Effective resistance exercise method for muscle atrophy based on a cell biology
| Project/Area Number |
22700555
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Nagoya Gakuin University |
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Principal Investigator |
ITOH Yuta 名古屋学院大学, リハビリテーション学部, 助手 (30454383)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 筋萎縮 / 筋力増強運動 / 細胞生物学 / リハビリテーション科学 / 運動療法学 / 動物 / 骨・筋肉 / 筋肉生理学 / リハビリテーション / 生理学 / 細胞・組織 / マウス |
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| Research Abstract |
Recovery from skeletal muscle atrophy by resistance exercise was examined in mice. After tail suspention, the animals were subjected to resistance exercise(RE). The myofiber thickness of soleus muscle of the mice with RE was significantly greater than that of non RE group, and was not significantly different from normal mice. Intriguingly, the number of myonuclei of the mice with RE was 1.5 times greater than that of non RE mice. We found that the newly-acquired myonuclei were increased within a few days after the onset of RE, suggesting that satellite cells proliferated rapidly after the onset of RE and fused to the myofibers.
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Report
(3 results)
Research Products
(11 results)
