| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2012: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Research Abstract |
In this study, we carried out immunotherapy with photodynamic vaccination for infection disease in vitro and in vivo. The polyion complex micelle which made with PEG-pLLys(12-46) and DPc was incorporated to lysosome within four hours. Additionally, this micelle induced CD8 positive and IFNg secreted T cells after photo irradiation with laser. However, this reaction cannot detect the memory T cells. In future, we need to verification of immunological memory reaction in this immunotherapy.
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