Research Project
Grant-in-Aid for Young Scientists (B)
IL-1 receptor accessory protein-like 1(IL1RAPL1) is responsible for X-linked mental retardation and autism. Expression of IL1RAPL1 in cultured cortical neurons enhanced synapse formation while knockdown of IL1RAPL1 suppressed synaptogenesis. Postsynaptic IL1RAPL1 mediated excitatory synapse formation through trans-synaptic interaction with presynaptic protein tyrosine phosphatase(PTP)δ.
All 2012 2011 2010 Other
All Journal Article (12 results) (of which Peer Reviewed: 12 results) Presentation (49 results) Remarks (2 results)
J.Neurochem.
Volume: (E-pub on 24 Jan 2012) Issue: 5 Pages: 705-716
10.1111/j.1471-4159.2011.07631.x
J.Neurosci.
Volume: 32 Issue: 13 Pages: 4688-4701
10.1523/jneurosci.5584-11.2012
J Neurosci
Volume: 32 Issue: 8 Pages: 2588-2600
10.1523/jneurosci.4637-11.2012
J. Neurochem
Volume: 119 Issue: 3 Pages: 532-543
10.1111/j.1471-4159.2011.07411.x
Volume: 31 Issue: 38 Pages: 13485-13499
10.1523/jneurosci.2136-11.2011
Biochemical and Biophysical Research Communications
Volume: 406(6) Issue: 4 Pages: 627-632
10.1016/j.bbrc.2011.02.108
Neurosci. Lett.
Volume: 488 Issue: 2 Pages: 215-220
10.1016/j.neulet.2010.11.032
Journal of Neuroscience
Volume: 31 Pages: 13485-13499
Biochemcal and Biophysical Research Communications
Volume: 406 Pages: 627-632
Neuroscience Letters
Volume: 488 Pages: 215-220
Cell
Volume: 141 Issue: 6 Pages: 1068-1079
10.1016/j.cell.2010.04.035
Volume: 141 Pages: 1068-1079
http://www.pharmacol2.m.u-tokyo.ac.jp/