Optimization of dietary essential fatty aid balance for health promotion and improvement of life quality
Project/Area Number |
22700747
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Eating habits, studies on eating habits
|
Research Institution | Akita University |
Principal Investigator |
|
Project Period (FY) |
2010 – 2012
|
Project Status |
Completed (Fiscal Year 2012)
|
Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | n-3 系脂肪酸 / α-リノレン酸 / ドコサヘキサエン酸 / 間葉系幹細胞 / 脂肪細胞 / 骨芽細胞 / 筋芽細胞 / 脂質栄養教育 / 筋肉細胞 / Myog / Sirt1 / 食品 / リノール酸 / 肥満症 / 骨粗鬆症 / メタボリック / 肥満 |
Research Abstract |
We investigated the effect of n-3 fatty acid on differentiation of mesenchymal stem cells. DHA suppressed adipocyte gene expression and promoted expression of marker genes of both myocyte and osteoblast as well as SIRT1. These results indicate the beneficial effect of n-3 fatty acid for health promotion and improvement of life quality. Using these results, we had the home economic classes about essential fatty acid balance and the diet for junior high students, and the favorable outcomes were obtained.
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Report
(4 results)
Research Products
(34 results)