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The search for original protein and biokinetics of antihypertensive peptide derived from Jellyfish Stomolophus nomurai

Research Project

Project/Area Number 22700735
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Eating habits, studies on eating habits
Research InstitutionAomori University of Health and Welfare

Principal Investigator

MORINAGA Yae  青森県立保健大学, 健康科学部, 助教 (40404818)

Research Collaborator MATSUE Hajime  青森県立保健大学, 健康科学部, 教授 (30106843)
IWAI Kunihisa  青森県立保健大学, 健康科学部, 教授 (80404812)
TOMITA Hidehiro  青森県産業技術センター, 下北ブランド研究所, 研究開発部長
UCHISAWA Hidemitsu  青森県工業総合研究センター, 環境技術研究部, 部長
NARAOKA Tetsushi  青森県工業総合研究センター, 企画経営, 担当
Project Period (FY) 2010 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords食素材 / エチゼンクラゲ / ペプチド / 非コラーゲンタンパク質 / コラーゲン / 降圧活性 / タンパク質
Research Abstract

I found the antihypertensive peptide YYAPFE derived from Jellyfish Stomolophus nomurai. The peptide has not a characteristic triple-helical conformation of collagen that is derived from the [Gly-X-Y]n sequence. Therefore, the original protein of the peptide was estimated to be non-collagen protein. Furthermore, I searched long chain peptide derived from non-collagen protein. A new nonadecapeptide was identified as NKPLAGSPAASELYTEAGG. However, the peptide has not ACE inhivitory activity.

Report

(4 results)
  • 2012 Annual Research Report   Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • Research Products

    (6 results)

All 2011 2010

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (4 results)

  • [Journal Article] Chemical Nature of a New Antihypertensive Peptide Derived from Jellyfish2010

    • Author(s)
      Yae Morinaga、 Kunihisa Iwai、 Hidehiro Tomita、 Yoshiaki Takaya、 Tetsushi Naraoka、 Hajime Matsue
    • Journal Title

      Food Science and Technology Research

      Volume: 16 Issue: 4 Pages: 333-340

    • DOI

      10.3136/fstr.16.333

    • NAID

      10027497036

    • ISSN
      1344-6606, 1881-3984
    • Related Report
      2012 Final Research Report
    • Peer Reviewed
  • [Journal Article] Chemical nature of a new antihypertensive peptide derived from jellyfish2010

    • Author(s)
      Yae Morinaga
    • Journal Title

      Food Science and Technology Research

      Volume: 16 Pages: 333-340

    • NAID

      10027497036

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] A New ACE Inhibitory and Antihypertensive Peptide Derived from Jelly fish Stomolophus nomurai2011

    • Author(s)
      Yae Morinaga, Kunihisa Iwai, Hidehiro Tomita, Yoshiaki Takaya, Tetsushi Naraoka, Hajime Matsue
    • Organizer
      ICoFF 2011
    • Place of Presentation
      台北国際会議場
    • Year and Date
      2011-11-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] A New Antihypertensive Peptide Derived from Jellyfish Stomolophus nomurai2011

    • Author(s)
      Yae Morinaga、 Kunihisa Iwai、 Hidehiro Tomita、 Yoshiaki Takaya、 Tetsushi naraoka and Hajime Matsue
    • Organizer
      ICOFF2011
    • Related Report
      2012 Final Research Report
  • [Presentation] エチゼンクラゲ由来降圧活性ペプチドの由来タンパク質の探索2011

    • Author(s)
      森永八江、岩井邦久、 内沢秀光、 富田秀弘、松江一
    • Organizer
      日本農芸化学会2011年度大会
    • Related Report
      2012 Final Research Report
  • [Presentation] エチゼンクラゲ由来降圧活性ペプチドの由来タンパク質の探索2010

    • Author(s)
      森永八江
    • Organizer
      日本農芸化学会
    • Place of Presentation
      京都女子大学(震災により中止)
    • Year and Date
      2010-03-26
    • Related Report
      2010 Annual Research Report

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Published: 2010-08-23   Modified: 2019-07-29  

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