Effect of oxygen carrier(myoglobin) expression on mitochondrial activity
| Project/Area Number |
22700648
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Sports science
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| Research Institution | Nagoya Institute of Technology |
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Principal Investigator |
HANAI Yoshiteru 名古屋工業大学, 大学院・工学研究科, 教授 (50360730)
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| Co-Investigator(Renkei-kenkyūsha) |
MASUDA Kazumi 金沢大学, 大学院・自然科学研究科, 教授 (50323283)
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| Research Collaborator |
MATSUBARA Yuki 名古屋工業大学, 大学院・工学研究科, 大学院生
MASUDA Yuki 名古屋工業大学, 大学院・工学研究科, 大学院生
ITOH Yuka 名古屋工業大学, 大学生
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| Project Period (FY) |
2010 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2011: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2010: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | ミオグロビン / 骨格筋 / 培養骨格筋細胞 / ミトコンドリア |
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| Research Abstract |
The purpose of the present study was to investigate the relationships between muscular oxygen carrier, myoglobin, and the main target for oxygen delivery, mitochondria. Among various rat skeletal muscles, those differ with contractile property or oxidative capacity, the expression levels of myoglobin and mitochondriarelated proteins showed positive relationships. In the cell culture model, we could not establish an effective experimental model for further analysis.
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Report
(3 results)
Research Products
(2 results)
