Design of artificial niche derived from functional proteins
| Project/Area Number |
22700468
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | University of Toyama (2011-2012)
Kyoto University (2010) |
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Principal Investigator |
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 人工臓器工学 / 再生医工学 / キメラタンパク質 / 幹細胞 / 人工ニッシェ / 細胞移植用材料 / パーキンソン病 / 幹細胞移植医療 / 分化誘導 / ドーパミン神経 / 再生医療 / キメラ蛋白質 / 移植用材料 / 幹細胞移植治療 |
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| Research Abstract |
I have been carried out the research for designing novel functional hydrogel incorporated with proteins for the protection and differentiation of transplanted cells. This hydrogel overcome the problems of “cell death with receiving damage from inflammatory response and an absence of adhesive scaffold” and “the defection of ability for strictly regulating differentiation in the host tissue”. In this study, I designed a collagen-based hydrogel possessing an ability for protection of transplanted cells and a biodegradable microparticles for strictly regulating the differentiation into dopaminergic neuron
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Report
(4 results)
Research Products
(39 results)
