Structure and function of the neural circuit processing whiskersensation : focusing on cortical layer 4

• Project/Area Number: 22700368
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Nerve anatomy/Neuropathology
• Research Institution: Kyoto University
• Principal Investigator: FURUTA Takahiro 京都大学, 医学研究科, 助教 (60314184)
• Project Period (FY): 2010 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: 神経回路網 / ヒゲ感覚システム / 大脳皮質 / barrel / 視床 / 方向選択性マップ / バレル構造

Research Abstract

Response properties of thalamic neurons to whisker stimulation in rats. Furthermore, in cortical layer 4 arborization of axons derived from the recorded neuron was reconstructed. By analyzing the correlation between the response properties and the axonal arborization in each neuron, we revealed that thalamocortical input consists of two overlapping angular tuning maps.

Research Products

• [Journal Article] Parvalbuminproducing cortical Interneurons receive inhibitory inputs on Proximal portions and cortical excitatory inputs on distal dendrites. (2012)
  • Author(s): Kameda H, Hioki H, Tanaka YH, Tanaka T, Sohn J, Sonomura T, Furuta T,Fujiyama F, Kaneko T
  • Journal Title: European Journal of Neuroscience Volume: vol. 35 (no. 6) Issue: 6 Pages: 834-854
  • DOI: 10.1111/j.1460-9568.2012.08027.x
  • Peer Reviewed
• [Journal Article] Morphological analysis of thalamocortical axon fibers of rat posterior thalamic nuclei: A single neuron tracing study with viral vectors (2012)
  • Author(s): Ohno S, Kuramoto E, Furuta T, Hioki,H Tanaka YR, Fujiyama F, Sonomura T,Uemura M, Sugiyama K, Kaneko T
  • Journal Title: Cerebral Cortex Volume: vol. 22 Issue: 12 Pages: 2840-2857
  • DOI: 10.1093/cercor/bhr356
  • NAID: 120005243652
  • Peer Reviewed
• [Journal Article] Morphological analysis of thalamocorticalaxon fibers of rat posterior thalamic nuclei : A single neuron tracing study with viral vectors (2011)
  • Author(s): Ohno S, Kuramoto E, Furuta T, Hioki H, Tanaka Y, Fujiyama F, Sonomura T, Uemura M, Sugiyama K, Kaneko T
  • Journal Title: Cereb Cortex Volume: (in press)
  • Peer Reviewed
• [Journal Article] Local connections of excitatory neurons to corticothalamic neurons in the rat barrel cortex. (2011)
  • Author(s): Tanaka YR, Tanaka YH, Konno M, Fujiyama F, Sonomura T, Okamoto-Furuta K, Kameda H, Hioki H, Furuta T, Nakamura KC, and Kaneko T
  • Journal Title: J Neurosci Volume: (in press)
  • NAID: 120004397861
  • Peer Reviewed
• [Journal Article] Local connections of layer 5 GABAergic interneurons to corticospinal neurons (2011)
  • Author(s): Tanaka YH, Tanaka YR, Fujiyama F, Furuta T, Yanagawa Y, Kaneko T
  • Journal Title: Front Neural Circuits Volume: 5(12)
  • URL: http://dx.doi.org/10.3389/fncir.2011.00012
  • Peer Reviewed
• [Journal Article] Dynorphin is expressed primarily by GABAergic neurons that contain galanin in the rat dorsal horn (2011)
  • Author(s): Sardella TC, Polgar E, Garzillo F, Furuta T, Kaneko T, Watanabe M, Todd AJ
  • Journal Title: Mol Pain Volume: 7(76)
  • URL: http://dx.doi.org/10.1186/1744-8069-7-76
  • Peer Reviewed
• [Journal Article] Anisotropic distribution of thalamocortical boutons in barrels (2011)
  • Author(s): Furuta T, Deschenes M, Kaneko T
  • Journal Title: J Neurosci Volume: 31(17) Pages: 6432-9
  • URL: http://dx.doi.org/10.1523/JNEUROSCI.6154-10.2011
  • Peer Reviewed
• [Journal Article] Expression of Gap Junction Protein Connexin 36 in Multiple Subtypes of GABAergic Neurons in Adult Rat Somatosensory Cortex (2011)
  • Author(s): Ma YF, Hioki H, Konno M, Pan SX, Nakamura H, Nakamura KC, Furuta T, LiJ-L, Kaneko T
  • Journal Title: Cereb Cortex Volume: 21(11) Pages: 2639-49
  • NAID: 120004247261
  • URL: http://dx.doi.org/10.1093/cercor/bhr051
  • Peer Reviewed
• [Journal Article] Patterns of axonal collateralization of single layer V cortical projection neurons in the rat presubiculum (2011)
  • Author(s): Honda Y, Furuta T, Kaneko T, Shibata H, Sasaki H
  • Journal Title: J Comp Neurol Volume: 519(7) Pages: 1395-412
  • URL: http://dx.doi.org/10.1002/cne.22578
  • Peer Reviewed
• [Journal Article] Exclusive and common targets of neostriatofugal projections of rat striosomeneurons : a single neuron-tracing study using a viral vector (2011)
  • Author(s): Fujiyama F, Sohn J, Nakano T, Furuta T, Nakamura KC, Matsuda W, Kaneko T.
  • Journal Title: Eur J Neurosci Volume: 33(4) Pages: 668-77
  • URL: http://dx.doi.org/10.1111/j.1460-9568.2010.07564.x
  • Peer Reviewed
• [Journal Article] Local connections of excitatory neurons to corticothalamic neurons in the rat barrel cortex. (2011)
  • Author(s): Tanaka YR, Tanaka YH, Konno M,Fujiyama F, Sonomura T, Okamoto-FurutaK, Kameda H, Hioki H, Furuta T,Nakamura KC, Kaneko T
  • Journal Title: Journal of Neuroscience Volume: vol. 31 (no. 50) Issue: 50 Pages: 18223-28236
  • DOI: 10.1523/jneurosci.3139-11.2011
  • NAID: 120004397861
  • Peer Reviewed
• [Journal Article] Dynorphin is expressed primarily by GABAergic neurons that contain galanin in the rat dorsal horn (2011)
  • Author(s): Sardella, T.C.P.; Polgar, E.; Garzillo, F., et al
  • Journal Title: Molecular Pain Volume: 7(on line) Pages: 76-76
  • DOI: 10.1186/1744-8069-7-76
  • Peer Reviewed
• [Journal Article] Anisotropic distribution of thalamocortical buutons in barrels. (2011)
  • Author(s): Furuta T, Deschenes M, Kaneko T
  • Journal Title: Journal of Neuroscience Volume: (In press)
  • Peer Reviewed
• [Journal Article] Exclusive and common targets of neostriatofugal projections of rat striosome neurons : A single neuron-tracing study using a viral vector. (2011)
  • Author(s): Fujiyama F, Sohn J, Nakano T, Furuta T, Nakamura KC, Matsuda W, Kaneko T
  • Journal Title: European Journal of Neuroscience Volume: (In press)
  • Peer Reviewed
• [Journal Article] Expression of Gap Junction Protein Connexin36 in Multiple Subtypes of GABAergic Neurons in Adult Rat Somatosensory Cortex. (2011)
  • Author(s): Ma YF, Hioki H, Konno M, Pan SX, Nakamura H, Nakamura KC, Furuta T, Li J-L, Kaneko T
  • Journal Title: Cereb Cortex Volume: (In press)
  • NAID: 120004247261
  • Peer Reviewed
• [Presentation] Morphological analysis of axon collaterals derived from single corticospinal neurons in subcortical structures (2012)
  • Author(s): 古田貴寛
  • Organizer: 第117回日本解剖学全国学術集会
  • Place of Presentation: 山梨大学
  • Year and Date: 2012-03-27
• [Presentation] Morphological analysis of axon collaterals derived from single corticospinal neurons in subcortical structures (2012)
  • Author(s): Furuta T, Kaneko T
  • Organizer: 第116回日本解剖学会学術集会
  • Place of Presentation: 甲府大学
  • Year and Date: 2012-03-27
• [Presentation] 皮質脊髄路ニューロンの軸索側枝を単一ニューロンレベルで形態学的に解析する (2011)
  • Author(s): 古田貴寛
  • Organizer: 第34回日本神経科学大会
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2011-09-16
• [Presentation] Morphological analysis of axon collaterals derived from single corticospinal neurons in subcortical structures : anatomical evidence for "efference copy" (2011)
  • Author(s): Furuta T, Kaneko T
  • Organizer: 第34回日本神経科学大会
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2011-09-16
• [Presentation] 三叉神経核群中間亜核のヒゲ感覚ニューロンに対する大脳皮質由来の制御 (2010)
  • Author(s): 古田貴寛
  • Organizer: 第33回に本神経科学大会
  • Place of Presentation: 神戸コンベンションセンター
  • Year and Date: 2010-09-02
• [Presentation] 三叉神経核群中間亜核のヒゲ感覚ニューロンに対する大脳皮質由来の制御 (2010)
  • Author(s): 古田貴寛、Urbain N, 金子武嗣、Deschenes M
  • Organizer: Neuro2010
  • Place of Presentation: 神戸コンベンションセンター
  • Year and Date: 2010-09-02
• [Book] ブレインサイエンスレビュー2012 (2012)
  • Author(s): 古田貴寛
  • Publisher: クバプロ
• [Book] ブレインサイエンスレビュー2012 (2012)
  • Author(s): 古田貴寛, 他共著
  • Total Pages: 300
  • Publisher: クバプロ
• [Remarks]
  • URL: http://www.mbs.med.kyoto-u.ac.jp/
• [Remarks]
  • URL: http://www.mbs.raed.kyoto-u.ac.jp/
• [Remarks]
  • URL: http://www.mbs.med.kyoto-u.ac.jp/