| Project/Area Number |
22700446
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Fusional social brain science
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| Research Institution | Waseda University (2011)
The Institute of Physical and Chemical Research (2010) |
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Principal Investigator |
TOBARI Yasuko 早稲田大学, 教育・総合科学学術院, 助手 (90453919)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 動機付け / 情動 / 神経ペプチド / 神経内分泌学 / ペプチドホルモン / RFアミドペプチド / 社会性行動 / 中脳ドーパミン系 / モチベーション / 鳴禽類 / 視床下部 / RFamideペプチド / 本能行動 / 生殖内分泌系 |
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| Research Abstract |
The ventral tegmental area(VTA) contains dopamine neurons that are important in modulating motivated behavior, addiction, and reward. Here, we show that VTA dopamine neurons express GnIH receptor mRNA and receive synaptic input that contains gonadotropin-inhibitory hormone(GnIH). Furthermore, we examined changes in the activity of GnIH neurons in the brain of male following a view of and sexual interaction with a female. The presence of female seems to result in a change in diencephalic GnIH mRNA levels of male. These data support a new role for central GnIH with possible implications for regulation of sexual motivation
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