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Effect of exercise training on strenuous exercise-induced immunosuppression

Research Project

Project/Area Number 22700698
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Applied health science
Research InstitutionWayo Women's University

Principal Investigator

KITAMURA Hiromi  和洋女子大学, 生活科学系, 助教 (00360090)

Research Collaborator MINATO Kumiko  和洋女子大学, 生活科学系, 教授 (70211589)
YANO Hiromi  川崎医療福祉大学, 医療技術学部, 准教授 (20248272)
Project Period (FY) 2010 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywordsスポーツ免疫学 / 自発運動 / オープンウィンドウ / TNF-alpha / LPS / 運動トレーニング / 疲労困憊運動
Research Abstract

Strenuous exercise induces a temporary immunosuppression. The aim of this study was to investigate the effect of exercise trainingon exercise-induced immunosuppression, using the lipopolysaccharide(LPS) injection model. As a result, exercise trainingaffects LPS-induced tumor necrosis factor(TNF)-alpha after acute exercise. This study indicates a possibility that exercise training might not affect the open-window phenomenon.

Report

(3 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • Research Products

    (6 results)

All 2011 2010

All Presentation (6 results)

  • [Presentation] Effect of moderate exercise training on LPS-induced TNF-alpha production in rats2011

    • Author(s)
      Kitamura H, Umetsu Y, Minato K, and Yano H
    • Organizer
      第8回日本運動免疫学研究会
    • Place of Presentation
      海峡メッセ下関(山口県)
    • Year and Date
      2011-09-16
    • Related Report
      2011 Final Research Report
  • [Presentation] Effect of moderate exercise training on LPS-induced TNF-alpha production in rats2011

    • Author(s)
      Kitamura H, Umetsu Y, Minato K, Yano H
    • Organizer
      第8回日本運動免疫学研究会(山口)
    • Place of Presentation
      海峡メッセ下関,山口県
    • Year and Date
      2011-09-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Effect of moderate exercise training on LPS-induced TNF-alpha production in rats2011

    • Author(s)
      Kitamura H, Umetsu Y, Minato K, and Yano H
    • Organizer
      The 10th International Sports and Exercise Immunology Symposium
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2011-07-11
    • Related Report
      2011 Final Research Report
  • [Presentation] Effect of moderate exercise training on LPS-induced TNF-alpha production in rats2011

    • Author(s)
      Kitamura H, Umetsu Y, Minato K, Yano H
    • Organizer
      the 10^<th> International Sports and Exercise Immunology Symposium
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2011-07-11
    • Related Report
      2011 Annual Research Report
  • [Presentation] TNF-alpha production in response to LPS is inhibited by exercise training in rats2010

    • Author(s)
      Kitamura H, Shiroya Y, and Yano H
    • Organizer
      57th Annual Meeting of the American College of Sports Medicine
    • Place of Presentation
      Baltimore, Maryland, USA
    • Year and Date
      2010-06-04
    • Related Report
      2011 Final Research Report
  • [Presentation] TNF-alpha Production In Response To LPS Is Inhibited By Exercise Training In Rats2010

    • Author(s)
      Kitamura H, Shiroya Y, Yano H
    • Organizer
      57th Annual Meeting of the American College of Sports Medicine
    • Place of Presentation
      Baltimore, Maryland, USA
    • Year and Date
      2010-06-04
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2016-04-21  

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