Effects of voluntary exercise during early postnatal periods on the development of emotion regulation
| Project/Area Number |
22700591
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Physical education
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| Research Institution | Yamaguchi University |
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Principal Investigator |
ISHIKAWA Junko 山口大学, 大学院・医学系研究科, 助教 (30570808)
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 幼少期運動 / 前頭前野 / 発達 / 運動 / 情動 / セロトニン |
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| Research Abstract |
The present study investigated the effect of voluntary exercise during early postnatal period on the abnormal behaviors and developmental disruption of prefrontal cortex induced by early weaning(EW), which is widely used as early life stress. EW caused hyper locomotor activity in the novelty in juvenile and adult animals, whereas this adverse effect of EW was not observed in adult animals which have been exercised voluntary began simultaneously with EW until normal weaning period. In addition, voluntary exercise after EW until normal weaning period prevented disruption of monoaminergic axon development and morphological changes of the pyramidal cell in the prefrontal cortex induced by EW. The present study clearly demonstrated the beneficial effects of voluntary exercise during early postnatal period.
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Report
(3 results)
Research Products
(4 results)
