| Project/Area Number |
22700491
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Osaka University |
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Principal Investigator |
FUJII Fumihiko 大阪大学, 免疫学フロンティア研究センター, 特任助教 (40374657)
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| Project Period (FY) |
2010 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | ナノマテリアル / 免疫応答 / バイオイメージング |
|---|
| Research Abstract |
To visualize the dynamics of nanomaterials and immune responses in tissue, we have developed two techniques described below. 1. In addition to three dimensional motion of nanomaterials, their rotational motion is also crucial to reveal their dynamics in tissue. Thus, we synthesized polarized-semiconductor nanocrystals and demonstrated rotational single particle tracking of the nanomaterial. 2. Semiconductor nanocristals induced apoptosis in a specific condition. Furthermore, we confirmed that macrophages phagocyte the apoptotic cells.
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