The search for original protein and biokinetics of antihypertensive peptide derived from Jellyfish Stomolophus nomurai
| Project/Area Number |
22700735
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Aomori University of Health and Welfare |
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Principal Investigator |
MORINAGA Yae 青森県立保健大学, 健康科学部, 助教 (40404818)
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| Research Collaborator |
MATSUE Hajime 青森県立保健大学, 健康科学部, 教授 (30106843)
IWAI Kunihisa 青森県立保健大学, 健康科学部, 教授 (80404812)
TOMITA Hidehiro 青森県産業技術センター, 下北ブランド研究所, 研究開発部長
UCHISAWA Hidemitsu 青森県工業総合研究センター, 環境技術研究部, 部長
NARAOKA Tetsushi 青森県工業総合研究センター, 企画経営, 担当
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| Project Period (FY) |
2010 – 2012
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| Project Status |
Completed (Fiscal Year 2012)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 食素材 / エチゼンクラゲ / ペプチド / 非コラーゲンタンパク質 / コラーゲン / 降圧活性 / タンパク質 |
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| Research Abstract |
I found the antihypertensive peptide YYAPFE derived from Jellyfish Stomolophus nomurai. The peptide has not a characteristic triple-helical conformation of collagen that is derived from the [Gly-X-Y]n sequence. Therefore, the original protein of the peptide was estimated to be non-collagen protein. Furthermore, I searched long chain peptide derived from non-collagen protein. A new nonadecapeptide was identified as NKPLAGSPAASELYTEAGG. However, the peptide has not ACE inhivitory activity.
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Report
(4 results)
Research Products
(6 results)
