| Project/Area Number |
22700365
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | University of Fukui |
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Principal Investigator |
|
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| Project Period (FY) |
2010 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 神経回路網 / 聴覚神経回路 / 聴覚 / 局所神経回路 / ウイルスベクター / GABA / glutamate / 聴覚系 / グルタミン酸 / 聴覚系神経回路 |
|---|
| Research Abstract |
Information of sound is analyzed in several auditory nuclei in lower brainstem, and re-integrated in the inferior colliculus in the midbrain. Detailed morphological basis on the integration of sound information, however, is poorly known. Large GABAergic neurons, which composeapproximately 10% of inferior collicular neurons and project to the thalamus, receive dense excitatory axosomatic inputs. In this study, we showed that the axosomatic inputs originated from almost all lower auditory nuclei as well as local neurons, suggesting that large GABAergic neurons integrate auditory information. We also have developed viral tracers which are optimal for the study on detailed dendritic morphology of large GABAergic neurons.
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