロンティアサイエンス機構, 特任准教授 (30345235)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords脳・神経 / 神経科学 / 神経回路 / 視覚系 / Wnt
Research Abstract

When visual information received in the retina is transmitted to the brain, the spatial order of retinal axons is preserved in the spatial order of their targets. Such retinotopic projections are observed throughout the visual system. However, molecular mechanisms that establish the retinotopy in the higher order visual center remain elusive. In this study, we focused on the roles of Wnt family proteins in the fly visual center and revealed key mechanisms that form the retinotopy in the higher order visual center.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (14 results)

All 2012 2011 2010 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (6 results) Book (1 results) Remarks (2 results)

  • [Journal Article] Concentric zones, cell migration and neuronal circuits in the Drosophila visual center2011

    • Author(s)
      Hasegawa, E., Kitada, Y., Kaido, M., Takayama, R., Awasaki, T., Tabata, T. and Sato, M.
    • Journal Title

      Development

      Volume: 138 Issue: 5 Pages: 983-993

    • DOI

      10.1242/dev.058370

    • NAID

      120002924884

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Wnt5/Planar cell polarity pathway regulates axonal development of the Drosophila mushroom body neuron2011

    • Author(s)
      Shimizu, K., Sato, M. and Tabata, T.
    • Journal Title

      Journal of Neuroscience

      Volume: 31 Issue: 13 Pages: 4944-4954

    • DOI

      10.1523/jneurosci.0154-11.2011

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fat/Hippo pathway regulates the progress of neural differentiation signaling in the Drosophila optic lob2011

    • Author(s)
      Kawamori, H., Tai, M. Sato, M., Yasugi, T. and Tabata, T.
    • Journal Title

      Development Growth and Differentiation

      Volume: 53 Issue: 5 Pages: 653-667

    • DOI

      10.1111/j.1440-169x.2011.01279.x

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Robustness of the Dpp morphogen activity gradient depends on negative feedback regulation by the inhibitory Smad2011

    • Author(s)
      Ogiso, Y., Tsuneizumi, K., Masuda, N., Sato, M. and Tabata, T.
    • Journal Title

      Development Growth and Differentiation

      Volume: 53 Issue: 5 Pages: 668-678

    • DOI

      10.1111/j.1440-169x.2011.01274.x

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Concentric zones, cell migration and neuronal circuits in the Drosophila visual center2011

    • Author(s)
      Hasegawa, E.
    • Journal Title

      developmen

      Volume: 138 Pages: 983-993

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Molecular basis of the production of neuronal diversity in the Drosphipha visual center2012

    • Author(s)
      Suzuki, T., Kaido, M., Takayama, R. and Sato, M.
    • Organizer
      Annual Drosophila Research Conference
    • Place of Presentation
      Sheraton Chicago Hotel & Towers(USA)
    • Related Report
      2011 Final Research Report
  • [Presentation] Molecular basis of the production of neuronal diversity in the Drosphipha visual center2012

    • Author(s)
      Suzuki, T., Kaido, M., Takayama, R., Sato, M.
    • Organizer
      Annual Drosophila Research Conference
    • Place of Presentation
      米国シカゴ
    • Related Report
      2011 Annual Research Report
  • [Presentation] ショウジョウバエ視覚中枢において神経細胞の多様性を産み出す分子機構の解析2011

    • Author(s)
      鈴木匠、海道雅子、高山理恵、佐藤純
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-12-13
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Brain-specific-homeobox is required for the specification of neuronal types in the optic lobe2011

    • Author(s)
      Hasegawa, E., Kaido, M., Takayama, R., Tabata, T. and Sato, M
    • Organizer
      Cold Spring Harbor Laboratory Meeting on Neurobiology of Drosophila
    • Place of Presentation
      コールドスプリングハーバー研究所(USA)
    • Related Report
      2011 Final Research Report
  • [Presentation] Brain-specific-homeobox is required for the specification of neuronal types in the optic lobe2011

    • Author(s)
      Hasegawa, E., Kaido, M., Takayama, R., Tabata, T., Sato, M.
    • Organizer
      Cold Spring Harbor Laboratory Meeting on Neurobiology of Drosophila
    • Place of Presentation
      米国コールドスプリングハーバー
    • Related Report
      2011 Annual Research Report
  • [Presentation] Concentric zones, cell migration and neuronal circuits in the Drosophila visual center2010

    • Author(s)
      Sato, M.
    • Organizer
      Gordon Research Conference, Visual System Development
    • Place of Presentation
      Il Ciocco Hotel and Resort(イタリア)
    • Year and Date
      2010-05-24
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Book] ブレインサイエンス・レビュー20102010

    • Author(s)
      佐藤純
    • Publisher
      クバプロ
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Remarks]

    • URL

      http://fsosato.w3.kanazawa-u.ac.jp/index.html

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://fsosato.w3.kanazawa-u.ac.jp/index.html

    • Related Report
      2011 Annual Research Report

URL: 

Published: 2010-08-23   Modified: 2016-04-21  

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