Distribution of dopamine receptors in the marmoset brain : a PET study
| Project/Area Number |
22700340
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neuroscience in general
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| Research Institution | Kobe University |
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Principal Investigator |
TSUJIMOTO Satoshi 神戸大学, 大学院・人間発達環境学研究科, 准教授 (20539241)
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| Research Collaborator |
MINAMIMOTO Takafumi 独立行政法人放射線医学総合研究所, チームリーダー (23011006)
NAGAI Yuji 独立行政法人放射線医学総合研究所, 研究員 (20415409)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 認知神経科学 / 霊長類 / ドーパミン / サル / 分子イメージング / マーモセット / 大脳皮質 / 前頭前野 / モノアミン / 受容体 / PET |
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| Research Abstract |
We assessed the distribution of dopamine receptors in the marmoset brain with a PET using radioactive ligand. We observed high binding potential of dopamine D1 and D2 receptors in the striatum. We also evaluated the biding potential in the cerebral cortex, and confirmed variations across cerebral areas. This study established the method for quantitative evaluation of dopamine in the marmoset brain, and provided the data to construct a database.
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Report
(3 results)
Research Products
(22 results)
