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Metabolism of dietary Mg during exercise and preventive effect of Mg on chronic disease

Research Project

Project/Area Number 22700654
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Sports science
Research InstitutionJosai International University

Principal Investigator

SAKAI Kensuke  城西国際大学, 薬学部, 准教授 (70406784)

Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsスポーツ栄養学 / 栄養学 / 食品 / 生理学 / 運動
Research Abstract

Apparent Mg absorption in exercised rats was higher than that in sedentary rats. In addition, decrease in serum Mg level and increase in amount of Mg and expression of TRPM7 protein in skeletal muscle were observed in exercised rats. Moreover, there are positive relationship between amount of skeletal Mg level and gluco-regulatory enzymes(PFK and PK). These results suggested exercise might induce Mg influx into skeletal muscle. On the other hand, increase in amount of dietary Mg improved the expression of TRPM7 levels, but did not affect the amount of skeletal Mg levels. This result confused our hypothesis, and the mechanism of Mg metabolism during exercise was still unclear. Now, we examine whether metabolic acidosis induced by exercise affect Mg influx and distribution.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (2 results)

All 2012

All Presentation (2 results)

  • [Presentation] 運動負荷ラットにおけるマグネシウム代謝と骨格筋TRPM7の発現に関する研究2012

    • Author(s)
      須藤利哉、柴田龍一、首藤恵理子、太田篤胤、酒井健介
    • Organizer
      第67回日本体力医学会
    • Place of Presentation
      長良川国際会議場(発表予定)
    • Related Report
      2011 Final Research Report
  • [Presentation] マグネシウム摂取量の違いが運動負荷ラット骨格筋に及ぼす影響2012

    • Author(s)
      柴田龍一、須藤利哉、御牧真代、太田篤胤、酒井健介
    • Organizer
      第67回日本体力医学会
    • Place of Presentation
      長良川国際会議場
    • Related Report
      2011 Final Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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